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Synthesis and biological activity of 5-styryl and 5-phenethyl-substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indolesIVACHTCHENKO, Alexandre V; FROLOV, Eugen B; MITKIN, Oleg D et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 1, pp 78-82, issn 0960-894X, 5 p.Article

Screening of 64 Tryptamines at NMDA, 5-HT1A, and 5-HT2A Receptors: A Comparative Binding and Modeling StudyBERGER, M. L; PALANGSUNTIKUL, R; REBERNIK, P et al.Current medicinal chemistry. 2012, Vol 19, Num 18, pp 3044-3057, issn 0929-8673, 14 p.Article

New imidazoline/α2-adrenoceptors affecting compounds—4(5)—(2—aminoethyl)imidazoline (dihydrohistamine) derivatives. Synthesis and receptor affinity studiesTREDER, Adam P; ANDRUSZKIEWICZ, Ryszard; ZGODA, Włodzimierz et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 1, pp 156-167, issn 0968-0896, 12 p.Article

Synthesis of 4-(aminoalkyl) substituted 1,3-dioxanes as potent NMDA and σ receptor antagonistsUTECH, Tina; KÖHLER, Jens; WÜNSCH, Bernhard et al.European journal of medicinal chemistry. 2011, Vol 46, Num 6, pp 2157-2169, issn 0223-5234, 13 p.Article

A rationale for the activity profile of arylpiperazinylthioalkyls as 5-HT1A-serotonin and α1-adrenergic receptor ligandsBRIJ KISHORE SHARMA; SARBHAI, Kirti; SINGH, Prithvi et al.European journal of medicinal chemistry. 2010, Vol 45, Num 5, pp 1927-1934, issn 0223-5234, 8 p.Article

Synthesis and in vitro binding studies of piperazine-alkyl-naphthamides: Impact of homology and sulphonamide/carboxamide bioisosteric replacement on the affinity for 5-HT1A, α2A, D4.2, D3 and D2L receptorsRESIMONT, Mélissa; LIEGEOIS, Jean-François.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 17, pp 5199-5202, issn 0960-894X, 4 p.Article

Synthesis and monoamine transporter affinity of 3α-arylmethoxy-3β-arylnortropanesKAUR, Harneet; IZENWASSER, Sari; VERMA, Abha et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 24, pp 6865-6868, issn 0960-894X, 4 p.Article

1-(2-Phenoxyphenyl)methanamines : SAR for dual serotonin/noradrenaline reuptake inhibition, metabolic stability and hERG affinityWHITLOCK, Gavin A; BLAGG, Julian; FISH, Paul V et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 2, pp 596-599, issn 0960-894X, 4 p.Article

Pyridyl-phenyl ether monoamine reuptake inhibitors : Impact of lipophilicity on dual SNRI pharmacology and off-target promiscuityWHITLOCK, Gavin A; FISH, Paul V; FRAY, M. Jonathan et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 9, pp 2896-2899, issn 0960-894X, 4 p.Article

New 4-(4-methyl-phenyl)phthalazm-1(2H)-one derivatives and their effects on α-receptorsSTRAPPAGHETTI, Giovannella; BRODI, Chiara; GIANNACCINI, Gino et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 10, pp 2575-2579, issn 0960-894X, 5 p.Article

QSAR study for a novel series of ortho monosubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101FUMAGALLI, Laura; BOLCHI, Cristiano; COLLEONI, Simona et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 7, pp 2547-2559, issn 0968-0896, 13 p.Article

Dr4004, a putative 5-HT7 receptor antagonist, also has functional activity at the dopamine D2 receptorKOGAN, Helen A; MARSDEN, Charles A; FONE, Kevin C. F et al.European journal of pharmacology. 2002, Vol 449, Num 1-2, pp 105-111, issn 0014-2999Article

Behavioral evidence for interactions between a hallucinogenic drug and group II metabotropic glutamate receptorsGEWIRTZ, Jonathan C; MAREK, Gerard J.Neuropsychopharmacology (New York, NY). 2000, Vol 23, Num 5, pp 569-576, issn 0893-133XArticle

The structural requirements for phorbol esters to enhance serotonin and acetylcholine release from rat brain cortexIANNAZZO, L; KOTSONIS, P; MAJEWSKI, H et al.British journal of pharmacology. 1999, Vol 127, Num 5, pp 1177-1189, issn 0007-1188Article

Further SAR study on 11-O-substituted aporphine analogues: Identification of highly potent dopamine D3 receptor ligandsNA YE; QIANQIAN WU; LIYUAN ZHU et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 6, pp 1999-2008, issn 0968-0896, 10 p.Article

1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure-affinity/activity relationship at α1-adrenoceptor subtypes and at 5-HT1A receptorsFRANCHINI, Silvia; PRANDI, Adolfo; CICHERO, Elena et al.European journal of medicinal chemistry. 2010, Vol 45, Num 9, pp 3740-3751, issn 0223-5234, 12 p.Article

Synthesis and structure-activity studies of benzyl ester meperidine and normeperidine derivatives as selective serotonin transporter ligandsXIAOBO GU; IZENWASSER, Sari; WADE, Dean et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 23, pp 8356-8364, issn 0968-0896, 9 p.Article

An Overview on Benzylisoquinoline Derivatives with Dopaminergic and Serotonergic ActivitiesCABEDO, N; BERENGUER, I; FIGADERE, B et al.Current medicinal chemistry. 2009, Vol 16, Num 19, pp 2441-2467, issn 0929-8673, 27 p.Article

Chemical Interactions with Pyramidal Neurons in Layer 5 of the Cerebral Cortex: Control of Pain and AnxietyADAMS, J. D.Current medicinal chemistry. 2009, Vol 16, Num 27, pp 3476-3479, issn 0929-8673, 4 p.Article

From the Selective Serotonin Transporter Inhibitor Citalopram to the Selective Norepinephrine Transporter Inhibitor Talopram : Synthesis and Structure-Activity Relationship StudiesEILDAL, Jonas N. N; ANDERSEN, Jacob; KRISTENSEN, Anders S et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 10, pp 3045-3048, issn 0022-2623, 4 p.Article

Synthesis and biological affinity of new imidazo-and indol-arylpiperazine derivatives : Further validation of a pharmacophore model for α1-adrenoceptor antagonistsSTRAPPAGHETTI, Giovannella; MASTRINI, Luciano; LUCACCHINI, Antonio et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 18, pp 5140-5145, issn 0960-894X, 6 p.Article

Synthesis and pharmacological investigation of novel 2-aminothiazole-privileged aporphinesZHILI LIU; XUETAO CHEN; LEIPING YU et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 14, pp 6675-6681, issn 0968-0896, 7 p.Article

Total Synthesis and Biological Evaluation of the Marine Bromopyrrole Alkaloid Dispyrin : Elucidation of Discrete Molecular Targets with Therapeutic PotentialKENNEDY, J. Phillip; BROGAN, John T; LINDSLEY, Craig W et al.Journal of natural products (Print). 2008, Vol 71, Num 10, pp 1783-1786, issn 0163-3864, 4 p.Article

Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitorsKEITH, John M; GOMEZ, Leslie A; LOVENBERG, Timothy W et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 9, pp 2603-2607, issn 0960-894X, 5 p.Article

Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the position of the amide on the affinity for D2L, D4.2, and 5-HT2A receptorsCARATO, Pascal; GRAULICH, Amaury; JENSEN, Niels et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 6, pp 1565-1569, issn 0960-894X, 5 p.Article

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