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kw.\*:("Merbarone")

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Initial mechanistic studies with merbarone (NSC 336628)COONEY, D. A; COVEY, J. M; KANG, G. J et al.Biochemical pharmacology. 1985, Vol 34, Num 18, pp 3395-3398, issn 0006-2952Article

Quantitation of merbarone in human plasma by high-performance liquid chromatographySTEVENS, Y.-W; WALSH, T. D; FANUCCHI, M. P et al.Journal of chromatography. 1987, Vol 416, Num 1, pp 203-206, issn 0021-9673Article

Etoposide and merbarone are clastogenic and aneugenic in the mouse bone marrow micronucleus test complemented by fluorescence in situ hybridization with the mouse minor satellite DNA probeATTIA, S. M; KLIESCH, U; SCHRIEVER-SCHWEMMER, G et al.Environmental and molecular mutagenesis (Print). 2003, Vol 41, Num 2, pp 99-103, issn 0893-6692, 5 p.Article

Evaluation of merbarone (NSC 336628) in disseminated malignant melanomaSLAVIK, M; LIU, P. Y; KRAUT, E. H et al.Investigational new drugs. 1995, Vol 13, Num 2, pp 143-147, issn 0167-6997Article

Hepatoma/merbarone : a Southwest Oncology Group studyPOPLIN, E. A; TANGEN, C. M; HARVEY, W. H et al.Investigational new drugs. 1994, Vol 12, Num 4, pp 337-340, issn 0167-6997Article

Phase II study of taxol, merbarone, and piroxantrone in stage IV non-small-cell lung cancer : the eastern cooperative oncology group resultsCHANG, A. Y; KIM, K; GLICK, J et al.Journal of the National Cancer Institute. 1993, Vol 85, Num 5, pp 388-394, issn 0027-8874Article

Distribution of [2-14C]merbarone in mice by autoradiography of whole-body cryosectionsKEMMENOE, B. H; MALSPEIS, L.Cancer research (Baltimore). 1987, Vol 47, Num 4, pp 1135-1142, issn 0008-5472Article

Evidence from studies with intact mammalian cells that merbarone and bis(dioxopiperazine)s are topoisomerase II poisonsSNYDER, Ronald D.Drug and chemical toxicology (New York, NY. 1978). 2003, Vol 26, Num 1, pp 15-22, issn 0148-0545, 8 p.Article

G2 arrest in response to topoisomerase II inhibitors: The role of p53CLIFFORD, Brad; BELJIN, Milos; STARK, George R et al.Cancer research (Baltimore). 2003, Vol 63, Num 14, pp 4074-4081, issn 0008-5472, 8 p.Article

Novel actions of inhibitors of DNA topoisomerase II in drug-resistant tumor cellsBECK, W. T; RYUNGSA KIM; MEI CHEN et al.Cancer chemotherapy and pharmacology. 1994, Vol 34, pp S14-S18, issn 0344-5704, SUPConference Paper

Induction of profound hypouricemia by a non-sedating thiobarbiturateWARRELL, R. P. JR; MUNDI, J; STEVENS, Y.-W et al.Metabolism, clinical and experimental. 1989, Vol 38, Num 6, pp 550-554, issn 0026-0495Article

Characterization of novel human leukemic cell lines selected for resistance to merbarone, a catalytic inhibitor of DNA topoisomerase IIKUSUMOTO, H; RODGERS, Q. E; BOEGE, F et al.Cancer research (Baltimore). 1996, Vol 56, Num 11, pp 2573-2583, issn 0008-5472Article

Effects of DNA topoisomerase II inhibitors on human bone marrow progenitor cellsFRANCIS, G. E; TEJEDOR, M. C; BERNEY, J. J et al.Leukemia. 1994, Vol 8, Num 1, pp 121-128, issn 0887-6924Article

Teniposide-resistant CEM cells, which express mutant DNA topoisomerase IIα, when treated with non-complex-stabilizing inhibitors of the enzyme, display no cross-resistance and reveal aberrant functions of the mutant enzymeMEI CHEN; BECK, W. T.Cancer research (Baltimore). 1993, Vol 53, Num 24, pp 5946-5953, issn 0008-5472Article

Concurrent determination of merbarone and its urinary metabolites by reversed-phase HPLC with precolumn phenolic acetylationSUPKO, J. G; MALSPEIS, L.Journal of liquid chromatography. 1991, Vol 14, Num 11, pp 2169-2188, issn 0148-3919Article

Phase I clinical and pharmacological study of merbaroneDIMAGGIO, J. J; WARRELL, R. P. JR; YOUNG, C. W et al.Cancer research (Baltimore). 1990, Vol 50, Num 4, pp 1151-1155, issn 0008-5472Article

Collateral sensitivity to the bisdioxopiperazine dexrazoxane (ICRF-187) in etoposide (VP-16)-resistant human leukemia K562 cellsFATTMAN, C. L; ALLAN, W. P; HASINOFF, B. B et al.Biochemical pharmacology. 1996, Vol 52, Num 4, pp 635-642, issn 0006-2952Article

Phase II trial of merbarone in pancreatic carcinoma : a Southwest oncology group studyKRAUT, E. H; FLEMING, T; MACDONALD, J. S et al.American journal of clinical oncology. 1993, Vol 16, Num 4, pp 327-328, issn 0277-3732Article

Cleavage of the MLL gene by activators of apoptosis is independent of topoisomerase II activityBETTI, C. J; VILLALOBOS, M. J; JIANG, Q et al.Leukemia. 2005, Vol 19, Num 12, pp 2289-2295, issn 0887-6924, 7 p.Article

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