FK506 inhibits prostaglandin E₂ production from synovial cells by suppressing peripheral blood mononuclear cellsSASAKAWA, Tatsuya; SASAKAWA, Yuka; OHKUBO, Yoshitaka et al.International immunopharmacology. 2005, Vol 5, Num 7-8, pp 1291-1297, issn 1567-5769, 7 p.Article

Enzyme activities of the nitric oxide: cGMP pathway in corpus cavernosum isolated from middle-aged ratsHOSOGAI, Naomi; TAKAKURA, Shoji; MANDA, Toshitaka et al.European journal of pharmacology. 2003, Vol 473, Num 1, pp 65-70, issn 0014-2999, 6 p.Article

Role of cyclooxygenase-2, but not cyclooxygenase-1, on type II collagen-induced arthritis in DBA/1J miceOCHI, Takehiro; OHKUBO, Yoshitaka; MUTOH, Seitaro et al.Biochemical pharmacology. 2003, Vol 66, Num 6, pp 1055-1060, issn 0006-2952, 6 p.Article

Blockade of the antinociceptive effect of spinally administered kyotorphin by naltrindole in miceOCHI, Takehiro; OHKUBO, Yoshitaka; MUTOH, Seitaro et al.Neuroscience letters. 2002, Vol 322, Num 2, pp 95-98, issn 0304-3940Article

Combined treatment of quetiapine with haloperidol in animal models of antipsychotic effect and extrapyramidal side effects: comparison with risperidone and chlorpromazineTADA, Miho; SHIRAKAWA, Kiyoharu; MATSUOKA, Nobuya et al.Psychopharmacologia. 2004, Vol 176, Num 1, pp 94-100, issn 0033-3158, 7 p.Article

The spinal antinociceptive effect of kyotorphin in mice: involvement of the descending noradrenergic and serotonergic systemsOCHI, Takehiro; OHKUBO, Yoshitaka; MUTOH, Seitaro et al.Neuroscience letters. 2002, Vol 329, Num 2, pp 193-196, issn 0304-3940Article

Tacrolimus (FK506) has protective actions against murine bleomycin-induced acute lung injuriesKOSHIKA, Tadatsura; HIRAYAMA, Yoshitaka; OHKUBO, Yoshitaka et al.European journal of pharmacology. 2005, Vol 515, Num 1-3, pp 169-178, issn 0014-2999, 10 p.Article

Combination of a novel antidementia drug FK960 with donepezil synergistically improves memory deficits in ratsTOKITA, Kenichi; YAMAZAKI, Shunji; YAMAZAKI, Mayako et al.Pharmacology, biochemistry and behavior. 2002, Vol 73, Num 3, pp 511-519, issn 0091-3057, 9 p.Article

Mechanism of HDAC inhibitor FR235222-mediated IL-2 transcriptional repression in jurkat cellsMATSUOKA, Hideaki; FUJIMURA, Takao; MOD, Hiroaki et al.International immunopharmacology. 2007, Vol 7, Num 11, pp 1422-1432, issn 1567-5769, 11 p.Article

Calcineurin inhibitors exert rapid reduction of inflammatory pain in rat adjuvant-induced arthritisMAGARI, Katsue; MIYATA, Susumu; OHKUBO, Yoshitaka et al.British journal of pharmacology. 2003, Vol 139, Num 5, pp 927-934, issn 0007-1188, 8 p.Article

Differential effects of FK506 and methotrexate on inflammatory cytokine levels in rat adjuvant-induced arthritisMAGARI, Katsue; MIYATA, Susumu; NISHIGAKI, Fusako et al.Journal of rheumatology. 2003, Vol 30, Num 10, pp 2193-2200, issn 0315-162X, 8 p.Article

Phosphodiesterase type 5 inhibition ameliorates nephrotoxicity induced by cyclosporin A in spontaneous hypertensive ratsHOSOGAI, Naomi; TOMITA, Masayuki; HAMADA, Kaori et al.European journal of pharmacology. 2003, Vol 477, Num 2, pp 171-178, issn 0014-2999, 8 p.Article

Effects of FK228, a novel histone deacetylase inhibitor, on human lymphoma U-937 cells in vitro and in vivoSASAKAWA, Yuka; NAOE, Yoshinori; INOUE, Takeshi et al.Biochemical pharmacology. 2002, Vol 64, Num 7, pp 1079-1090, issn 0006-2952, 12 p.Article

