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Synthetic retinoids : Recent developments concerning structure and clinical utilityKAGECHIKA, Hiroyuki; SHUDO, Koichi.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 19, pp 5875-5883, issn 0022-2623, 9 p.Article

Sorafenib Induces Apoptosis Specifically in Cells Expressing BCR/ABL by inhibiting Its Kinase Activity to Activate the Intrinsic Mitochondrial PathwayKUROSU, Tetsuya; OHKI, Manabu; NAN WU et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 9, pp 3927-3936, issn 0008-5472, 10 p.Article

Activation of the Pl3 Kinase Pathway By Retinoic Acid Mediates Sodium/Iodide Symporter Induction and Iodide Transport in MCF-7 Breast Cancer CellsOHASHI, Emi; KOGAI, Takahiko; KAGECHIKA, Hiroyuki et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 8, pp 3443-3450, issn 0008-5472, 8 p.Article

Novel thyroid hormone receptor antagonists with an N-alkylated diphenylamine skeletonKOMATSU, Takuma; HIRANO, Tomoya; SONGKRAM, Chalermkiat et al.Bioorganic & medicinal chemistry. 2007, Vol 15, Num 9, pp 3115-3126, issn 0968-0896, 12 p.Article

Novel retinoid X receptor (RXR) antagonists having a dicarba-closo-dodecaborane as a hydrophobic moietyOHTA, Kiminori; IIJIMA, Toru; KAWACHI, Emiko et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 23, pp 5913-5918, issn 0960-894X, 6 p.Article

Acidic heterocycles as novel hydrophilic pharmacophore of androgen receptor ligands with a carborane core structureFUJII, Shinya; OHTA, Kiminori; GOTO, Tokuhito et al.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 1, pp 344-350, issn 0968-0896, 7 p.Article

Solvent-dependent conformational and fluorescence change of an N-phenylbenzohydroxamic acid derivative bearing two pyrene moietiesKANAI, Misae; HIRANO, Tomoya; AZUMAYA, Isao et al.Tetrahedron (Oxford. Print). 2012, Vol 68, Num 13, issn 0040-4020, 2738, 2778-2783 [7 p.]Article

Solvent-dependent conformational switching of N-phenylhydroxamic acid and its application in crystal engineeringYAMASAKI, Ryu; TANATANI, Aya; AZUMAYA, Isao et al.Crystal growth & design. 2006, Vol 6, Num 9, pp 2007-2010, issn 1528-7483, 4 p.Article

Determination of endogenous levels of retinoic acid isomers in type II diabetes mellitus patients. Possible correlation with Hba1c valuesYAMAKOSHI, Yuko; FUKASAWA, Hiroshi; YAMAUCHI, Toshimasa et al.Biological & pharmaceutical bulletin. 2002, Vol 25, Num 10, pp 1268-1271, issn 0918-6158, 4 p.Article

Design and synthesis of cyclic urea compounds: a pharmacological study for retinoidal activityKURIHARA, Masaaki; ABU SHARA SHAMSUR ROUF; KANSUI, Hisao et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 16, pp 4131-4134, issn 0960-894X, 4 p.Article

α-glucosidase inhibitors with a 4,5,6,7-tetrachlorophthalimide skeleton pendanted with a cycloalkyl or dicarba-Closo-dodecaborane groupSOU, Sonei; TAKAHASHI, Hiroyasu; YAMASAKI, Ryu et al.Chemical and pharmaceutical bulletin. 2001, Vol 49, Num 6, pp 791-793, issn 0009-2363Article

Cyclic-tri(N-methyl-meta-benzamide)s: substituent effects on the bowl-shaped conformation in the crystal and solution statesKAKUTA, Hiroki; AZUMAYA, Isao; MASU, Hyuma et al.Tetrahedron (Oxford. Print). 2010, Vol 66, Num 42, issn 0040-4020, 8226, 8254-8260 [8 p.]Article

