The scholar as storyteller: Essays in honor of Harold E. ScheubCANCEL, Robert; COSENTINO, Donald; WENDLAND, Ernst R et al.Research in African literatures (Print). 2006, Vol 37, Num 2, pp 1-123, issn 0034-5210, 123 p.Article

Gibbs free energy of formation of zircon from measurement of solubility in H₂ONEWTON, Robert C; MANNING, Craig E; HANCHAR, John M et al.Journal of the American Ceramic Society. 2005, Vol 88, Num 7, pp 1854-1858, issn 0002-7820, 5 p.Article

Severe retinal degeneration associated with disruption of semaphorin 4ARICE, Dennis S; WENHU HUANG; ZAMBROWICZ, Brian P et al.Investigative ophthalmology & visual science. 2004, Vol 45, Num 8, pp 2767-2777, issn 0146-0404, 11 p.Article

α,β-Cyclic-β-benzamido hydroxamic acids : Novel templates for the design, synthesis, and evaluation of selective inhibitors of TNF-α converting enzyme (TACE)OTT, Gregory R; ASAKAWA, Naoyuki; DECICCO, Carl P et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 2, pp 694-699, issn 0960-894X, 6 p.Article

Pharmacokinetics and pharmacodynamics of DPC 333 (2R)-2-((3R)-3 -amino -3{4 -[2 -methyl -4 -quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl -n -hydroxy -4 -methylpentanamide , a potent and selective inhibitor of tumor necrosis factor α-Converting enzyme in rodents, dogs, chimpanzees, and humansMINGXIN QIAN; BAI, Stephen A; YUZHONG DENG et al.Drug metabolism and disposition. 2007, Vol 35, Num 10, pp 1916-1925, issn 0090-9556, 10 p.Article

Sultam hydroxamates as novel matrix metalloproteinase inhibitorsCHERNEY, Robert J; MO, Ruowei; NEWTON, Robert C et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 12, pp 2981-2983, issn 0022-2623, 3 p.Article

Design, synthesis, and evaluation of benzothiadiazepine hydroxamates as selective tumor necrosis factor-α converting enzyme inhibitorsCHERNEY, Robert J; DUAN, James J.-W; MINGXIN QIAN et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 10, pp 1811-1823, issn 0022-2623, 13 p.Article

Discovery of N-hydroxy-2-(2-oxo-3-pyrrolidinyl)acetamides as potent and selective inhibitors of tumor necrosis factor-α converting enzyme (TACE)DUAN, James J.-W; ZHONGHUI LU; NEWTON, Robert C et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 12, pp 2035-2040, issn 0960-894X, 6 p.Article

Induction of aggrecanase 1 (ADAM-TS4) by interleukin-1 occurs through activation of constitutively produced proteinPRATTA, Michael A; SCHERLE, Peggy A; GENGJIE YANG et al.Arthritis and rheumatism. 2003, Vol 48, Num 1, pp 119-133, issn 0004-3591, 15 p.Article

Discovery of macrocyclic hydroxamic acids containing biphenylmethyl derivatives at P1', a series of selective TNF-α converting enzyme inhibitors with potent cellular activity in the inhibition of TNF-α releaseXUE, Chu-Biao; XIAOHUA HE; NEWTON, Robert C et al.Journal of medicinal chemistry (Print). 2001, Vol 44, Num 21, pp 3351-3354, issn 0022-2623Article

Potent, exceptionally selective, orally bioavailable inhibitors of TNF-α Converting Enzyme (TACE) : Novel 2-substituted-1H-benzo[d]imidazol-1-ylmethylbenzamide P1' substituentsOTT, Gregory R; ASAKAWA, Naoyuki; TRZASKOS, James M et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 5, pp 1577-1582, issn 0960-894X, 6 p.Article

Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-a converting enzyme (TACE) : Discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1' substituentsZHONGHUI LU; OTT, Gregory R; DUAN, James J.-W et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 6, pp 1958-1962, issn 0960-894X, 5 p.Article

Synthesis and structure-activity relationship of a novel, achiral series of TNF-α converting enzyme inhibitorsGILMORE, John L; KING, Bryan W; TRZASKOS, James M et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 10, pp 2699-2704, issn 0960-894X, 6 p.Article

2,4-Disubstituted piperidines as selective CC chemokine receptor 3 (CCR3) antagonists : Synthesis and selectivityWATSON, Paul S; BIN JIANG; NEWTON, Robert C et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 21, pp 5695-5699, issn 0960-894X, 5 p.Article

Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potencyDE LUCCA, George V; UI TAE KIM; WACKER, Dean A et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 6, pp 2194-2211, issn 0022-2623, 18 p.Article

Synthesis and structure-activity relationship of a novel sulfone series of TNF-α converting enzyme inhibitorsXUE, Chu-Biao; CHEN, Xiao-Tao; VADDI, Krishna et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 17, pp 4453-4459, issn 0960-894X, 7 p.Article

Discovery of γ-lactam hydroxamic acids as selective inhibitors of tumor necrosis factor a converting enzyme: Design, synthesis, and structure: Activity relationshipsDUAN, James J.-W; LIHUA CHEN; CHRIST, David D et al.Journal of medicinal chemistry (Print). 2002, Vol 45, Num 23, pp 4954-4957, issn 0022-2623, 4 p.Article

Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor a release in vitro and in vivoXUE, Chu-Biao; VOSS, Matthew E; WANG, Li et al.Journal of medicinal chemistry (Print). 2001, Vol 44, Num 16, pp 2636-2660, issn 0022-2623Article

Phase 2 study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including postmyeloproliferative neoplasm acute myeloid leukemiaEGHTEDAR, Alireza; VERSTOVSEK, Srdan; SCHERLE, Peggy A et al.Blood. 2012, Vol 119, Num 20, pp 4614-4618, issn 0006-4971, 5 p.Article

Design and synthesis of novel CCR2 antagonists: Investigation of non-aryl/heteroaryl binding motifsTRUJILLO, John I; WEI HUANG; NEWTON, Robert C et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 6, pp 1827-1831, issn 0960-894X, 5 p.Article

Discovery of β-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitorsDUAN, James J.-W; LIHUA CHEN; TRZASKOS, James M et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 1, pp 241-246, issn 0960-894X, 6 p.Article

Α,β -Cyclic-β -benzamido hydroxamic acids : Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-a converting enzyme (TACE)OTT, Gregory R; ASAKAWA, Naoyuki; SCHOLZ, Thomas et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 4, pp 1288-1292, issn 0960-894X, 5 p.Article

A new 4-(2-methylquinolin-4-ylmethyl)phenyl P1' group for the β-amino hydroxamic acid derived TACE inhibitorsCHEN, Xiao-Tao; GHAVIMI, Bahman; RIBADENEIRA, Maria D et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 7, pp 1865-1870, issn 0960-894X, 6 p.Article

Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancerFRIDMAN, Jordan S; CAULDER, Eian; GRANDIS, Jennifer R et al.Clinical cancer research. 2007, Vol 13, Num 6, pp 1892-1902, issn 1078-0432, 11 p.Article

Rational design, synthesis and structure-activity relationships of a cyclic succinate series of TNF-α converting enzyme inhibitors. Part 2: Lead optimizationXUE, Chu-Biao; XIAOHUA HE; CHRIST, David D et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 24, pp 4299-4304, issn 0960-894X, 6 p.Article