Design, synthesis and biological evaluation of 2H-benzo[b][1,4] oxazine derivatives as hypoxia targeted compounds for cancer therapeuticsDAS, Bhaskar C; MADHUKUMAR, Ankanahlli V; ANGUIANO, Jaime et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 15, pp 4204-4206, issn 0960-894X, 3 p.Article

Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 geneKRAUSOVA, Lucie; STEJSKALOVA, Lucie; HONGWEI WANG et al.Biochemical pharmacology. 2011, Vol 82, Num 11, pp 1771-1780, issn 0006-2952, 10 p.Article

PXR antagonists and implication in drug metabolismMANI, Sridhar; WEI DOU; REDINBO, Matthew R et al.Drug metabolism reviews (Softcover ed.). 2013, Vol 45, Num 1, pp 60-72, issn 0360-2532, 13 p.Article

Elucidating the 'Jekyll and Hyde' Nature of PXR: The Case for Discovering Antagonists or Allosteric AntagonistsBISWAS, Arunima; MANI, Sridhar; REDINBO, Matthew R et al.Pharmaceutical research. 2009, Vol 26, Num 8, pp 1807-1815, issn 0724-8741, 9 p.Article

Phase I and Pharmacokinetic Study of Imatinib Mesylate in Patients With Advanced Malignancies and Varying Degrees of Renal Dysfunction : A Study by the National Cancer Institute Organ Dysfunction Working GroupGIBBONS, Joseph; EGORIN, Merrill J; PAVLICK, Anna et al.Journal of clinical oncology. 2008, Vol 26, Num 4, pp 570-576, issn 0732-183X, 7 p.Article

A safety study of a mixed-backbone oligonucleotide (GEM231) targeting the type I regulatory subunit a of protein kinase A using a continuous infusion schedule in patients with refractory solid tumorsGOEL, Sanjay; DESAI, Kavita; BULGARU, Anca et al.Clinical cancer research. 2003, Vol 9, Num 11, pp 4069-4076, issn 1078-0432, 8 p.Article

Induction of CYP3A4 by Vinblastine: Role of the Nuclear Receptor NR112SMITH, Nicola F; MANI, Sridhar; SCHUETZ, Erin G et al.The Annals of pharmacotherapy. 2010, Vol 44, Num 11, pp 1709-1717, issn 1060-0280, 9 p.Article

Activated pregnenolone X-receptor is a target for ketoconazole and its analogsHONGWEI WANG; HAIYAN HUANG; HAO LI et al.Clinical cancer research. 2007, Vol 13, Num 8, pp 2488-2495, issn 1078-0432, 8 p.Article

Dose-escalating and pharmacologic study of oxaliplatin in adult cancer patients with impaired hepatic function : A national cancer institute organ dysfunction working group studySYNOLD, Timothy W; TAKIMOTO, Chris H; LENZ, Heinz Josef et al.Clinical cancer research. 2007, Vol 13, Num 12, pp 3660-3666, issn 1078-0432, 7 p.Article

Clinical and pharmacokinetic study evaluating the effect of food on the disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in patients with solid tumorsZAMBONI, William C; GOEL, Sanjay; IQBAL, Tahir et al.Cancer chemotherapy and pharmacology. 2006, Vol 57, Num 5, pp 631-639, issn 0344-5704, 9 p.Article

Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumorsMANI, Sridhar; MCDAID, Hayley; HORWITZ, Susan Band et al.Clinical cancer research. 2004, Vol 10, Num 4, pp 1289-1298, issn 1078-0432, 10 p.Article

Phase I clinical and pharmacogenetic study of weekly TAS-103 in patients with advanced cancerEWESUEDO, Reginald B; LYER, Lalitha; DAS, Soma et al.Journal of clinical oncology. 2001, Vol 19, Num 7, pp 2084-2090, issn 0732-183XArticle

Pharmacokinetics and Safety of Bortezomib in Patients with Advanced Malignancies and Varying Degrees of Liver Dysfunction: Phase I NCI Organ Dysfunction Working Group Study NCI-6432LORUSSO, Patricia M; VENKATAKRISHNAN, Karthik; TAKIMOTO, Chris H et al.Clinical cancer research (Print). 2012, Vol 18, Num 10, pp 2954-2963, issn 1078-0432, 10 p.Article

