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kw.\*:("Quinoléine-3-carbonitrile dérivé")

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The chemistry of multi-protic drugs Part 1: A potentiometric, multi-wavelength UV and NMR pH titrimetric study of the micro-speciation of SKI-606BOX, Karl J; DONKOR, Rachel E; JUPP, Philip. A et al.Journal of pharmaceutical and biomedical analysis. 2008, Vol 47, Num 2, pp 303-311, issn 0731-7085, 9 p.Article

Discovering some novel tetrahydroquinoline derivatives bearing the biologically active sulfonamide moiety as a new class of antitumor agentsALQASOUMI, Saleh I; AL-TAWEEL, Areej M; ALAFEEFY, Ahmed M et al.European journal of medicinal chemistry. 2010, Vol 45, Num 5, pp 1849-1853, issn 0223-5234, 5 p.Article

Synthesis of 7-(E)-alkenyl-4-amino-3-quinolinecarbonitriles via Pd-mediated Heck, Stille, and Suzuki reactionsWANG, Yanong D; DUTIA, Minu; BRAWNER FLOYD, M et al.Tetrahedron (Oxford. Print). 2009, Vol 65, Num 1, issn 0040-4020, 2, 57-61 [6 p.]Article

Inhibition of Src kinase activity by 7-ethynyl-4-phenylamino-3-quinolinecarbonitriles : Identification of SKS-927BOSCHELLI, Diane H; BARRIOS SOSA, Ana Carolina; GOLAS, Jennifer M et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 5, pp 1358-1361, issn 0960-894X, 4 p.Article

C-C bond formation at C-2 of a quinoline ring: Synthesis of 2-(1H-indol-3-yl) quinoline-3-carbonitrile derivatives as a new class of PDE4 inhibitorsSHIVA KUMAR, K; KIRAN KUMAR, S; PAL, Manojit et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 7, pp 2199-2207, issn 0968-0896, 9 p.Article

Novel Patented Src Kinase InhibitorLU, Xiao-Ling; LIU, Xiao-Yu; XIN CAO et al.Current medicinal chemistry. 2012, Vol 19, Num 12, pp 1821-1829, issn 0929-8673, 9 p.Article

Further studies on ethenyl and ethynyl-4-phenylamino-3-quinolinecarbonitriles : identification of a subnanomolar Src kinase inhibitorSOSA, Ana Carolina; BOSCHELLI, Diane H; BIQI WU et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 6, pp 1743-1747, issn 0960-894X, 5 p.Article

Development of a new epidermal growth factor receptor positron emission tomography imaging agent based on the 3-cyanoquinoline core: Synthesis and biological evaluationPISANESCHI, Federica; NGUYEN, Quang-De; SHAMSAEI, Elham et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 18, pp 6634-6645, issn 0968-0896, 12 p.Article

Design, synthesis and anticancer evaluation of novel tetrahydroquinoline derivatives containing sulfonamide moietyGHORAB, Mostafa M; RAGAB, Fatma A; HAMED, Mostafa M et al.European journal of medicinal chemistry. 2009, Vol 44, Num 10, pp 4211-4217, issn 0223-5234, 7 p.Article

Binding modes of 6,7 di-substituted 4-anilinoquinoline-3-carbonitriles to EGFRAKULA, Nagaraju; BHALLA, Jag; SRIDHAR, Jayalakshmi et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 13, pp 3397-3400, issn 0960-894X, 4 p.Article

Synthesis and src kinase inhibitory activity of a series of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-furyl-3-quinolinecarbonitrilesBOSCHELLI, Diane H; BIQI WU; FEI YE et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 26, pp 7868-7876, issn 0022-2623, 9 p.Article

Selective inhibitors of tumor progression loci-2 (Tp12) kinase with potent inhibition of TNF-α production in human whole bloodJUNJUN WU; GREEN, Neal; TAM, Steve Y et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 13, pp 3485-3488, issn 0960-894X, 4 p.Article

PDE-10A inhibitors as insulin secretagoguesCANTIN, Louis-David; MAGNUSON, Steven; GORE-WILLSE, Ann et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 10, pp 2869-2873, issn 0960-894X, 5 p.Article

7-(Aryl/heteroaryl-2-ylethynyl)-4-phenylamino-3- quinolinecarbonitriles as new Src kinase inhibitors : Addition of water solubilizing groupsBIQI WU; SOSA, Ana Carolina Barrios; BOSCHELLI, Diane H et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 15, pp 3993-3997, issn 0960-894X, 5 p.Article

Inhibition of Tpl2 kinase and TNFα production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritisYONGHAN HU; GREEN, Neal; NICKERSON-NUTTER, Cheryl et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 23, pp 6067-6072, issn 0960-894X, 6 p.Article

Structural insights into the ATP binding pocket of the anaplastic lymphoma kinase by site-directed mutagenesis, inhibitor binding analysis, and homology modelingGUNBY, Rosalind H; AHMED, Shaheen; SOTTOCORNOLA, Roberta et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 19, pp 5759-5768, issn 0022-2623, 10 p.Article

3D-QSAR studies on c-Src kinase inhibitors and docking analyses of a potent dual kinase inhibitor of c-Src and c-Abl kinasesTHAIMATTAM, Ram; DAGA, Pankaj R; BANERJEE, Rahul et al.Bioorganic & medicinal chemistry. 2005, Vol 13, Num 15, pp 4704-4712, issn 0968-0896, 9 p.Article

Synthesis and structure-activity relationships of 6,7-disubstituted 4-anilinoquinoline-3-carbonitriles. The design of an orally active, irreversible inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor-2 (HER-2)WISSNER, Allan; OVERBEEK, Elsebe; RABINDRAN, Sridhar K et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 1, pp 49-63, issn 0022-2623, 15 p.Article

A Targeted Therapy for Protein and Lipid Kinases in Chronic Lymphocytic LeukemiaROBAK, P; ROBAK, T.Current medicinal chemistry. 2012, Vol 19, Num 31, pp 5294-5318, issn 0929-8673, 25 p.Article

Design and synthesis of 7-alkoxy-4-heteroarylamino-3-quinolinecarbonitriles as dual inhibitors of c-Src kinase and nitric oxide synthaseXIN CAO; YOU, Qi-Dong; LI, Zhi-Yu et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 11, pp 5890-5898, issn 0968-0896, 9 p.Article

Redesigning Kinase Inhibitors to Enhance SpecificityCRESPO, Alejandro; XI ZHANG; FERNANDEZ, Ariel et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 16, pp 4890-4898, issn 0022-2623, 9 p.Article

Optimization of 6,7-disubstituted-4-(arylamino)quinoline-3-carbonitriles as orally active, irreversible inhibitors of human epidermal growth factor receptor-2 kinase activityTSOU, Hwei-Ru; OVERBEEK-KLUMPERS, Elsebe G; RABINDRAN, Sridhar K et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 4, pp 1107-1131, issn 0022-2623, 25 p.Article

Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 2. Antiproliferative and Antitubulin Activities of Pyrano[3,2-c]pyridones and Pyrano[3,2-c]quinolonesMAGEDOV, Igor V; MANPADI, Madhuri; KNEE, Erica J et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 8, pp 2561-2570, issn 0022-2623, 10 p.Article

Synthesis of new fluorescent dyes from 6-methoxy-1-chloro-3,4-dihydronaphthalene-2-carboxaldehydeRAJAGOPAL, R; SESHADRI, S.Dyes and pigments. 1991, Vol 17, Num 1, pp 57-69, issn 0143-7208Article

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