PHENYLKETONURIA AND ITS VARIANTS.KAUFMAN S; MILSTIEN S.1977; ANN. CLIN. LAB. SCI.; U.S.A.; DA. 1977; VOL. 7; NO 2; PP. 178-185; BIBL. 31 REF.Article

STUDIES ON THE PHENYLALANINE HYDROXYLASE SYSTEM IN LIVER SLICES.MILSTIEN S; KAUFMAN S.1975; J. BIOL. CHEM.; U.S.A.; DA. 1975; VOL. 250; NO 12; PP. 4777-4781; BIBL. 22 REF.Article

STUDIES ON THE PHENYLALANINE HYDROXYLASE SYSTEM IN VIVO. AN IN VIVO ASSAY BASED ON THE LIBERATION OF DEUTERIUM OR TRITIUM INTO THE BODY WATER FROM RING-LABELED L-PHENYLALANINE.MILSTIEN S; KAUFMAN S.1975; J. BIOL. CHEM.; U.S.A.; DA. 1975; VOL. 250; NO 12; PP. 4782-4785; BIBL. 18 REF.Article

HYPERPHENYLALANINEMIA DUE TO DIHYDROPTERIDINE REDUCTASE DEFICIENCY: DIAGNOSIS BY MEASUREMENT OF OXIDIZED AND REDUCED PTERINS IN URINEMILSTIEN S; KAUFMAN S; SUMMER GK et al.1980; PEDIATRICS; USA; DA. 1980; VOL. 65; NO 4; PP. 806-810; BIBL. 25 REF.Article

THE MECHANISM OF THE IRREVERSIBLE INHIBITION OF RAT LIVER PHENYLALANINE HYDROXYLASE DUE TO TREATMENT WITH P-CHLOROPHENYLALANINE: THE LACK OF EFFECT ON TURNOVER OF PHENYLALANINE HYDROXYLASECHANG N; KAUFMAN S; MILSTIEN S et al.1979; J. BIOL. CHEM.; USA; DA. 1979; VOL. 254; NO 8; PP. 2665-2668; BIBL. 13 REF.Article

PARTIAL PURIFICATION AND CHARACTERIZATION OF RAT LIVER PHENYLALANINE HYDROXYLASE PHOSPHATASE.JEDLICKI E; KAUFMAN S; MILSTIEN S et al.1977; J. BIOL. CHEM.; U.S.A.; DA. 1977; VOL. 252; NO 21; PP. 7711-7714; BIBL. 11 REF.Article

The biosynthesis of tetrahydrobiopterin in rat brain: purification and characterization of 6-pyruvoyl tetrahydropterin (2'-oxo)reductaseMILSTIEN, S; KAUFMAN, S.The Journal of biological chemistry (Print). 1989, Vol 264, Num 14, pp 8066-8073, issn 0021-9258Article

HEPATIC PHENYLALANINE 4-MONOOXYGENASE IS A PHOSPHOPROTEIN.MILSTIEN S; ABITA JP; CHANG N et al.1976; PROC. NATION. ACAD. SCI. U.S.A.; U.S.A.; DA. 1976; VOL. 73; NO 5; PP. 1591-1593; BIBL. 14 REF.Article

Availability of tetrahydrobiopterin is not a factor in the inability to detect nitric oxide production by human macrophagesSAKAI, N; MILSTIEN, S.Biochemical and biophysical research communications (Print). 1993, Vol 193, Num 1, pp 378-383, issn 0006-291XArticle

The oxidation of apomorphine and other catechol compounds by horseradish peroxidase: relevance to the measurement of dihydropteridine reductase activityMILSTIEN, S; KAUFMAN, S.Biochimica et biophysica acta. 1987, Vol 923, Num 3, pp 333-338, issn 0006-3002Article

PHENYLKETONURIA DUE TO A DEFICIENCY OF DIHYDROPTERIDINE REDUCTASE.KAUFMAN S; HOLTZMAN NA; MILSTIEN S et al.1975; NEW ENGL. J. MED.; U.S.A.; DA. 1975; VOL. 293; NO 16; PP. 785-790; BIBL. 24 REF.Article

HYPERPHENYLALANINAEMIA DUE TO DIHYDROPTERIDINE REDUCTASE DEFICIENCYGROBE H; BARTHOLOME K; MILSTIEN S et al.1978; EUROP. J. PEDIATR.; DEU; DA. 1978; VOL. 129; NO 2; PP. 93-98; BIBL. 18 REF.Article

