Synthesis and biological evaluation of ester prodrugs of benzafibrate as orally active hypolipidemic agentsBANDGAR, Babasaheb P; SARANGDHAR, Rajendra J; FRUTHOUS, Khan et al.European journal of medicinal chemistry. 2012, Vol 57, pp 217-224, issn 0223-5234, 8 p.Article

Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4'-phosphonobut-2'-en-1'-yl]purine nucleosidesPRADERE, Ugo; ROY, Vincent; MONTAGU, Aurélien et al.European journal of medicinal chemistry. 2012, Vol 57, pp 126-133, issn 0223-5234, 8 p.Article

Synthesis and evaluation of mutual prodrugs of ibuprofen with menthol, thymol and eugenolREDASANI, Vivekkumar K; BARI, Sanjay B.European journal of medicinal chemistry. 2012, Vol 56, pp 134-138, issn 0223-5234, 5 p.Article

Synthesis, chemical and enzymatic hydrolysis, and aqueous solubility of amino acid ester prodrugs of 3-carboranyl thymidine analogs for boron neutron capture therapy of brain tumorsHASABELNABY, Sherifa; GOUDAH, Ayman; AGARWAL, Hitesh K et al.European journal of medicinal chemistry. 2012, Vol 55, pp 325-334, issn 0223-5234, 10 p.Article

β-Aminoketones as prodrugs with pH-controlled activationLUISA SIMPLICIO, Ana; CLANCY, John M; GILMER, John F et al.International journal of pharmaceutics. 2007, Vol 336, Num 2, pp 208-214, issn 0378-5173, 7 p.Article

N,N'-Dialkylaminoalkylcarbonyl (DAAC) prodrugs and aminoalkylcarbonyl (AAC) prodrugs of 4-hydroxyacetanilide and naltrexone with improved skin permeation propertiesDEVARAJAN-KETHA, H; SLOAN, K. B.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 13, pp 4078-4082, issn 0960-894X, 5 p.Article

Prodrugs: Some Thoughts and Current IssuesSTELLA, Valentino J.Journal of pharmaceutical sciences. 2010, Vol 99, Num 12, pp 4755-4765, issn 0022-3549, 11 p.Article

Modular theranostic prodrug based on a FRET-activated self-immolative linerREDY, Orit; SHABAT, Doron.Journal of controlled release. 2012, Vol 164, Num 3, pp 276-282, issn 0168-3659, 7 p.Article

The antineoplastic efficacy of the prodrug Cloretazine is produced by the synergistic interaction of carbamoylating and alkylating products of its activationBAUMANN, Raymond P; SEOW, Helen A; SHYAM, Krishnamurthy et al.Oncology research. 2005, Vol 15, Num 6, pp 313-325, issn 0965-0407, 13 p.Article

2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPTHELSBY, N. A; FERRY, D. M; PATTERSON, A. V et al.British journal of cancer. 2004, Vol 90, Num 5, pp 1084-1092, issn 0007-0920, 9 p.Article

Prodrugs for Targeted Tumor Therapies: Recent Developments in ADEPT, GDEPT and PMTTIETZE, Lutz F; SCHMUCK, Kianga.Current pharmaceutical design (Print). 2011, Vol 17, Num 32, pp 3527-3547, issn 1381-6128, 21 p.Article

Evaluating Aziridinyl Nitrobenzamide Compounds as Leishmanicidal ProdrugsVOAK, Andrew A; SEIFERT, Karin; HELSBY, Nuala A et al.Antimicrobial agents and chemotherapy. 2014, Vol 58, Num 1, pp 370-377, issn 0066-4804, 8 p.Article

Strategies in the design of solution-stable, water-soluble prodrugs. I: A physical-organic approach to pro-moiety selection for 21-esters of corticosteroidsANDERSON CONRADI, R. A; KNUTH, K. E.Journal of pharmaceutical sciences. 1985, Vol 74, Num 4, pp 365-374, issn 0022-3549Article

