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au.\*:("MIHARA, Kayoko")

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Restoration of middle cerebral artery thrombosis by novel glycoprotein IIb/IIIa antagonist FK419 in guinea pigMORIGUCHI, Akira; MIHARA, Kayoko; AOKI, Toshiaki et al.European journal of pharmacology. 2004, Vol 498, Num 1-3, pp 179-188, issn 0014-2999, 10 p.Article

4-phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitorsISHIDA, Junya; HATTORI, Kouji; YAMAMOTO, Hirofumi et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 19, pp 4221-4225, issn 0960-894X, 5 p.Article

FK419, a novel nonpeptide GPIIb/IIIa antagonist, restores microvascular patency and improves outcome in the guinea-pig middle cerebral artery thrombotic occlusion model : comparison with tirofibanMORIGUCHI, Akira; MAEDA, Masashi; MIHARA, Kayoko et al.Journal of cerebral blood flow and metabolism. 2005, Vol 25, Num 1, pp 75-86, issn 0271-678X, 12 p.Article

Rational design of conformationally restricted quinazolinone inhibitors of poly(ADP-ribose)polymeraseHATTORI, Kouji; KIDO, Yoshiyuki; YAMAMOTO, Hirofumi et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 20, pp 5577-5581, issn 0960-894X, 5 p.Article

Design, synthesis, and structure-activity relationships of potent GPIIb/IIIa antagonists : discovery of FK419YAMANAKA, Toshio; OHKUBO, Mitsuru; KURODA, Satoru et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 13, pp 4343-4352, issn 0968-0896, 10 p.Article

Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymeraseHATTORI, Kouji; KIDO, Yoshiyuki; YAMAZAKI, Syunji et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 17, pp 4151-4154, issn 0022-2623, 4 p.Article

Inhibition of arterial thrombosis by a protease-activated receptor 1 antagonist, FR171113, in the guinea pigKATO, Yasuko; KITA, Yasuhiro; HIRASAWA-TANIYAMA, Yoshimi et al.European journal of pharmacology. 2003, Vol 473, Num 2-3, pp 163-169, issn 0014-2999, 7 p.Article

Discovery of potent and selective PARP-1 and PARP-2 inhibitors : SBDD analysis via a combination of X-ray structural study and homology modelingISHIDA, Junya; YAMAMOTO, Hirofumi; MIHARA, Kayoko et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 5, pp 1378-1390, issn 0968-0896, 13 p.Article

Characterization of the anti-platelet actions of FK419, a novel non-peptide antagonist of platelet GPIIb/IIIaMIHARA, Kayoko; AOKI, Toshiaki; MUTOH, Seitaro et al.Drug development research. 2004, Vol 61, Num 4, pp 233-241, issn 0272-4391, 9 p.Article

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