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Results 1 to 25 of 52

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Pharmacodynamic considerations in bioequivalence assessment: comparison of novel and existing metricsKARALIS, Vangelis; MACHERAS, Panos.European journal of pharmaceutical sciences. 2003, Vol 19, Num 1, pp 45-56, issn 0928-0987, 12 p.Article

Monte Carlo simulations for the study of drug release from matrices with high and low diffusivity areasKOSMIDIS, Kosmas; MACHERAS, Panos.International journal of pharmaceutics. 2007, Vol 343, Num 1-2, pp 166-172, issn 0378-5173, 7 p.Article

A century of dissolution research : From Noyes and Whitney to the Biopharmaceutics Classification SystemDOKOUMETZIDIS, Aristides; MACHERAS, Panos.International journal of pharmaceutics. 2006, Vol 321, Num 1-2, pp 1-11, issn 0378-5173, 11 p.Article

Drug disposition viewed in terms of the fractal volume of distributionKARALIS, Vangelis; MACHERAS, Panos.Pharmaceutical research. 2002, Vol 19, Num 5, pp 696-703, issn 0724-8741Article

An Insight into the Properties of a Two-Stage Design in Bioequivalence StudiesKARALIS, Vangelis; MACHERAS, Panos.Pharmaceutical research. 2013, Vol 30, Num 7, pp 1824-1835, issn 0724-8741, 12 p.Article

Monte Carlo simulations of drug release from matrices with periodic layers of high and low diffusivityKOSMIDIS, Kosmas; MACHERAS, Panos.International journal of pharmaceutics. 2008, Vol 354, Num 1-2, pp 111-116, issn 0378-5173, 6 p.Article

Novel milk-based oral formulations: Proof of conceptCHARKOFTAKI, Georgia; KYTARIOLOS, John; MACHERAS, Panos et al.International journal of pharmaceutics (Print). 2010, Vol 390, Num 2, pp 150-159, issn 0378-5173, 10 p.Article

Geometric mean ratio-dependent scaled bioequivalence limits with leveling-off propertiesKARALIS, Vangelis; MACHERAS, Panos; SYMILLIDES, Mira et al.European journal of pharmaceutical sciences. 2005, Vol 26, Num 1, pp 54-61, issn 0928-0987, 8 p.Article

Quantitative structure-pharmacokinetic relationships for disposition parameters of cephalosporinsKARALIS, Vangelis; TSANTILI-KAKOULIDOU, Anna; MACHERAS, Panos et al.European journal of pharmaceutical sciences. 2003, Vol 20, Num 1, pp 115-123, issn 0928-0987, 9 p.Article

The mean dissolution time depends on the dose/solubility ratioRINAKI, Eleni; DOKOUMETZIDIS, Aristides; MACHERAS, Panos et al.Pharmaceutical research. 2003, Vol 20, Num 3, pp 406-408, issn 0724-8741, 3 p.Article

Multivariate statistics of disposition pharmacokinetic parameters for structurally unrelated drugs used in therapeuticsKARALIS, Vangelis; TSANTILI-KAKOULIDOU, Anna; MACHERAS, Panos et al.Pharmaceutical research. 2002, Vol 19, Num 12, pp 1827-1834, issn 0724-8741, 8 p.Article

Analysis of dissolution data using modified versions of noyes-whitney equation and the weibull functionDOKOUMETZIDIS, Aristides; PAPADOPOULOU, Vasiliki; MACHERAS, Panos et al.Pharmaceutical research. 2006, Vol 23, Num 2, pp 256-261, issn 0724-8741, 6 p.Article

Quantitative biopharmaceutics classification system: The central role of dose/solubility ratioRINAKI, Eleni; VALSAMI, Georgia; MACHERAS, Panos et al.Pharmaceutical research. 2003, Vol 20, Num 12, pp 1917-1925, issn 0724-8741, 9 p.Article