Strategies in the design of solution-stable, water-soluble prodrugs. II: Properties of micellar prodrugs of methyl-prednisoloneANDERSON, B. D; CONRADI, R. A; KNUTH, K. E et al.Journal of pharmaceutical sciences. 1985, Vol 74, Num 4, pp 375-381, issn 0022-3549Article

Strategies in the design of solution-stable, water-soluble prodrugs. III: Influence of the pro-moiety on the bioconversion of 21-esters of corticosteroidsANDERSON, B. D; CONRADI, R. A; SPILMAN, C. H et al.Journal of pharmaceutical sciences. 1985, Vol 74, Num 4, pp 382-387, issn 0022-3549Article

Synthesis of monosaccharide derivatives and polymeric prodrugs of 5-fluorouridine via two-step enzymatic or chemo-enzymatic highly regioselective strategyQI WU; AIHUA XIA; XIANFU LIN et al.Journal of molecular catalysis. B, Enzymatic. 2008, Vol 54, Num 3-4, pp 76-82, issn 1381-1177, 7 p.Article

Stimuli-responsive antioxidant nanoprodrugs of NSAIDsLEE, Bong-Seop; XIANGPENG YUAN; QIJIN XU et al.International journal of pharmaceutics (Print). 2009, Vol 372, Num 1-2, pp 112-124, issn 0378-5173, 13 p.Article

The rationality for using prodrug approach in drug discovery programs for new xenobiotics: opportunities and challengesSRINIVAS, Nuggehally R.European journal of drug metabolism and pharmacokinetics. 2011, Vol 36, Num 2, pp 49-59, issn 0378-7966, 11 p.Article

Metabolism of 3-(chlorophenyl)pyrrolidine. Structural effects in conversion of a prototype γ-aminobutyric acid prodrug to lactam and γ-aminobutyric acid type metabolitesWALL, G. M; BAKER, J. K.Journal of medicinal chemistry (Print). 1989, Vol 32, Num 6, pp 1340-1348, issn 0022-2623, 9 p.Article

Prodrugs as drug delivery systems. XXVI: Preparation and enzymatic hydrolysis of various water-soluble amino acid esters of metronidazoleBUNDGAARD, H; LARSEN, C; THORBEK, P et al.International journal of pharmaceutics. 1984, Vol 18, Num 1-2, pp 67-77, issn 0378-5173Article

Intestinal permeability of lamivudine (3TC) and two novel 3TC prodrugs. Experimental and theoretical analysesGUALDESI, María S; BRINON, Margarita C; QUEVEDO, Mario A et al.European journal of pharmaceutical sciences. 2012, Vol 47, Num 5, pp 965-978, issn 0928-0987, 14 p.Article

Amplified release through the stimulus triggered degradation of self-immolative oligomers, dendrimers, and linear polymersWONG, Andrew D; DEWIT, Matthew A; GILLIES, Elizabeth R et al.Advanced drug delivery reviews. 2012, Vol 64, Num 11, pp 1031-1045, issn 0169-409X, 15 p.Article

Linear Synthesis of Chiral cyc/oSal-PronucleotidesRIOS MORALES, Edwuin Hander; ROMAN, Cristina Arbelo; THOMANN, Jens Oliver et al.European journal of organic chemistry (Print). 2011, Num 23, pp 4397-4408, issn 1434-193X, 12 p.Article

Squalenoyl Gemcitabine Monophosphate: Synthesis, Characterisation of Nanoassemblies and Biological EvaluationCARON, Joachim; LEPELTIER, Elise; HARIVARDHAN REDDY, L et al.European journal of organic chemistry (Print). 2011, Num 14, pp 2615-2628, issn 1434-193X, 14 p.Article

New prodrugs of Adefovir and CidofovirTICHY, Tomáš; ANDREI, Graciela; DRACINSKY, Martin et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 11, pp 3527-3539, issn 0968-0896, 13 p.Article