Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replicationBALZARINI, Jan; MCGUIGAN, Christopher.Journal of antimicrobial chemotherapy (Print). 2002, Vol 50, Num 1, pp 5-9, issn 0305-7453Article

Aryl furano pyrimidines : The most potent and selective anti-VZV agents reported to dateMCGUIGAN, Christopher; BALZARINI, Jan.Antiviral research. 2006, Vol 71, Num 2-3, pp 149-153, issn 0166-3542, 5 p.Article

Clostridium novyi type A infection: A sporadic fatal caseMCGUIGAN, Christopher; ROWORTH, Michael.Scandinavian journal of infectious diseases. 2002, Vol 34, Num 3, pp 209-211, issn 0036-5548Article

Design, synthesis, and anti-HIV activity of 2',3' -didehydro -2',3'-dideoxyuridine (d4U), 2',3'-dideoxyuridine (ddU) phosphoramidate 'ProTide' derivativesMEHELLOU, Youcef; MCGUIGAN, Christopher; BRANCALE, Andrea et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 13, pp 3666-3669, issn 0960-894X, 4 p.Article

A synovial cyst in the cervical spine causing acute spinal cord compressionMCGUIGAN, Christopher; STEVENS, John; GABRIEL, Carolyn M et al.Neurology. 2005, Vol 65, Num 8, issn 0028-3878, p. 1293Article

The phosphoramidate ProTide approach greatly enhances the activity of β-2'-C-methylguanosine against hepatitis C virusMCGUIGAN, Christopher; PERRONE, Plinio; MADELA, Karolina et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 15, pp 4316-4320, issn 0960-894X, 5 p.Article

Synthesis and evaluation of novel amidate prodrugs of PMEA and PMPABALLATORE, Carlo; MCGUIGAN, Christopher; DE CLERCQ, Erik et al.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 8, pp 1053-1056, issn 0960-894XArticle

Bicyclic nucleoside inhibitors of varicella-zoster virus modified on the sugar moiety: 3' and 5' derivativesLUONI, Giovanna M; MCGUIGAN, Christopher; ANDREI, Graciela et al.Antiviral chemistry & chemotherapy. 2004, Vol 15, Num 6, pp 333-341, issn 0956-3202, 9 p.Article

A QSAR study investigating the effect of L-alanine ester variation on the anti-HIV activity of some phosphoramidate derivatives of d4TKNAGGS, Michael H; MCGUIGAN, Christopher; HARRIS, Sarah A et al.Bioorganic & medicinal chemistry letters (Print). 2000, Vol 10, Num 18, pp 2075-2078, issn 0960-894XArticle

The Application of Phosphoramidate Protide Technology to Acyclovir Confers Anti-HIV InhibitionDERUDAS, Marco; CARTA, Davide; BRANCALE, Andrea et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 17, pp 5520-5530, issn 0022-2623, 11 p.Article

Activation of p16 Gene Silenced by DNA Methylation in Cancer Cells by Phosphoramidate Derivatives of 2'-DeoxyzebularineYOO, Christine B; VALENTE, Rocco; CONGIATU, Costantino et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 23, pp 7593-7601, issn 0022-2623, 9 p.Article

First example of phosphoramidate approach applied to a 4'-substituted purine nucleoside (4'-azidoadenosine) : Conversion of an inactive nucleoside to a submicromolar compound versus hepatitis C virusPERRONE, Plinio; DAVERIO, Felice; MCGUIGAN, Christopher et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 22, pp 5463-5470, issn 0022-2623, 8 p.Article

Synthesis and Antiviral Activity of the Carbocyclic Analogue of the Highly Potent and Selective Anti-VZV Bicyclo Furano PyrimidinesMIGLIORE, Marco D; ZONTA, Nicola; MCGUIGAN, Christopher et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 26, pp 6485-6492, issn 0022-2623, 8 p.Article

Population frequency of HLA haplotypes contributes to the prevalence difference of multiple sclerosis in IrelandMCGUIGAN, Christopher; DUNNE, Ciaran; CROWLEY, John et al.Journal of neurology. 2005, Vol 252, Num 10, pp 1245-1248, issn 0340-5354, 4 p.Article

Novel bicyclic furanopyrimidines with dual anti-VZV and -HCMV activityMCGUIGAN, Christopher; BRANCALE, Andrea; ANDREI, Graciela et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 24, pp 4511-4513, issn 0960-894X, 3 p.Article

Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chainMCGUIGAN, Christopher; BARUCKI, Hubert; BLEWETT, Sally et al.Journal of medicinal chemistry (Print). 2000, Vol 43, Num 26, pp 4993-4997, issn 0022-2623Article

Symptom overlap in anxiety and multiple sclerosisDONNCHADHA, Seán O; BURKE, Teresa; MCGUIGAN, Christopher et al.Multiple sclerosis. 2013, Vol 19, Num 10, pp 1349-1354, issn 1352-4585, 6 p.Article

Dual pro-drugs of 2'-C-methyl guanosine monophosphate as potent and selective inhibitors of hepatitis C virusMCGUIGAN, Christopher; MADELA, Karolina; KOLYKHALOV, Alexander et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 19, pp 6007-6012, issn 0960-894X, 6 p.Article

Synthesis and antiviral evaluation of α-L-2'-deoxythreofuranosyl nucleosidesTOTI, Kiran S; DERUDAS, Marco; MCGUIGAN, Christopher et al.European journal of medicinal chemistry. 2011, Vol 46, Num 9, pp 3704-3713, issn 0223-5234, 10 p.Article

The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4'-azidocytidine (R1479)MCGUIGAN, Christopher; ROSE KELLEHER, Mary; KLUMPP, Klaus et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 15, pp 4250-4254, issn 0960-894X, 5 p.Article

2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743MCGUIGAN, Christopher; DERUDAS, Marco; QUINTILIANI, Maurizio et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 22, pp 6264-6267, issn 0960-894X, 4 p.Article

Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virusMCGUIGAN, Christopher; PATHIRANA, Ranjith N; VERBEKEN, Erik et al.Journal of antimicrobial chemotherapy (Print). 2007, Vol 60, Num 6, pp 1316-1330, issn 0305-7453, 15 p.Article

Application of phosphoramidate pronucleotide technology to abacavir leads to a significant enhancement of antiviral potencyMCGUIGAN, Christopher; HARRIS, Sarah A; DE CLERCQ, Erik et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 10, pp 3504-3515, issn 0022-2623, 12 p.Article

Alkyloxyphenyl furano pyrimidines as potent and selective anti-VZV agents with enhanced water solubilityMCGUIGAN, Christopher; BLEWETT, Sally; SICCARDI, Dario et al.Antiviral chemistry & chemotherapy. 2002, Vol 13, Num 2, pp 91-99, issn 0956-3202Article

Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): The effect of terminal unsaturation in the side chainSRINIVASAN, Sheila; MCGUIGAN, Christopher; ANDREI, Graciela et al.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 3, pp 391-393, issn 0960-894XArticle