Restoration of middle cerebral artery thrombosis by novel glycoprotein IIb/IIIa antagonist FK419 in guinea pigMORIGUCHI, Akira; MIHARA, Kayoko; AOKI, Toshiaki et al.European journal of pharmacology. 2004, Vol 498, Num 1-3, pp 179-188, issn 0014-2999, 10 p.Article

Topical application of FK506 (tacrolimus) ointment inhibits mite antigen-induced dermatitis by local action in NC/Nga miceSASAKAWA, Tatsuya; HIGASHI, Yasuyuki; SAKUMA, Shozo et al.International archives of allergy and immunology. 2004, Vol 133, Num 1, pp 55-63, issn 1018-2438, 9 p.Article

Intracerebroventricular injection of the antibiotic cefoselis produces convulsion in mice via inhibition of GABA receptorsYAMAZAKI, Shunji; MOCHIZUKI, Yoshitaka; TERAI, Takao et al.Pharmacology, biochemistry and behavior. 2002, Vol 74, Num 1, pp 53-59, issn 0091-3057, 7 p.Article

FK506 aerosol locally inhibits antigen-induced airway inflammation in guinea pigsMORISHITA, Yoshihiko; HIRAYAMA, Yoshitaka; MIYAYASU, Kikuo et al.International archives of allergy and immunology. 2005, Vol 136, Num 4, pp 372-378, issn 1018-2438, 7 p.Article

FK962, a novel enhancer of somatostatin release, exerts cognitive-enhancing actions in ratsTOKITA, Kenichi; INOUE, Tatsuo; YAMAZAKI, Shunji et al.European journal of pharmacology. 2005, Vol 527, Num 1-3, pp 111-120, issn 0014-2999, 10 p.Article

FK419, a novel nonpeptide GPIIb/IIIa antagonist, restores microvascular patency and improves outcome in the guinea-pig middle cerebral artery thrombotic occlusion model : comparison with tirofibanMORIGUCHI, Akira; MAEDA, Masashi; MIHARA, Kayoko et al.Journal of cerebral blood flow and metabolism. 2005, Vol 25, Num 1, pp 75-86, issn 0271-678X, 12 p.Article

Choleretic actions of insulin-like growth factor-I, prednisolone, and ursodeoxycholic acid in ratsMABUCHI, Miyuki; KAWAMURA, Ikuo; FUSHIMI, Mariko et al.Digestive diseases and sciences. 2003, Vol 48, Num 7, pp 1398-1405, issn 0163-2116, 8 p.Article

Effect of FK3657, a non-peptide bradykinin B₂ receptor antagonist, on allergic airway disease modelsHIRAYAMA, Yoshitaka; MIYAYASU, Kikuo; YAMAGAMI, Kaoru et al.European journal of pharmacology. 2003, Vol 467, Num 1-3, pp 197-203, issn 0014-2999, 7 p.Article

Effects of FK228, a novel histone deacetylase inhibitor, on tumor growth and expression of p21 and c-myc genes in vivoSASAKAWA, Yuka; NAOE, Yoshinori; INOUE, Takeshi et al.Cancer letters. 2003, Vol 195, Num 2, pp 161-168, issn 0304-3835, 8 p.Article

Effects of FK506 (tacrolimus hydrate) on chronic oxazolone-induced dermatitis in ratsFUJII, Yasutomo; TAKEUCHI, Hiroko; TANAKA, Keiko et al.European journal of pharmacology. 2002, Vol 456, Num 1-3, pp 115-121, issn 0014-2999, 7 p.Article

Prevention of progressive joint destruction in adjuvant induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR217840ISHIKAWA, Takeshi; NISHIGAKI, Fusako; MUTOH, Seitaro et al.European journal of pharmacology. 2005, Vol 508, Num 1-3, pp 239-247, issn 0014-2999, 9 p.Article

Characterization of the anti-platelet actions of FK419, a novel non-peptide antagonist of platelet GPIIb/IIIaMIHARA, Kayoko; AOKI, Toshiaki; MUTOH, Seitaro et al.Drug development research. 2004, Vol 61, Num 4, pp 233-241, issn 0272-4391, 9 p.Article