Phase I dose escalation study of KOS-1584, a novel epothilone, in patients with advanced solid tumorsLAM, Elaine T; GOEL, Sanjay; VILLALONA-CALERO, Miguel A et al.Cancer chemotherapy and pharmacology. 2012, Vol 69, Num 2, pp 523-531, issn 0344-5704, 9 p.Article

Safety, Pharmacokinetics, and Activity of EZN-2208, a Novel Conjugate of Polyethylene Glycol and SN38, in Patients With Advanced MalignanciesKURZROCK, Razelle; GOEL, Sanjay; GHALIB, Mohammed H et al.Cancer. 2012, Vol 118, Num 24, pp 6144-6151, issn 0008-543X, 8 p.Article

Dose-escalating and pharmacological study of bortezomib in adult cancer patients with impaired renal function: a National Cancer Institute Organ Dysfunction Working Group StudyLEAL, Ticiana B; REMICK, Scot C; MIER, James et al.Cancer chemotherapy and pharmacology. 2011, Vol 68, Num 6, pp 1439-1447, issn 0344-5704, 9 p.Article

Oxaliplatin pharmacokinetics and pharmacodynamics in adult cancer patients with impaired renal functionTAKIMOTO, Chris H; GRAHAM, Martin A; SYNOLD, Timothy W et al.Clinical cancer research. 2007, Vol 13, Num 16, pp 4832-4839, issn 1078-0432, 8 p.Article

A phase II study of rebeccamycin analog NSC 655649 in patients with metastatic colorectal cancerGOEL, Sanjay; WADLER, Scott; HOFFMAN, Anthony et al.Investigational new drugs. 2003, Vol 21, Num 1, pp 103-107, issn 0167-6997, 5 p.Article

Phase I clinical and pharmacokinetic study of protein kinase C-α antisense oligonucleotide ISIS 3521 administered in combination with 5-fluorouracil and leucovorin in patients with advanced cancerMANI, Sridhar; RUDIN, Charles M; KUNKEL, Katie et al.Clinical cancer research. 2002, Vol 8, Num 4, pp 1042-1048, issn 1078-0432Article

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial EnzymeWALLACE, Bret D; HONGWEI WANG; REDINBO, Matthew R et al.Science (Washington, D.C.). 2010, Vol 330, Num 6005, pp 831-835, issn 0036-8075, 5 p.Article

Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR)DAS, Bhaskar C; MADHUKUMAR, Ankanahlli V; ANGUIANO, Jaime et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 14, pp 3974-3977, issn 0960-894X, 4 p.Article

Phase i study of inhaled doxorubicin for patients with metastatic tumors to the lungsOTTERSON, Gregory A; VILLALONA-CALERO, Miguel A; KRAUT, Michael et al.Clinical cancer research. 2007, Vol 13, Num 4, pp 1246-1252, issn 1078-0432, 7 p.Article

Autoantibody cancer biomarker : Extracellular protein kinase aNESTEROVA, Maria V; JOHNSON, Natalie; CHEADLE, Christopher et al.Cancer research (Baltimore). 2006, Vol 66, Num 18, pp 8971-8974, issn 0008-5472, 4 p.Article

Phase I and pharmacokinetic study of the novel redox-active agent, motexafin gadolinium, with concurrent radiation therapy in patients with locally advanced pancreatic or biliary cancersRAMANATHAN, Ramesh K; FAKIH, Marwan; PARISE, Robert A et al.Cancer chemotherapy and pharmacology. 2006, Vol 57, Num 4, pp 465-474, issn 0344-5704, 10 p.Article

Activation of the steroid and xenobiotic receptor (Human pregnane X receptor) by nontaxane microtubule -stabilizing agentsMANI, Sridhar; HAIYAN HUANG; SUNDARABABU, Sumathy et al.Clinical cancer research. 2005, Vol 11, Num 17, pp 6359-6369, issn 1078-0432, 11 p.Article