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Results 1 to 25 of 684

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Predictive Physiologically Based Pharmacokinetic Model for Antibody-Directed Enzyme Prodrug TherapyLANYAN FANG; DUXIN SUN.Drug metabolism and disposition. 2008, Vol 36, Num 6, pp 1153-1165, issn 0090-9556, 13 p.Article

Physiologically Based Pharmacokinetic (PBPK) Modeling in ChildrenBARRETT, J. S; DELLA CASA ALBERIGHI, O; LÄER, S et al.Clinical pharmacology and therapeutics. 2012, Vol 92, Num 1, pp 40-49, issn 0009-9236, 10 p.Article

Biologically-based models of dioxin pharmacokineticsBUCKLEY, L. A.Toxicology (Amsterdam). 1995, Vol 102, Num 1-2, pp 125-131, issn 0300-483XConference Paper

Perspectives on collaboration and infrastructures development, academia, and industryO'FLAHERTY, E. J.Toxicology letters. 1995, Vol 79, Num 1-3, pp 297-298, issn 0378-4274Conference Paper

Incorporation of first-order uptake rate constants from simple mammillary models into blood-flow limited physiological pharmacokinetic models via extraction efficienciesROTH, W. L; WEBER, L. W. D; ROZMAN, K. K et al.Pharmaceutical research. 1995, Vol 12, Num 2, pp 263-269, issn 0724-8741Article

Evaluation of physiologically based pharmacokinetic models for use in risk assessment‡CHIU, Weihsueh A; BARON, Hugh A; DEWOSKIN, Robert S et al.Journal of applied toxicology. 2007, Vol 27, Num 3, pp 218-237, issn 0260-437X, 20 p.Article

Bayesian analysis of physiologically based toxicokinetic and toxicodynamic modelsHACK, C. Eric.Toxicology (Amsterdam). 2006, Vol 221, Num 2-3, pp 241-248, issn 0300-483X, 8 p.Article

A physiologically based pharmacokinetic model for retinoic acid and its metabolitesCLEWEL, H. J; ANDERSEN, M. E; WILLS, R. J et al.Journal of the American Academy of Dermatology. 1997, Vol 36, Num 3, pp S77-S85, issn 0190-9622, 2Article

A generic biokinetic model for noble gases with application to radonLEGGETT, Rich; MARSH, James; GREGORATTO, Demetrio et al.Journal of radiological protection (Print). 2013, Vol 33, Num 2, pp 413-432, issn 0952-4746, 20 p.Article

Sensitivity analysis of pharmacokinetic and pharmacodynamic systems : I. A structural approach to sensitivity analysis of physiologically based pharmacokinetic modelsNESTOROV, Ivan A.Journal of pharmacokinetics and biopharmaceutics. 1999, Vol 27, Num 6, pp 577-596, issn 0090-466XArticle

A physiological model for the estimation of the fraction dose absorbed in humansWILLMANN, Stefan; SCHMITT, Walter; KELDENICH, Jörg et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 16, pp 4022-4031, issn 0022-2623, 10 p.Article

Metabolic modeling: a tool of drug discovery in the post-genomic eraVOIT, Eberhard O.Drug discovery today. 2002, Vol 7, Num 11, pp 621-628, issn 1359-6446Article

Achieving credibility in risk assessment modelsKOHN, M. C.Toxicology letters. 1995, Vol 79, Num 1-3, pp 107-114, issn 0378-4274Conference Paper

Applications and prospects for physiologically based pharmacokinetic (PB-PK) models involving pharmaceutical agentsSUZUKI, H; IWATSUBO, T; SUGIYAMA, Y et al.Toxicology letters. 1995, Vol 82-83, pp 349-355, issn 0378-4274Conference Paper

Structural identifiability of physiologically based pharmacokinetic modelsYATES, James W. T.Journal of pharmacokinetics and pharmacodynamics (Print). 2006, Vol 33, Num 4, pp 421-439, issn 1567-567X, 19 p.Article

Effects of the structure of a toxicokinetic model of butadiene inhalation exposure on computed production of carcinogenic intermediatesKOHN, M. C; MELNICK, R. L.Toxicology (Amsterdam). 1996, Vol 113, Num 1-3, pp 31-39, issn 0300-483XConference Paper

Inhalation anesthesia using physiologically based pharmacokinetic modelsFISEROVA-BERGEROVA, V.Drug metabolism reviews (Softcover ed.). 1992, Vol 24, Num 4, pp 531-557, issn 0360-2532Article

Partitioning of polar and non-polar neutral organic chemicals into human and cow milkGEISLER, Anett; ENDO, Satoshi; GOSS, Kai-Uwe et al.Environment international. 2011, Vol 37, Num 7, pp 1253-1258, issn 0160-4120, 6 p.Article

PBPK Model Describes the Effects of Comedication and Genetic Polymorphism on Systemic Exposure of DrugsThat Undergo Multiple Clearance PathwaysVIEIRA, Md L. T; KIM, M.-J; APPARAJU, S et al.Clinical pharmacology and therapeutics. 2014, Vol 95, Num 5, pp 550-557, issn 0009-9236, 8 p.Article

Physiologically based pharmacokinetic modelling of human exposure to 2-butoxyethanolFRANKS, S. J; SPENDIFF, M. K; COCKER, J et al.Toxicology letters. 2006, Vol 162, Num 2-3, pp 164-173, issn 0378-4274, 10 p.Conference Paper

Physiologically based modeling of 1,2,4-trimethylbenzene inhalation toxicokineticsJÄRNBERG, J; JOHANSON, G.Toxicology and applied pharmacology. 1999, Vol 155, Num 3, pp 203-214, issn 0041-008XArticle

Physiologically based models for bone-seeking elements. V: Lead absorption and disposition in childhoodO'FLAHERTY, E. J.Toxicology and applied pharmacology. 1995, Vol 131, Num 2, pp 297-308, issn 0041-008XArticle

Summary of panel discussion on the 'advantages/limitations/uncertainties in the use of physiologically based pharmacokinetic and pharmacodynamic models in hazard identification and risk assessment of toxic substances'FREDERICK, C. B.Toxicology letters. 1995, Vol 79, Num 1-3, pp 201-206, issn 0378-4274Conference Paper

The use of physiologically-based pharmacokinetic/pharmacodynamic dosimetry models for chemical mixturesYANG, R. S. H; EL-MASRI, H. A; THOMAS, R. S et al.Toxicology letters. 1995, Vol 82-83, pp 497-504, issn 0378-4274Conference Paper

Biological and physiological factors involved in disposition of dioxin and related compoundsMILLS, J. J; GARGAS, M. L; ANDERSEN, M. E et al.Chemosphere (Oxford). 1992, Vol 25, Num 1-2, pp 3-6, issn 0045-6535Conference Paper

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