Immunological studies on the participation of 6-pyruvoyl tetrahydropterin (2'-oxo) reductase, an aldose reductase, in tetrahydrobiopterin biosynthesisMILSTIEN, S; KAUFMAN, S.Biochemical and biophysical research communications (Print). 1989, Vol 165, Num 2, pp 845-850, issn 0006-291XArticle

Conversion of 6-substituted tetrahydropterins to 7-isomers via phenylalanine hydroxylase-generated intermediatesDAVIS, M. D; KAUFMAN, S; MILSTIEN, S et al.Proceedings of the National Academy of Sciences of the United States of America. 1991, Vol 88, Num 2, pp 385-389, issn 0027-8424, 5 p.Article

Tetrahydrobiopterin biosynthesis defects examind in cytokine-stimulated fibroblastsMILSTIEN, S; KAUFMAN, S; SAKAI, N et al.Journal of inherited metabolic disease. 1993, Vol 16, Num 6, pp 975-981, issn 0141-8955Article

Studies on the interaction of a thiol-dependent hydrogen peroxide scavenging enzyme and phenylalanine hydroxylaseMILSTIEN, S; DORCHE, C; SEYMOUR KAUFMAN et al.Archives of biochemistry and biophysics (Print). 1990, Vol 282, Num 2, pp 346-351, issn 0003-9861, 6 p.Article

Tetrahydrobiopterin, the cofactor for aromatic amino acid hydroxylases, is synthesized by and regulates proliferation of erythroid cellsTANAKA, K; KAUFMAN, S; MILSTIEN, S et al.Proceedings of the National Academy of Sciences of the United States of America. 1989, Vol 86, Num 15, pp 5864-5867, issn 0027-8424, 4 p.Article

HYPERPHENYLALAMINEMIA DUE TO A DEFICIENCY OF BIOPTERIN. A VARIANT FORM OF PHENYLKETONURIAKAUFMAN S; BERLOW S; SUMMER GK et al.1978; NEW ENGL. J. MED.; USA; DA. 1978; VOL. 299; NO 13; PP. 673-679; BIBL. 26 REF.Article

Parallel induction of nitric oxide and tetrahydrobiopterin synthesis by cytokines in rat glial cellsSAKAI, N; KAUFMAN, S; MILSTIEN, S et al.Journal of neurochemistry. 1995, Vol 65, Num 2, pp 895-902, issn 0022-3042Article

Distribution of 4a-hydroxytetrahydropterin dehydratase in rat tissues : comparison with the aromatic amino acid hydroxylasesDAVIS, M. D; KAUFMAN, S; MILSTIEN, S et al.FEBS letters. 1992, Vol 302, Num 1, pp 73-76, issn 0014-5793Article

GTP cyclohydrolase I feedback regulatory protein is expressed in serotonin neurons and regulates tetrahydrobiopterin biosynthesisKAPATOS, G; HIRAYAMA, K; SHIMOJI, M et al.Journal of neurochemistry. 1999, Vol 72, Num 2, pp 669-675, issn 0022-3042Article

Cytokines stimulate GTP cyclohydrolase I gene expression in cultured human umbilical vein endothelial cellsKATUSIC, Z. S; STELTER, A; MILSTIEN, S et al.Arteriosclerosis, thrombosis, and vascular biology. 1998, Vol 18, Num 1, pp 27-32, issn 1079-5642Article

Tetrahydrobiopterin is required for cytokine-induced nitric oxide production in a murine macrophage cell line Raw 264°SAKAI, N; KAUFMAN, S; MILSTIEN, S et al.Molecular pharmacology. 1993, Vol 43, Num 1, pp 6-10, issn 0026-895XArticle

HYPERPHENYLALANINEMIA DUE TO DIHYDROPTERIDINE REDUCTASE DEFICIENCY. ASSAY OF THE ENZYME IN FIBROBLASTS FROM AFFECTED INFANTS, HETERIZYGOTES, AND IN NORMAL AMNIOTIC FLUID CELLS.MILSTIEN S; HOLTZMAN NA; O'FLYNN ME et al.1976; J. PEDIATR.; U.S.A.; DA. 1976; VOL. 89; NO 5; PP. 763-766; BIBL. 13 REF.Article

Expression and function of recombinant endothelial NO synthase in coronary artery smooth muscle cellsKULLO, I. J; SCHWARTZ, R. S; POMPILI, V. J et al.Arteriosclerosis, thrombosis, and vascular biology. 1997, Vol 17, Num 11, pp 2405-2412, issn 1079-5642Article