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Compelling P1 substituent affect on metalloprotease binding profile enables the design of a novel cyclohexyl core scaffold with excellent MMP selectivity and HER-2 sheddase inhibitionBURNS, David M; LI, Yun-Long; COVINGTON, Maryanne B et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 13, pp 3525-3530, issn 0960-894X, 6 p.Article

Design and identification of selective HER-2 sheddase inhibitors via P1' manipulation and unconventional P2' perturbations to induce a molecular metamorphosisWENQING YAO; JINCONG ZHUO; MARANDO, Cindy A et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 1, pp 159-163, issn 0960-894X, 5 p.Article

Discovery of a potent, selective, and orally active human epidermal growth factor receptor-2 sheddase inhibitor for the treatment of cancerWENQING YAO; JINCONG ZHUO; QIYAN LIN et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 4, pp 603-606, issn 0022-2623, 4 p.Article

Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancerFRIDMAN, Jordan S; CAULDER, Eian; GRANDIS, Jennifer R et al.Clinical cancer research. 2007, Vol 13, Num 6, pp 1892-1902, issn 1078-0432, 11 p.Article

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