Clinical studies in patients with Castleman's disease, Crohn's disease, and rheumatoid arthritis in JapanNISHIMOTO, Norihiro.Clinical reviews in allergy and immunology. 2005, Vol 28, Num 3, pp 221-229, issn 1080-0549, 9 p.Article

Cytokine signal regulation and autoimmune disordersNISHIMOTO, Norihiro.Autoimmunity (Print). 2005, Vol 38, Num 5, pp 359-367, issn 0891-6934, 9 p.Article

The Blockade of IL-6 Signaling in Rational Drug DesignADACHI, Yasuo; YOSHIO-HOSHINO, Naoko; NISHIMOTO, Norihiro et al.Current pharmaceutical design. 2008, Vol 14, Num 12, pp 1217-1224, issn 1381-6128, 8 p.Article

Successful Treatment of a Patient With Takayasu Arteritis Using a Humanized Anti-Interleukin-6 Receptor AntibodyNISHIMOTO, Norihiro; NAKAHARA, Hideko; YOSHIO-HOSHINO, Naoko et al.Arthritis and rheumatism. 2008, Vol 58, Num 4, pp 1197-1200, issn 0004-3591, 4 p.Article

VEGF Targeting in Mesotheliomas Using an Interleukin-6 Signal Inhibitor Based on Adenovirus Gene DeliveryADACHI, Yasuo; YOSHIO-HOSHINO, Naoko; AOKI, Chieko et al.Anticancer research. 2010, Vol 30, Num 6, pp 1947-1952, issn 0250-7005, 6 p.Article

Interleukin-6 induces both cell growth and VEGF production in malignant mesotheliomasADACHI, Yasuo; AOKI, Chieko; YOSHIO-HOSHINO, Naoko et al.International journal of cancer. 2006, Vol 119, Num 6, pp 1303-1311, issn 0020-7136, 9 p.Article

Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritisNAKAHARA, Hideko; JIAN SONG; SUGIMOTO, Masamichi et al.Arthritis and rheumatism. 2003, Vol 48, Num 6, pp 1521-1529, issn 0004-3591, 9 p.Article

Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman diseaseNISHIMOTO, Norihiro; TERAO, Kimio; MIMA, Toru et al.Blood. 2008, Vol 112, Num 10, pp 3859-3864, issn 0006-4971, 6 p.Article

Humanized monoclonal anti-interleukin-6 receptor antibody for treatment of intractable adult-onset Still's diseaseIWAMOTO, Masahiro; NARA, Hiroyuki; HIRATA, Daisuke et al.Arthritis and rheumatism. 2002, Vol 46, Num 12, pp 3388-3389, issn 0004-3591, 2 p.Article

Establishment of a new lnterleukin-6 (IL-6) receptor inhibitor applicable to the gene therapy for IL-6-dependent tumorYOSHIO-HOSHINO, Naoko; ADACHI, Yasuo; AOKI, Chieko et al.Cancer research (Baltimore). 2007, Vol 67, Num 3, pp 871-875, issn 0008-5472, 5 p.Article

Anti-interleukin 6 receptor antibody inhibits murine AA-amyloidosisMIHARA, Masahiko; SHIINA, Masashi; NISHIMOTO, Norihiro et al.Journal of rheumatology. 2004, Vol 31, Num 6, pp 1132-1138, issn 0315-162X, 7 p.Article

Effect of interleukin-6 receptor blockage on renal injury in apolipoprotein E-deficient miceTOMIYAMA-HANAYAMA, Mari; RAKUGI, Hiromi; NISHIMOTO, Norihiro et al.American journal of physiology. Renal physiology. 2009, Vol 66, Num 3, issn 1931-857X, F679-F684Article

Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis : a randomised, double-blind, placebo-controlled, withdrawal phase III trial. CommentaryBONGARTZ, Tim; YOKOTA, Shumpei; MIYOSHI, Mari et al.Lancet (British edition). 2008, Vol 371, Num 9617, issn 0140-6736, 961-963, 998-1006 [12 p.]Article

Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: A multicenter, double-blind, placebo-controlled trialNISHIMOTO, Norihiro; YOSHIZAKI, Kazuyuki; MIYASAKA, Nobuyuki et al.Arthritis and rheumatism. 2004, Vol 50, Num 6, pp 1761-1769, issn 0004-3591, 9 p.Article

Toxicity, pharmacokinetics, and dose-finding study of repetitive treatment with the humanized anti-interleukin 6 receptor antibody MRA in rheumatoid arthritis. Phase I/II clinical studyNISHIMOTO, Norihiro; YOSHIZAKI, Kazuyuki; KISHIMOTO, Tadamitsu et al.Journal of rheumatology. 2003, Vol 30, Num 7, pp 1426-1435, issn 0315-162X, 10 p.Article

Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAL) : evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumabNISHIMOTO, Norihiro; HASHIMOTO, Jun; MIYASAKA, Nobuyuki et al.Annals of the rheumatic diseases. 2007, Vol 66, Num 9, pp 1162-1167, issn 0003-4967, 6 p.Article

Enhanced production of osteopontin in multiple myeloma: clinical and pathogenic implicationsSAEKI, Yukihiko; MIMA, Toru; KATADA, Yoshinori et al.British journal of haematology. 2003, Vol 123, Num 2, pp 263-270, issn 0007-1048, 8 p.Article

Humanized antibody to human interleukin-6 receptor inhibits the development of collagen arthritis in cynomolgus monkeysMIHARA, Masahiko; KOTOH, Masao; TAKEDA, And Yasuhisa et al.Clinical immunology (Orlando, Fla. Print). 2001, Vol 98, Num 3, pp 319-326, issn 1521-6616Article

Interleukin-6 Modulates Graft-versus-Host Responses after Experimental Allogeneic Bone Marrow TransplantationTAWARA, Isao; KOYAMA, Motoko; MALTER, Chelsea et al.Clinical cancer research (Print). 2011, Vol 17, Num 1, pp 77-88, issn 1078-0432, 12 p.Article

Anti-interleukin-6 receptor antibody therapy favors adrenal androgen secretion in patients with rheumatoid arthritis : A randomized, double-blind, placebo-controlled studySTRAUB, Rainer H; HÄRLE, Peter; YAMANA, Seizo et al.Arthritis and rheumatism. 2006, Vol 54, Num 6, pp 1778-1785, issn 0004-3591, 8 p.Article

Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman diseaseNISHIMOTO, Norihiro; KANAKURA, Yuzuru; HARA, Masamichi et al.Blood. 2005, Vol 106, Num 8, pp 2627-2632, issn 0006-4971, 6 p.Article

Human interleukin-6 induces human herpesvirus-8 replication in a body cavity-based lymphoma cell lineJIAN SONG; OHKURA, Takako; SUGIMOTO, Masamichi et al.Journal of medical virology. 2002, Vol 68, Num 3, pp 404-411, issn 0146-6615, 8 p.Article