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Physiologically Based Pharmacokinetic (PBPK) Modeling in ChildrenBARRETT, J. S; DELLA CASA ALBERIGHI, O; LÄER, S et al.Clinical pharmacology and therapeutics. 2012, Vol 92, Num 1, pp 40-49, issn 0009-9236, 10 p.Article

Analysis of hepatic metabolism affecting pharmacokinetics of propranolol in humansKIRIYAMA, A; HONBO, A; IGA, K et al.International journal of pharmaceutics. 2008, Vol 349, Num 1-2, pp 53-60, issn 0378-5173, 8 p.Article

Estimation of interindividual variation in oxidative metabolism of dichloromethane in human volunteersSWEENEY, Lisa M; KIRMAN, Christopher R; MORGOTT, David A et al.Toxicology letters. 2004, Vol 154, Num 3, pp 201-216, issn 0378-4274, 16 p.Article

Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer model tests coupled with a physiologically based pharmacokinetic modelWAGNER, Christian; JANTRATID, Ekarat; KESISOGLOU, Filippos et al.European journal of pharmaceutics and biopharmaceutics. 2012, Vol 82, Num 1, pp 127-138, issn 0939-6411, 12 p.Article

Development and application of a generalized physiologically based pharmacokinetic model for multiple environmental contaminantsCAHILL, Thomas M; COUSINS, Ian; MACKAY, Donald et al.Environmental toxicology and chemistry. 2003, Vol 22, Num 1, pp 26-34, issn 0730-7268, 9 p.Article

Structural identifiability of physiologically based pharmacokinetic modelsYATES, James W. T.Journal of pharmacokinetics and pharmacodynamics (Print). 2006, Vol 33, Num 4, pp 421-439, issn 1567-567X, 19 p.Article

A physiological model for the estimation of the fraction dose absorbed in humansWILLMANN, Stefan; SCHMITT, Walter; KELDENICH, Jörg et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 16, pp 4022-4031, issn 0022-2623, 10 p.Article

Metabolic modeling: a tool of drug discovery in the post-genomic eraVOIT, Eberhard O.Drug discovery today. 2002, Vol 7, Num 11, pp 621-628, issn 1359-6446Article

Effects of the structure of a toxicokinetic model of butadiene inhalation exposure on computed production of carcinogenic intermediatesKOHN, M. C; MELNICK, R. L.Toxicology (Amsterdam). 1996, Vol 113, Num 1-3, pp 31-39, issn 0300-483XConference Paper

The Influence of Hepatic Transport on the Distribution Volumes and Mean Residence Time of Drug in the Body and the Accuracy of Estimating These Parameters by the Traditional Pharmacokinetic CalculationsBEREZHKOVSKIY, Leonid M.Journal of pharmaceutical sciences. 2011, Vol 100, Num 11, pp 5031-5047, issn 0022-3549, 17 p.Article

Maintaining steady state arterial alcohol levels in rats by using a physiologically based pharmacokinetic modelMORZORATI, Sandra L; RAMCHANDANI, Vijay A; LI, Ting-Kai et al.Alcohol (Fayetteville, NY). 2002, Vol 28, Num 3, pp 189-195, issn 0741-8329, 7 p.Article

A human physiological model describing acetone kinetics in blood and breath during various levels of physical exerciseMÖRK, Anna-Karin; JOHANSON, Gunnar.Toxicology letters. 2006, Vol 164, Num 1, pp 6-15, issn 0378-4274, 10 p.Article

Hydroquinone PBPK model refinement and application to dermal exposurePOET, Torka S; CARLTON, Betsy D; DEYO, James A et al.Food and chemical toxicology. 2010, Vol 48, Num 11, pp 3085-3092, issn 0278-6915, 8 p.Article

Intravenous Ethanol Infusions Can Mimic the Time Course of Breath Alcohol Concentrations Following Oral Alcohol Administration in Healthy VolunteersRAMCHANDANI, Vijay A; PLAWECKI, Martin; LI, Ting-Kai et al.Alcoholism, clinical and experimental research. 2009, Vol 33, Num 5, pp 938-944, issn 0145-6008, 7 p.Article

A Calibrated Human PBPK Model for Benzene Inhalation with Urinary Bladder and Bone Marrow CompartmentsKNUTSEN, Jeffrey S; KERGER, Brent D; FINLEY, Brent et al.Risk analysis. 2013, Vol 33, Num 7, pp 1237-1251, issn 0272-4332, 15 p.Article

PBPK Model Describes the Effects of Comedication and Genetic Polymorphism on Systemic Exposure of DrugsThat Undergo Multiple Clearance PathwaysVIEIRA, Md L. T; KIM, M.-J; APPARAJU, S et al.Clinical pharmacology and therapeutics. 2014, Vol 95, Num 5, pp 550-557, issn 0009-9236, 8 p.Article

Physiologically based pharmacokinetic modelling of human exposure to 2-butoxyethanolFRANKS, S. J; SPENDIFF, M. K; COCKER, J et al.Toxicology letters. 2006, Vol 162, Num 2-3, pp 164-173, issn 0378-4274, 10 p.Conference Paper

Physiologically based modeling of 1,2,4-trimethylbenzene inhalation toxicokineticsJÄRNBERG, J; JOHANSON, G.Toxicology and applied pharmacology. 1999, Vol 155, Num 3, pp 203-214, issn 0041-008XArticle

Reducing whole body physiologically based pharmacokinetic models using global sensitivity analysis : diazepam case studyGUEORGUIEVA, Ivelina; NESTOROV, Ivan A; ROWLAND, Malcolm et al.Journal of pharmacokinetics and pharmacodynamics (Print). 2006, Vol 33, Num 1, pp 1-27, issn 1567-567X, 27 p.Article

Fuzzy simulation of pharmacokinetic models: Case study of whole body physiologically based model of diazepamGUEORGUIEVA, Ivelina I; NESTOROV, Ivan A; ROWLAND, Malcolm et al.Journal of pharmacokinetics and pharmacodynamics (Print). 2004, Vol 31, Num 3, pp 185-213, issn 1567-567X, 29 p.Article

On the incorporation of chemical-specific information in risk assessmentCLEWELL, Harvey J; ANDERSEN, Melvin E; BLAAUBOER, Bas J et al.Toxicology letters. 2008, Vol 180, Num 2, pp 100-109, issn 0378-4274, 10 p.Article

Development and evaluation of a generic physiologically based pharmacokinetic model for childrenEDGINTON, Andrea N; SCHMITT, Walter; WILLMANN, Stefan et al.Clinical pharmacokinetics. 2006, Vol 45, Num 10, pp 1013-1034, issn 0312-5963, 22 p.Article

A physiologically based biokinetic model for cesium in the human bodyLEGGETT, R. W; WILLIAMS, L. R; MELO, D. R et al.Science of the total environment. 2003, Vol 317, Num 1-3, pp 235-255, issn 0048-9697, 21 p.Article

A comparison of 1H8- and 2H8-toluene toxicokinetics in menPIERCE, C. H; LEWANDOWSKI, T. A; DILLS, R. L et al.Xenobiotica (London. Print). 1999, Vol 29, Num 1, pp 93-108, issn 0049-8254Article

Structural identifiability of PBPK models : Practical consequences for modeling strategies and study designsSLOB, W; JANSSEN, P. H. M; VAN DEN HOF, J. M et al.Critical reviews in toxicology. 1997, Vol 27, Num 3, pp 261-272, issn 1040-8444Article

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