Molecular Pathways: How Can BRCA-Mutated Tumors Become Resistant to PARP Inhibitors?BOUWMAN, Peter; JONKERS, Jos.Clinical cancer research (Print). 2014, Vol 20, Num 3, pp 540-547, issn 1078-0432, 8 p.Article

Overlap of the gene encoding the novel poly(ADP-ribose) polymerase Parp10 with the plectin 1 gene and common use of exon sequencesLESNIEWICZ, Krzysztof; LÜSCHER-FIRZLAFF, Juliane; POREBA, Elzbieta et al.Genomics (San Diego, Calif.). 2005, Vol 86, Num 1, pp 38-46, issn 0888-7543, 9 p.Article

Targeting DNA repair mechanisms in cancerFURGASON, John M; EL MUSTAPHA BAHASSI.Pharmacology & therapeutics (Oxford). 2013, Vol 137, Num 3, pp 298-308, issn 0163-7258, 11 p.Article

Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibitionKEDAR, Padmini S; STEFANICK, Donna F; HORTON, Julie K et al.DNA repair. 2008, Vol 7, Num 11, pp 1787-1798, issn 1568-7864, 12 p.Article

PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse developmentHUBER, Aline; BAI, Peter; MENISSIER DE MURCIA, Josiane et al.DNA repair. 2004, Vol 3, Num 8-9, pp 1103-1108, issn 1568-7864, 6 p.Article

PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignanciesLEE, J-M; LEDERMANN, J. A; KOHN, E. C et al.Annals of oncology. 2014, Vol 25, Num 1, pp 32-40, issn 0923-7534, 9 p.Article

Poly(ADP-ribosyl)ation affects stabilization of Che-1 protein in response to DNA damageGIULIA BACALINI, Maria; DI LONARDO, Debora; CAIAFA, Paola et al.DNA repair. 2011, Vol 10, Num 4, pp 380-389, issn 1568-7864, 10 p.Article

New perspectives in ovarian cancer treatmentSCHMID, Bernd C; OEHLER, Martin K.Maturitas (Amsterdam). 2014, Vol 77, Num 2, pp 128-136, issn 0378-5122, 9 p.Article

Olaparib chez les patientes mutées BRCA: Études de phase III SOLO 1 et 2GLADIEFF, Laurence; PUJADE-LAURAINE, Eric.Onko +. 2013, Vol 5, Num 42, pp 6-7, issn 2101-9495, 2 p., CAH2Article

Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cellsMANCHAO ZHANG; HONGPENG LIU; RIBO GUO et al.Biochemical pharmacology. 2003, Vol 66, Num 1, pp 93-103, issn 0006-2952, 11 p.Article

H2AX a Promising Biomarker for Lung Cancer: A ReviewMATTHAIOS, D; HOUNTIS, P; KARAKITSOS, P et al.Cancer investigation. 2013, Vol 31, Num 1-10, pp 582-599, issn 0735-7907, 18 p.Article

BRCA1- and BRCA2-related mutations: therapeutic implications in ovarian cancerPOTHURI, B.Annals of oncology. 2013, Vol 24, issn 0923-7534, viii22-viii27, SUP8Article

A PARP-I/JNK1 cascade participates in the synergistic apoptotic effect of TNFa and all-trans retinoic acid in APL cellsMATHIEU, J; FLEXOR, M; LANOTTE, M et al.Oncogene (Basingstoke). 2008, Vol 27, Num 24, pp 3361-3370, issn 0950-9232, 10 p.Article

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformationMEI YU; SCHREEK, Sabine; MEHRAEIN, Yasmin et al.Oncogene (Basingstoke). 2005, Vol 24, Num 12, pp 1982-1993, issn 0950-9232, 12 p.Article

PARP inhibition during alkylation-induced genotoxic stress signals a cell cycle checkpoint response mediated by ATMCARROZZA, Michael J; STEFANICK, Donna F; HORTON, Julie K et al.DNA repair. 2009, Vol 8, Num 11, pp 1264-1272, issn 1568-7864, 9 p.Article

Local DNA damage by proton microbeam irradiation induces poly(ADP-ribose) synthesis in mammalian cellsTARTIER, Laurence; SPENLEHAUER, Catherine; NEWMAN, Heidi C et al.Mutagenesis. 2003, Vol 18, Num 5, pp 411-416, issn 0267-8357, 6 p.Article

Development of a miniaturized assay for the high-throughput screening program for poly(ADP-ribose) polymerase-1LEE, S; KOO, H.-N; LEE, B. H et al.Methods and findings in experimental and clinical pharmacology. 2005, Vol 27, Num 9, pp 617-622, issn 0379-0355, 6 p.Article

EGFR-Activating Mutations Correlate with a Fanconi Anemia―like Cellular Phenotype That Includes PARP Inhibitor SensitivityPFÄFFLE, Heike N; MENG WANG; WILLERS, Henning et al.Cancer research (Chicago, Ill.). 2013, Vol 73, Num 20, pp 6254-6263, issn 0008-5472, 10 p.Article

Alkylation DNA damage in combination with PARP inhibition results in formation of S-phase-dependent double-strand breaksHEACOCK, Michelle L; STEFANICK, Donna F; HORTON, Julie K et al.DNA repair. 2010, Vol 9, Num 8, pp 929-936, issn 1568-7864, 8 p.Article

The PARP inhibitor ABT-888 synergizes irinotecan treatment of colon cancer cell linesDAVIDSON, David; YUNZHE WANG; ALOYZ, Raquel et al.Investigational new drugs. 2013, Vol 31, Num 2, pp 461-468, issn 0167-6997, 8 p.Article

5-AIQ inhibits H₂O₂-induced apoptosis through reactive oxygen species scavenging and Akt/GSK-3β signaling pathway in H9c2 cardiomyocytesPARK, Eun-Seok; JUN CHUL KANG; KANG, Do-Hyun et al.Toxicology and applied pharmacology. 2013, Vol 268, Num 1, pp 90-98, issn 0041-008X, 9 p.Article

TcPARP : A DNA damage-dependent poly(ADP-ribose) polymerase from Trypanosoma cruziFERNANDEZ VILLAMIL, Silvia H; BALTANAS, Rodrigo; ALONSO, Guillermo D et al.International journal for parasitology. 2008, Vol 38, Num 3-4, pp 277-287, issn 0020-7519, 11 p.Article

Neither energy collapse nor transcription underlie in vitro neurotoxicity of poly(ADP-ribose) polymerase hyper-activationFOSSATI, Silvia; CIPRIANI, Giulia; MORONI, Flavio et al.Neurochemistry international. 2007, Vol 50, Num 1, pp 203-210, issn 0197-0186, 8 p.Article

Efficacy of Chemotherapy in BRCA1/2 Mutation Carrier Ovarian Cancer in the Setting of PARP Inhibitor Resistance: A Multi-Institutional StudyJOO ERN ANG; GOURLEY, Charlie; BANERJEE, Susana et al.Clinical cancer research (Print). 2013, Vol 19, Num 19, pp 5485-5493, issn 1078-0432, 9 p.Article

Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancerZHU, Gui-Dong; JIANCHUN GONG; OLSON, Amanda M et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 15, pp 4635-4645, issn 0968-0896, 11 p.Article