A stochastic model describes the heterogeneous pharmacokinetics of cyclosporinCLARET, Laurent; ILIADIS, Athanassios; MACHERAS, Panos et al.Journal of pharmacokinetics and biopharmaceutics. 2001, Vol 28, Num 5, pp 445-463, issn 0090-466XArticle

Non-linear regression analysis with errors in both variables : Estimation of co-operative binding parametersVALSAMI, Georgia; ILIADIS, Athanassios; MACHERAS, Panos et al.Biopharmaceutics & drug disposition. 2000, Vol 21, Num 1, pp 7-14, issn 0142-2782Article

Bioequivalence of Highly Variable Drugs: A Comparison of the Newly Proposed Regulatory Approaches by FDA and EMAKARALIS, Vangelis; SYMILLIDES, Mira; MACHERAS, Panos et al.Pharmaceutical research. 2012, Vol 29, Num 4, pp 1066-1077, issn 0724-8741, 12 p.Article

Biopharmaceutics classification systems for new molecular entities (BCS-NMEs) and marketed drugs (BCS-MD) : Theoretical basis and practical examplesPAPADOPOULOU, Vasiliki; VALSAMI, Georgia; DOKOUMETZIDIS, Aristides et al.International journal of pharmaceutics. 2008, Vol 361, Num 1-2, pp 70-77, issn 0378-5173, 8 p.Article

Novel scaled bioequivalence limits with leveling-off propertiesKYTARIOLOS, John; KARALIS, Vangelis; MACHERAS, Panos et al.Pharmaceutical research. 2006, Vol 23, Num 11, pp 2657-2664, issn 0724-8741, 8 p.Article

Modeling and monte carlo simulations in oral drug absorptionDOKOUMETZIDIS, Aristides; KOSMIDIS, Kosmas; ARGYRAKIS, Panos et al.Basic & clinical pharmacology & toxicology (Print). 2005, Vol 96, Num 3, pp 200-205, issn 1742-7835, 6 p.Article

A reappraisal of drug release laws using Monte Carlo simulations: The prevalence of the Weibull functionKOSMIDIS, Kosmas; ARGYRAKIS, Panos; MACHERAS, Panos et al.Pharmaceutical research. 2003, Vol 20, Num 7, pp 988-995, issn 0724-8741, 8 p.Article

Fractal volume of drug distribution : It scales proportionally to body massKARALIS, Vangelis; CLARET, Laurent; ILIADIS, Athanassios et al.Pharmaceutical research. 2001, Vol 18, Num 7, pp 1056-1060, issn 0724-8741Article

Elucidating the Role of Dose in the Biopharmaceutics Classification of Drugs: The Concepts of Critical Dose, Effective In Vivo Solubility, and Dose-Dependent BCSCHARKOFTAKI, Georgia; DOKOUMETZIDIS, Aristides; VALSAMI, Georgia et al.Pharmaceutical research. 2012, Vol 29, Num 11, pp 3188-3198, issn 0724-8741, 11 p.Article

On the leveling-off properties of the new bioequivalence limits for highly variable drugs of the EMA guidelineKARALIS, Vangelis; SYMILLIDES, Mira; MACHERAS, Panos et al.European journal of pharmaceutical sciences. 2011, Vol 44, Num 4, pp 497-505, issn 0928-0987, 9 p.Article

Power law IVIVC: An application of fractional kinetics for drug release and absorptionKYTARIOLOS, John; DOKOUMETZIDIS, Aristides; MACHERAS, Panos et al.European journal of pharmaceutical sciences. 2010, Vol 41, Num 2, pp 299-304, issn 0928-0987, 6 p.Article

Comparison of the reference scaled bioequivalence semi-replicate method with other approaches: Focus on human exposure to drugsKARALIS, Vangelis; SYMILLIDES, Mira; MACHERAS, Panos et al.European journal of pharmaceutical sciences. 2009, Vol 38, Num 1, pp 55-63, issn 0928-0987, 9 p.Article

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