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Modular theranostic prodrug based on a FRET-activated self-immolative linerREDY, Orit; SHABAT, Doron.Journal of controlled release. 2012, Vol 164, Num 3, pp 276-282, issn 0168-3659, 7 p.Article

Recent Trends in Targeted Anticancer Prodrug and Conjugate DesignSINGH, Yashveer; PALOMBO, Matthew; SINKO, Patrick J et al.Current medicinal chemistry. 2008, Vol 15, Num 18, pp 1802-1826, issn 0929-8673, 25 p.Article

Predictive Physiologically Based Pharmacokinetic Model for Antibody-Directed Enzyme Prodrug TherapyLANYAN FANG; DUXIN SUN.Drug metabolism and disposition. 2008, Vol 36, Num 6, pp 1153-1165, issn 0090-9556, 13 p.Article

β-Aminoketones as prodrugs with pH-controlled activationLUISA SIMPLICIO, Ana; CLANCY, John M; GILMER, John F et al.International journal of pharmaceutics. 2007, Vol 336, Num 2, pp 208-214, issn 0378-5173, 7 p.Article

Evaluating Aziridinyl Nitrobenzamide Compounds as Leishmanicidal ProdrugsVOAK, Andrew A; SEIFERT, Karin; HELSBY, Nuala A et al.Antimicrobial agents and chemotherapy. 2014, Vol 58, Num 1, pp 370-377, issn 0066-4804, 8 p.Article

Prodrugs for Targeted Tumor Therapies: Recent Developments in ADEPT, GDEPT and PMTTIETZE, Lutz F; SCHMUCK, Kianga.Current pharmaceutical design (Print). 2011, Vol 17, Num 32, pp 3527-3547, issn 1381-6128, 21 p.Article

Strategies in the design of solution-stable, water-soluble prodrugs. I: A physical-organic approach to pro-moiety selection for 21-esters of corticosteroidsANDERSON CONRADI, R. A; KNUTH, K. E.Journal of pharmaceutical sciences. 1985, Vol 74, Num 4, pp 365-374, issn 0022-3549Article

Strategies in the design of solution-stable, water-soluble prodrugs. II: Properties of micellar prodrugs of methyl-prednisoloneANDERSON, B. D; CONRADI, R. A; KNUTH, K. E et al.Journal of pharmaceutical sciences. 1985, Vol 74, Num 4, pp 375-381, issn 0022-3549Article

Strategies in the design of solution-stable, water-soluble prodrugs. III: Influence of the pro-moiety on the bioconversion of 21-esters of corticosteroidsANDERSON, B. D; CONRADI, R. A; SPILMAN, C. H et al.Journal of pharmaceutical sciences. 1985, Vol 74, Num 4, pp 382-387, issn 0022-3549Article

ETUDE COMPARATIVE DU DIAZEPAM ET DE DERIVES ANALOGUES SUBSTITUES EN 1 PAR DES GROUPES ORGANOMETALLIQUESPITET G; SATGE J; CASTEL A et al.1978; ANN. PHARM. FR.; FRA; DA. 1978; VOL. 36; NO 11-12; PP. 621-624; ABS. ENG; BIBL. 16 REF.Article

Prodrugs: Some Thoughts and Current IssuesSTELLA, Valentino J.Journal of pharmaceutical sciences. 2010, Vol 99, Num 12, pp 4755-4765, issn 0022-3549, 11 p.Article

Codrug: An efficient approach for drug optimizationDAS, N; DHANAWAT, M; DASH, B et al.European journal of pharmaceutical sciences. 2010, Vol 41, Num 5, pp 571-588, issn 0928-0987, 18 p.Article

The antineoplastic efficacy of the prodrug Cloretazine is produced by the synergistic interaction of carbamoylating and alkylating products of its activationBAUMANN, Raymond P; SEOW, Helen A; SHYAM, Krishnamurthy et al.Oncology research. 2005, Vol 15, Num 6, pp 313-325, issn 0965-0407, 13 p.Article

2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPTHELSBY, N. A; FERRY, D. M; PATTERSON, A. V et al.British journal of cancer. 2004, Vol 90, Num 5, pp 1084-1092, issn 0007-0920, 9 p.Article

Synthesis and biological evaluation of selective and potent cyclin-dependent kinase inhibitorsN'GOMPAZA-DIARRA, Joannah; BETTAYEB, Karima; GRESH, Nohad et al.European journal of medicinal chemistry. 2012, Vol 56, pp 210-216, issn 0223-5234, 7 p.Article

Metabolism of 3-(chlorophenyl)pyrrolidine. Structural effects in conversion of a prototype γ-aminobutyric acid prodrug to lactam and γ-aminobutyric acid type metabolitesWALL, G. M; BAKER, J. K.Journal of medicinal chemistry (Print). 1989, Vol 32, Num 6, pp 1340-1348, issn 0022-2623, 9 p.Article

Prodrugs of 6-thiopurines: enhanced delivery through the skinSLOAN, K. B; HASHIDA, M; ALEXANDER, J et al.Journal of pharmaceutical sciences. 1983, Vol 72, Num 4, pp 372-378, issn 0022-3549Article

Synthesis and biological evaluation of ester prodrugs of benzafibrate as orally active hypolipidemic agentsBANDGAR, Babasaheb P; SARANGDHAR, Rajendra J; FRUTHOUS, Khan et al.European journal of medicinal chemistry. 2012, Vol 57, pp 217-224, issn 0223-5234, 8 p.Article

Prodrugs as drug delivery systems. XXVI: Preparation and enzymatic hydrolysis of various water-soluble amino acid esters of metronidazoleBUNDGAARD, H; LARSEN, C; THORBEK, P et al.International journal of pharmaceutics. 1984, Vol 18, Num 1-2, pp 67-77, issn 0378-5173Article

N,N'-Dialkylaminoalkylcarbonyl (DAAC) prodrugs and aminoalkylcarbonyl (AAC) prodrugs of 4-hydroxyacetanilide and naltrexone with improved skin permeation propertiesDEVARAJAN-KETHA, H; SLOAN, K. B.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 13, pp 4078-4082, issn 0960-894X, 5 p.Article

Cytosolic β-glycosidases for activation of glycoside prodrugs of daunorubicinDE GRAAF, Michelle; PINEDO, Herbert M; QUADIR, Razi et al.Biochemical pharmacology. 2003, Vol 65, Num 11, pp 1875-1881, issn 0006-2952, 7 p.Article

Phosphorus GABA analogues as potential prodrugsCATES, L. A; RASHED, M. S.Pharmaceutical research. 1984, Num 6, pp 271-274, issn 0724-8741Article

Prodrugs as drug delivery systems. XXVIII: Structural factors influencing the rate of hydrolysis of oxazolidines ― a potential prodrug typeBUUR, A; BUNDGAARD, H.International journal of pharmaceutics. 1984, Vol 18, Num 3, pp 325-334, issn 0378-5173Article

Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moietyTICHY, Tomas; ANDREI, Graciela; SNOECK, Robert et al.European journal of medicinal chemistry. 2012, Vol 55, pp 307-314, issn 0223-5234, 8 p.Article

Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4'-phosphonobut-2'-en-1'-yl]purine nucleosidesPRADERE, Ugo; ROY, Vincent; MONTAGU, Aurélien et al.European journal of medicinal chemistry. 2012, Vol 57, pp 126-133, issn 0223-5234, 8 p.Article

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