Synthesis and helical properties of aromatic multilayered oligoureasKUDO, Mayumi; KATAGIRI, Kosuke; AZUMAYA, Isao et al.Tetrahedron (Oxford. Print). 2012, Vol 68, Num 23, issn 0040-4020, 4333, 4455-4463 [10 p.]Article

Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release controlSATOH, Taku; HIGUCHI, Yuriko; KAWAKAMI, Shigeru et al.Journal of controlled release. 2009, Vol 136, Num 3, pp 187-195, issn 0168-3659, 9 p.Article

Effects of retinoic acids on the dendritic morphology of cultured hippocampal neuronsYING LIU; KAGECHIKA, Hiroyuki; ISHIKAWA, Junko et al.Journal of neurochemistry. 2008, Vol 106, Num 3, pp 1104-1116, issn 0022-3042, 13 p.Article

Upregulation of nitric oxide production in vascular endothelial cells by all-trans retinoic acid through the phosphoinositide 3-kinase/akt pathwayURUNO, Akira; SUGAWARA, Akira; KANATSUKA, Hiroshi et al.Circulation (New York, N.Y.). 2005, Vol 112, Num 5, pp 727-736, issn 0009-7322, 10 p.Article

Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysisISHIDA, Seiichi; SHIGEMOTO-MOGAMI, Yukari; SHINOZAKI, Youichi et al.Biochemical pharmacology. 2004, Vol 68, Num 11, pp 2177-2186, issn 0006-2952, 10 p.Article

Neuritogenic activity of a genipin derivative in retinal ganglion cells is mediated by retinoic acid receptor β expression through nitric oxide/ S-nitrosylation signalingKORIYAMA, Yoshiki; TAKAGI, Yusuke; CHIBA, Kenzo et al.Journal of neurochemistry. 2011, Vol 119, Num 5-6, pp 1232-1242, issn 0022-3042, 11 p.Article

Identification of Absolute Helical Structures of Aromatic Multilayered Oligo(m-phenylurea)s in SolutionKUDO, Mayumi; HANASHIMA, Takayuki; MURANAKA, Atsuya et al.Journal of organic chemistry. 2009, Vol 74, Num 21, pp 8154-8163, issn 0022-3263, 10 p.Article

The RXR agonists PA024 and HX630 have different abilities to activate LXR/RXR and to induce ABCA1 expression in macrophage cell linesNISHIMAKI-MOGAMI, Tomoko; TAMEHIRO, Norimasa; INOUE, Kazuhide et al.Biochemical pharmacology. 2008, Vol 76, Num 8, pp 1006-1013, issn 0006-2952, 8 p.Article

The transcription factors Nur77 and retinoid X receptors participate in amphetamine-induced locomotor activitiesBOURHIS, Emmanuelle; MAHEUX, Jérome; PAQUET, Brigitte et al.Psychopharmacologia. 2009, Vol 202, Num 4, pp 635-648, issn 0033-3158, 14 p.Article

All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor : Possible involvement of paracrine effects of endogenous vascular endothelial growth factor signalingSAITO, Akiko; SUGAWARA, Akira; IMAIZUMI, Masue et al.Endocrinology (Philadelphia). 2007, Vol 148, Num 3, pp 1412-1423, issn 0013-7227, 12 p.Article

Novel vitamin D receptor ligands bearing a spherical hydrophobic core structure—Comparison of bicyclic hydrocarbon derivatives with boron cluster derivativesWONGMAYURA, Angsuma; FUJII, Shinya; ITO, Shigeru et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 4, pp 1756-1760, issn 0960-894X, 5 p.Article

RXR antagonism induces G₀/G₁ cell cycle arrest and ameliorates obesity by up―regulating the p53 ― p21^Cip1 pathway in adipocytesNAKATSUKA, Atsuko; WADA, Jun; KATAYAMA, Akihiro et al.Journal of pathology (Print). 2012, Vol 226, Num 5, pp 784-795, issn 0022-3417, 12 p.Article