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Results 1 to 25 of 1160434

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Discovery and optimization of indole and 7-azaindoles as Rho kinase (ROCK) inhibitors (Part-II)HAMPTON SESSIONS, E; CHOWDHURY, Sarwat; BANNISTER, Thomas D et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 23, pp 7113-7118, issn 0960-894X, 6 p.Article

Discovery and optimization of indoles and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-I)CHOWDHURY, Sarwat; HAMPTON SESSIONS, E; BANNISTER, Thomas D et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 23, pp 7107-7112, issn 0960-894X, 6 p.Article

20-Aminosteroids as a novel class of selective and complete androgen receptor antagonists and inhibitors of prostate cancer cell growthFOUSTERIS, Manolis A; SCHUBERT, Undine; ROELL, Daniela et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 19, pp 6960-6969, issn 0968-0896, 10 p.Article

Mepolizumab and Eosinophil-Mediated DiseaseWALSH, G. M.Current medicinal chemistry. 2009, Vol 16, Num 36, pp 4774-4778, issn 0929-8673, 5 p.Article

Arylisothiocyanato selective androgen receptor modulators (SARMs) for prostate cancerDONG JIN HWANG; JUN YANG; HUIPING XU et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 19, pp 6525-6538, issn 0968-0896, 14 p.Article

Synthesis and biological profile of new 1,2,3,4-tetrahydroisoquinolines as selective carbonic anhydrase inhibitorsGITTO, Rosaria; DAMIANO, Francesca Maria; DE LUCA, Laura et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 23, pp 7003-7007, issn 0968-0896, 5 p.Article

Structure―activity relationships of bioisosteric replacement of the carboxylic acid in novel androgen receptor pure antagonistsYOSHINO, Hitoshi; SATO, Haruhiko; ARAI, Shinichi et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 9, pp 3159-3168, issn 0968-0896, 10 p.Article

The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentinZOIDIS, Grigoris; PAPANASTASIOU, Ioannis; DOTSIKAS, Ioannis et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 8, pp 2791-2798, issn 0968-0896, 8 p.Article

(Indol-3-yl)acétamides et analogues structuraux à activités antiallergique, immunomodulatrices et antitumorales = (Indol-3-yl)acetamides and structural analogues with potent antiallergy, immunomodulating and antineoplastic activitiesMenciu, Cécilia Cezarina; Le Baut, Guillaume.1997, 255 p.Thesis

Modulating Mesenchymal Stromal Cell Function with Cholesterol Synthesis Inhibitors : Targeting the Microenvironment in Hematological Malignancies: How to Condition both Stromal and Effector Cells to Overcome Cancer SpreadingPOGGI, A; ZOCCHI, M. R.Current medicinal chemistry. 2011, Vol 18, Num 34, pp 5196-5205, issn 0929-8673, 10 p.Article

Interactions des IPP avec le clopidogrel revisitées = PPI interactions with clopidogrel revisitedThe Medical letter on drugs and therapeutics (Edition française). 2009, Vol 31, Num 6, pp 21-22, issn 0253-8512, 2 p.Article

Metabolically labile cannabinoid esters : A 'soft drug' approach for the development of cannabinoid-based therapeutic drugsMINUTOLO, F; CASCIO, M. G; CARBONI, I et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 17, pp 4878-4881, issn 0960-894X, 4 p.Article

Rapid on-line profiling of estrogen receptor binding metabolites of tamoxifenKOOL, Jeroen; RAMAUTAR, Rawi; VAN LIEMPD, Sebastiaan M et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 11, pp 3287-3292, issn 0022-2623, 6 p.Article

Carbonic anhydrase inhibitors. Design of anticonvulsant sulfonamides incorporating indane moietiesCHAZALETTE, Celine; MASEREEL, Bernard; ROLIN, Stéphanie et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 23, pp 5781-5786, issn 0960-894X, 6 p.Article

A molecular basis of the therapeutic and psychoactive properties of cannabis (Δ9-tetrahydrocannabinol)NAHAS, Gabriel; HARVEY, David J; SUTIN, Kenneth et al.Progress in neuro-psychopharmacology & biological psychiatry. 2002, Vol 26, Num 4, pp 721-730, issn 0278-5846Conference Paper

Systematic review with meta-analysis: the effects of rifaximin in hepatic encephalopathyKIMER, N; KRAG, A; MØLLER, S et al.Alimentary pharmacology & therapeutics. 2014, Vol 40, Num 2, pp 123-132, issn 0269-2813, 10 p.Article

Intravenous acetylcysteine for indications other than acetaminophen overdoseBASS, Stephanie; ZOOK, Nathaniel.American journal of health-system pharmacy. 2013, Vol 70, Num 17, pp 1496-1501, issn 1079-2082, 6 p.Article

Assessing high affinity binding to HLA-DQ2.5 by a novel peptide library based approachJÜSE, Ulrike; ARNTZEN, Magnus; HØJRUP, Peter et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 7, pp 2470-2477, issn 0968-0896, 8 p.Article

(-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channelsORTAR, Giorgio; DE PETROCELLIS, Luciano; MORERA, Ludovica et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 9, pp 2729-2732, issn 0960-894X, 4 p.Article

Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitorsCUNY, Gregory D; ROBIN, Maxime; STEIN, Ross L et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 12, pp 3491-3494, issn 0960-894X, 4 p.Article

Towards biomarker-dependent individualized chemotherapy: Exploring cell-specific differences in oxaliplatin-DNA adduct distribution using accelerator mass spectrometrySANG SOO HAH; HENDERSON, Paul T; TURTELTAUB, Kenneth W et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 8, pp 2448-2451, issn 0960-894X, 4 p.Article

New 1α,25-Dihydroxy-19-norvitamin D3 Compounds Constrained in a Single A-Ring Conformation: Synthesis of the Analogues by Ring-Closing Metathesis Route and Their Biological EvaluationGLEBOCKA, Agnieszka; SOKOLOWSKA, Katarzyna; SICINSKI, Rafal R et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 11, pp 3496-3504, issn 0022-2623, 9 p.Article

Inhibition and Stimulation of Intestinal and Hepatic CYP3A Activity: Studies in Humanized CYP3A4 Transgenic Mice Using TriazolamVAN WATERSCHOOT, Robert A. B; ROOSWINKEL, Rogier W; SPARIDANS, Rolf W et al.Drug metabolism and disposition. 2009, Vol 37, Num 12, pp 2305-2313, issn 0090-9556, 9 p.Article

The dicationic derivatives of DBTAA : Interactions with DNA/RNA and antiproliferative effects on human cell linesMARIJANA RADIC STOJKOVIC; PIANTANIDA, Ivo; KRALJ, Marijeta et al.Bioorganic & medicinal chemistry. 2007, Vol 15, Num 4, pp 1795-1801, issn 0968-0896, 7 p.Article

Tumor necrosis factor-alpha monoclonal antibodies for Crohn's disease: Tipping the balanceDANESE, Silvio; PAGANO, Nico; ANGELUCCI, Erika et al.Current medicinal chemistry. 2007, Vol 14, Num 14, pp 1489-1497, issn 0929-8673, 9 p.Article

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