The effect of food on the bioavailability and kinetics of the anticancer drug amsacrine and a new analogue, N-5-dimethyl-9-[(2-methoxy-4-methylsulphonylamino)phenylamino]-4 acridinecarboxamide in rabbitsPAXTON, J. W.Journal of pharmacy and pharmacology. 1986, Vol 38, Num 11, pp 837-840, issn 0022-3573Article

Absence of effect of propoxyphene on antipyrine kinetics in the rabbitPAXTON, J. W.Pharmacology. 1983, Vol 27, Num 4, pp 241-244, issn 0031-7012Article

Interaction of probenecid with the protein binding of methotrexatePAXTON, J. W.Pharmacology. 1984, Vol 28, Num 2, pp 86-89, issn 0031-7012Article

Elimination kinetics of amsacrine in the rabbit: evidence of nonlinearityPAXTON, J. W; JURLINA, J. L.Pharmacology. 1985, Vol 31, Num 1, pp 50-56, issn 0031-7012Article

Comparison of the blood-brain barrier and liver penetration of acridine antitumor drugsCORNFORD, E. M; YOUNG, D; PAXTON, J. W et al.Cancer chemotherapy and pharmacology. 1992, Vol 29, Num 6, pp 439-444, issn 0344-5704Article

Comparison of the pharmacokinetics and protein binding of the anticancer drug, amsacrine and a new analogue, N-5-dimethyl-9-[(2-methoxy-4-methylsulfonylamino)phenyl-amino]-4-acridinecarboxamide in rabbitsPAXTON, J. W; JURLINA, J. L.Cancer chemotherapy and pharmacology. 1986, Vol 16, Num 3, pp 253-256, issn 0344-5704Article

Propranolol disposition after acute myocardial infarctionPAXTON, J. W; NORRIS, R. M.Clinical pharmacology and therapeutics. 1984, Vol 36, Num 3, pp 337-342, issn 0009-9236Article

High-performance liquid chromatographic method for the determination of 4'-(9-acridinylamino)methanesulfon-m-anisidide in plasmaJURLINA, J. L; PAXTON, J. W.Journal of chromatography. 1983, Vol 276, Num 2, pp 367-374, issn 0021-9673Article

Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro: implications for prediction of metabolic interactions in vivoZHOU, S. F; TINGLE, M. D; KESTELL, P et al.Xenobiotica (London. Print). 2002, Vol 32, Num 2, pp 87-107, issn 0049-8254Article

Effects of phenytoin on cognitive-motor performance in children as a function of drug concentration, seizure type, and time of medicationAMAN, M. G; WERRY, J. S; PAXTON, J. W et al.Epilepsia (Copenhagen). 1994, Vol 35, Num 1, pp 172-180, issn 0013-9580Article

Pharmacokinetics of acridine-4-carboxamide in the rat, with extrapolation to humansPAXTON, J. W; YOUNG, D; ROBERTSON, I. G. C et al.Cancer chemotherapy and pharmacology. 1993, Vol 32, Num 4, pp 323-325, issn 0344-5704Article

Sustained release of a corticosteroid using polymeric implantsCAWLEY, S; ORMROD, D. J; PAXTON, J. W et al.Collection sécurité. 1986, Vol 19, Num 3-4, pp 233-243, issn 0538-4818Article

The effect of buthionine sulphoximine, cimetidine and phenobarbitone on the disposition of amsacrine in the rabbitPAXTON, J. W; FOOTE, S. E; SINGH, R. M et al.Cancer chemotherapy and pharmacology. 1986, Vol 18, Num 3, pp 208-212, issn 0344-5704Article

Pharmacokinetics of amsacrine in patients receiving combined chemotherapy for treatment of acute myelogenous leukemiaJURLINA, J. L; VARCOE, A. R; PAXTON, J. W et al.Cancer chemotherapy and pharmacology. 1985, Vol 14, Num 1, pp 21-25, issn 0344-5704Article

The xenobiotic transporter ABCG2 plays a novel role in differentiation of trophoblast-like BeWo cellsEVSEENKO, D. A; PAXTON, J. W; KEELAN, J. A et al.Placenta (Eastbourne). 2007, Vol 28, issn 0143-4004, S116-S120, SUPAConference Paper

Inter-species variation in the metabolism and inhibition of N-[(2'-dimethylamino)ethyl]acridine-4-carboxamide (DACA) by aldehyde oxidaseSCHOFIELD, P. C; ROBERTSON, I. G. C; PAXTON, J. W et al.Biochemical pharmacology. 2000, Vol 59, Num 2, pp 161-165, issn 0006-2952Article

Determination of two major metabolites of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid in hepatic microsomal incubations by high-performance liquid chromatography with fluorescence detectionSHUFENG ZHOU; PAXTON, J. W; TINGLE, M. D et al.Journal of chromatography. B, Biomedical sciences and applications. 1999, Vol 734, Num 1, pp 129-136, issn 1387-2273Article

Metabolism of the experimental antitumor agent acridine carboxamide in the mouseROBERTSON, I. G. C; PALMER, B. D; PAXTON, J. W et al.Drug metabolism and disposition. 1993, Vol 21, Num 3, pp 530-536, issn 0090-9556Article

Phase I trial of the amsacrine analogue 9-({2-methoxy-4-[(methylsulfonyl)amino]-phenyl}amino)-N,5-dimethyl-4-acridinecarboxamide (CI-921)HARDY, J. R; HARVEY, V. J; PAXTON, J. W et al.Cancer research (Baltimore). 1988, Vol 48, Num 22, pp 6593-6596, issn 0008-5472Article

Effect of sodium valproate on psychomotor performance in children as a function of dose, fluctuations in concentration, and diagnosisAMAN, M. G; WERRY, J. S; PAXTON, J. W et al.Epilepsia (Copenhagen). 1987, Vol 28, Num 2, pp 115-124, issn 0013-9580Article

Plasma and biliary disposition of pirenzepine in manLEE, S. P; PAXTON, J. W; CHOONG, Y. S et al.Clinical and experimental pharmacology and physiology. 1986, Vol 13, Num 3, pp 241-248, issn 0305-1870Article

The binding of amsacrine to human plasma proteinsPAXTON, J. W; JURLINA, J. L; FOOTE, S. E et al.Journal of pharmacy and pharmacology. 1986, Vol 38, Num 6, pp 432-438, issn 0022-3573Article

Pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (AS1404), a novel vascular disrupting agent, in phase I clinical trialJAMESON, M. B; BAGULEY, B. C; KESTELL, P et al.Cancer chemotherapy and pharmacology. 2007, Vol 59, Num 5, pp 681-687, issn 0344-5704, 7 p.Article

Blood-brain glucose transfer in the mouseCORNFORD, E. M; YOUNG, D; PAXTON, J. W et al.Neurochemical research. 1993, Vol 18, Num 5, pp 591-597, issn 0364-3190Article

Blood-brain barrier penetration of felbamateCORNFORD, E. M; YOUNG, D; PAXTON, J. W et al.Epilepsia (Copenhagen). 1992, Vol 33, Num 5, pp 944-954, issn 0013-9580Article