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Sequence specific molecular recognition by a monocationic lexitropsin of the decadeoxyribonucleotide d-[CATGGCCATGl₂: structural and dynamic aspects deduced from high field ¹H-NMR studiesLEE, M; HARTLEY, J. A; PON, R. T et al.Nucleic acids research. 1988, Vol 16, Num 2, pp 665-684, issn 0305-1048Article

N-(2-chloroethyl)-N-nitrosourea tethered to lexitropsin induces minor groove lesions at the p53 cDNA that are more cytotoxic than mutagenicINGA, A; CHEN, F.-X; FRONZA, G et al.Cancer research (Baltimore). 1999, Vol 59, Num 3, pp 689-695, issn 0008-5472Article

Psoralen-lexitropsin hybrids: DNA sequence selectivity of photoinduced cross-linking from MPE footprinting and exonuclease III stop assay, and mode of binding from electric linear dichroismEKAMBARESWARA RAO, K; GOSSELIN, G; MRANI, D et al.Anti-cancer drug design. 1994, Vol 9, Num 3, pp 221-237, issn 0266-9536Article

N-(2-chloroethyl)-N-nitrosoureas covalently bound to nonionic and monocationic lexitropsin dipeptides. Synthesis, DNA affinity binding characteristics, and reactions with ³²P-end-labeled DNACHURCH, K. M; WURDEMAN, R. L; YI ZHANG et al.Biochemistry (Easton). 1990, Vol 29, Num 29, pp 6827-6838, issn 0006-2960, 12 p.Article

Contribution à la modélisation théorique de la spécificité Ligands-acides nucléiques = Contribution to the theorotical modelization of the Ligands-nucleic acids specificityRandrianarivelo Andriantahinjanahary, Mamizo Tovondrahona; Pullman, Bernard.1991, 165 p.Thesis

Thermodynamic data from drug-DNA footprinting experimentsDABROWIAK, J. C; GOODISMAN, J; KISSINGER, K et al.Biochemistry (Easton). 1990, Vol 29, Num 26, pp 6139-6145, issn 0006-2960, 7 p.Article

Molecular recognition between oligopeptides and nuclei acids: monocationic imidazole lexitropsins that display enhanced GC sequence dependent DNA bindingKISSINGER, K; KROWICKI, K; DABROWIAK, J. C et al.Biochemistry (Easton). 1987, Vol 26, Num 18, pp 5590-5595, issn 0006-2960Article

Advances in DNA-ligands with groove binding, intercalating and/or alkylating activity : Chemistry, DNA-binding and biologyPINDUR, Ulf; JANSEN, Michaela; LEMSTER, Thomas et al.Current medicinal chemistry. 2005, Vol 12, Num 24, pp 2805-2847, issn 0929-8673, 43 p.Article

Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugatesROMAGNOLI, Romeo; GIOVANNI BARALDI, Pier; ANTONIETTA IACONINOTO, Maria et al.European journal of medicinal chemistry. 2005, Vol 40, Num 11, pp 1123-1128, issn 0223-5234, 6 p.Article

DNA minor groove alkylating agentsDENNY, William A.Current medicinal chemistry. 2001, Vol 8, Num 5, pp 533-544, issn 0929-8673Article

Recent developments in sequence selective minor groove DNA effectorsREDDY, B. S. P; SHARMA, S. K; LOWN, J. W et al.Current medicinal chemistry. 2001, Vol 8, Num 5, pp 475-508, issn 0929-8673Article

Cytotoxic and clastogenic effects of a DNA minor groove binding methyl sulfonate ester in mismatch repair deficient leukemic cellsTENTORI, L; VERNOLE, P; BONMASSAR, E et al.Leukemia. 2000, Vol 14, Num 8, pp 1451-1459, issn 0887-6924Article

Enediyne-lexitropsin DNA-targeted anticancer agents. Physicochemical and cytotoxic properties in human neoplastic cells in vitro, and intracellular distributionXIE, Y; MILLER, G. G; CUBITT, S. A et al.Anti-cancer drug design. 1997, Vol 12, Num 3, pp 169-179, issn 0266-9536Article

Influence of the methyl substituents of a thiazole-containing lexitropsin on the mode of binding to DNAPLOUVIER, B; HOUSSIN, R; HELBECQUE, N et al.Anti-cancer drug design. 1995, Vol 10, Num 2, pp 155-166, issn 0266-9536Article

Synthesis and DNA cleaving properties of hybrid molecules containing propargylic sulfones and minor groove binding lexitropsinsXIE, G; MORGAN, A. R; LOWN, J. W et al.Bioorganic & medicinal chemistry letters (Print). 1993, Vol 3, Num 8, pp 1565-1570, issn 0960-894XArticle

DNA sequence-selective binding of head-to-tail linked bis-lexitropsins: relation of phasing to cytotoxic potencyDEQI GUO; RAJAN GUPTA; LOWN, J. W et al.Anti-cancer drug design. 1993, Vol 8, Num 5, pp 369-397, issn 0266-9536Article

Microgonotropens and their interactions with DNA. III: Structural analysis of the 1:1 complex of d(CGCAAATTTGCG)₂ and dien-microgonotropen-c by 2D NMR spectroscopy and restrained molecular modelingBLASKO, A; BROWNE, K. A; GONG-XIN HE et al.Journal of the American Chemical Society. 1993, Vol 115, Num 16, pp 7080-7092, issn 0002-7863Article

Antimicrobial Lexitropsins Containing Amide, Amidine, and Alkene Linking GroupsANTHONY, Nahoum G; BREEN, David; MACKAY, Simon P et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 24, pp 6116-6125, issn 0022-2623, 10 p.Article

DNA minor groove binders : An overview on molecular modeling and QSAR approachesLAURIA, Antonino; MONTALBANO, Alessandra; BARRAJA, Paola et al.Current medicinal chemistry. 2007, Vol 14, Num 20, pp 2136-2160, issn 0929-8673, 25 p.Article

DNA binding of a short lexitropsinANTHONY, Nahoum G; FOX, Keith R; JOHNSTON, Blair F et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 5, pp 1353-1356, issn 0960-894X, 4 p.Article

Sequence recognition of DNA by lexitropsinsGOODSELL, David S.Current medicinal chemistry. 2001, Vol 8, Num 5, pp 509-516, issn 0929-8673Article

Design, synthesis, DNA sequence preferential alkylation and biological evaluation of N-mustard derivatives of distamycin and netropsin analoguesXIE, G; GUPTA, R; LOWN, J. W et al.Anti-cancer drug design. 1995, Vol 10, Num 5, pp 389-409, issn 0266-9536Article

Design and development of sequence selective lexitropsin DNA minor groove bindersLOWN, J. W.Drug development research. 1995, Vol 34, Num 2, pp 145-183, issn 0272-4391Article

Design of DNA-cleaving molecules which incorporate a simplified metal-complexing moiety of bleomycin and lexitropsin carriersHUANG, L; MORGAN, A. R; LOWN, J. W et al.Bioorganic & medicinal chemistry letters (Print). 1993, Vol 3, Num 8, pp 1751-1756, issn 0960-894XArticle