IL-6/IL-6 receptor system and its role in physiological and pathological conditionsMIHARA, Masahiko; HASHIZUME, Misato; YOSHIDA, Hiroto et al.Clinical science (1979). 2012, Vol 122, Num 3-4, pp 143-159, issn 0143-5221, 17 p.Article

Instability of Foxp3 Expression Limits the Ability of Induced Regulatory T Cells to Mitigate Graft versus Host DiseaseBERES, Amy; KOMOROWSKI, Richard; MIHARA, Masahiko et al.Clinical cancer research (Print). 2011, Vol 17, Num 12, pp 3969-3983, issn 1078-0432, 15 p.Article

Overproduced interleukin 6 decreases blood lipid levels via upregulation of very-low-density lipoprotein receptorHASHIZUME, Misato; YOSHIDA, Hiroto; KOIKE, Nobuo et al.Annals of the rheumatic diseases. 2010, Vol 69, Num 4, pp 741-746, issn 0003-4967, 6 p.Article

Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine familyMIHARA, Masahiko; KASUTANI, Keiko; OKAZAKI, Makoto et al.International immunopharmacology. 2005, Vol 5, Num 12, pp 1731-1740, issn 1567-5769, 10 p.Article

Polyglutamation of a novel antifolate, MX-68, is not necessary for its anti-arthritic effectURAKAWA, Kazumi; MIHARA, Masahiko; TAKAGI, Nobuhiro et al.European journal of pharmacology. 2002, Vol 435, Num 2-3, pp 237-244, issn 0014-2999Article

Humanized antibody to human interleukin-6 receptor inhibits the development of collagen arthritis in cynomolgus monkeysMIHARA, Masahiko; KOTOH, Masao; TAKEDA, And Yasuhisa et al.Clinical immunology (Orlando, Fla. Print). 2001, Vol 98, Num 3, pp 319-326, issn 1521-6616Article

Combination treatment with eldecalcitol (ED-71) and raloxifene improves bone mechanical strength by suppressing bone turnover and increasing bone mineral density in ovariectomized ratsTAKEDA, Satoshi; SAKAI, Sadaoki; SHIRAISHI, Ayako et al.Bone (New York, NY). 2013, Vol 53, Num 1, pp 167-173, issn 8756-3282, 7 p.Article

Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3 (STAT3) promotes choroidal neovascularizationIZUMI-NAGAI, Kanako; NAGAI, Norihiro; OKANO, Hideyuki et al.The American journal of pathology. 2007, Vol 170, Num 6, pp 2149-2158, issn 0002-9440, 10 p.Article

Effects of anti-CD154 treatment on B cells in murine systemic lupus erythematosusXIAOBO WANG; WEIQING HUANG; SCHIFFER, Lena E et al.Arthritis and rheumatism. 2003, Vol 48, Num 2, pp 495-506, issn 0004-3591, 12 p.Article

Crucial Role of the Interleukin-6/Interleukin-17 Cytokine Axis in the Induction of Arthritis by Glucose-6-Phosphate IsomeraseIWANAMI, Keiichi; MATSUMOTO, Isao; KISHIMOTO, Tadamitsu et al.Arthritis and rheumatism. 2008, Vol 58, Num 3, pp 754-763, issn 0004-3591, 10 p.Article

Interleukin-6 Blockade Suppresses Autoimmune Arthritis in Mice by the Inhibition of Inflammatory Th17 ResponsesFUJIMOTO, Minoru; SERADA, Satoshi; KISHIMOTO, Tadamitsu et al.Arthritis and rheumatism. 2008, Vol 58, Num 12, pp 3710-3719, issn 0004-3591, 10 p.Article

Murine Tumor Necrosis Factor α―Induced Adipose-Related Protein (Tumor Necrosis Factor α―Induced Protein 9) Deficiency Leads to Arthritis via Interleukin-6 Overproduction With Enhanced NF-_KB, STAT-3 Signaling, and Dysregulated Apoptosis of MacrophagesINOUE, Asuka; MATSUMOTO, Isao; TANAKA, Yoko et al.Arthritis and rheumatism. 2012, Vol 64, Num 12, pp 3877-3885, issn 0004-3591, 9 p.Article

Anti-IL-6 receptor antibody increases blood IL-6 level via the blockade of IL-6 clearance, but not via the induction of IL-6 productionUCHIYAMA, Yasushi; YOSHIDA, Hiroto; KOIKE, Nobuo et al.International immunopharmacology. 2008, Vol 8, Num 11, pp 1595-1601, issn 1567-5769, 7 p.Article

Anti-interleukin 6 receptor antibody inhibits murine AA-amyloidosisMIHARA, Masahiko; SHIINA, Masashi; NISHIMOTO, Norihiro et al.Journal of rheumatology. 2004, Vol 31, Num 6, pp 1132-1138, issn 0315-162X, 7 p.Article