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Results 1 to 16 of 16

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Therapeutic protein aggregation: mechanisms, design, and controlROBERTS, Christopher J.Trends in biotechnology (Regular ed.). 2014, Vol 32, Num 7, pp 372-380, issn 0167-7799, 9 p.Article

Coarse-Grained Modeling of Protein Second Osmotic Virial Coefficients: Sterics and Short-Ranged AttractionsGRÜNBERGER, Alexander; LAI, Pin-Kuang; BLANCO, Marco A et al.The Journal of physical chemistry. B. 2013, Vol 117, Num 3, pp 763-770, issn 1520-6106, 8 p.Article

Predicting solution aggregation rates for therapeutic proteins: Approaches and challengesROBERTS, Christopher J; DAS, Tapan K; SAHIN, Erinc et al.International journal of pharmaceutics (Print). 2011, Vol 418, Num 2, pp 318-333, issn 0378-5173, 16 p.Article

Protein aggregation, particle formation, characterization & rheologyAMIN, Samiul; BARNETT, Gregory V; PATHAK, Jai A et al.Current opinion in colloid & interface science. 2014, Vol 19, Num 5, pp 438-449, issn 1359-0294, 12 p.Article

Folding and aggregation of a multi-domain engineered immunotoxinMAURER, Ronald W; HUNTER, Alan K; XIANGYANG WANG et al.Biochemical engineering journal. 2013, Vol 81, pp 8-14, issn 1369-703X, 7 p.Article

Engineering pharmaceutical stability with amorphous solidsROBERTS, Christopher J; DEBENEDETTI, Pablo G.AIChE journal. 2002, Vol 48, Num 6, pp 1140-1144, issn 0001-1541Article

Functional profiling of the Saccharomyces cerevisiae genomeGLAEVER, Guri; CHU, Angela M; ARKIN, Adam P et al.Nature (London). 2002, Vol 418, Num 6896, pp 387-391, issn 0028-0836Article

Modulation of Self-Association and Subsequent Fibril Formation in an Alanine-Rich Helical PolypeptideTOP, Ayben; KIICK, Kristi L; ROBERTS, Christopher J et al.Biomacromolecules. 2008, Vol 9, Num 6, pp 1595-1603, issn 1525-7797, 9 p.Article

Characterization of High-Molecular-Weight Nonnative Aggregates and Aggregation Kinetics by Size Exclusion Chromatography With Inline Multi-Angle Laser Light ScatteringYI LI; WEISS, William F; ROBERTS, Christopher J et al.Journal of pharmaceutical sciences. 2009, Vol 98, Num 11, pp 3997-4016, issn 0022-3549, 20 p.Article

Coarse-Grained Model for Colloidal Protein Interactions, B22, and Protein Cluster FormationBLANCO, Marco A; SAHIN, Erinc; ROBINSON, Anne S et al.The Journal of physical chemistry. B. 2013, Vol 117, Num 50, pp 16013-16028, issn 1520-6106, 16 p.Article

Aggregation and pH-Temperature Phase Behavior for Aggregates of an IgG2 AntibodySAHIN, Erinc; WEISS IV, William F; KROETSCH, Andrew M et al.Journal of pharmaceutical sciences. 2012, Vol 101, Num 5, pp 1678-1687, issn 0022-3549, 10 p.Article

Relating Particle Formation to Salt- and pH-Dependent Phase Separation of Non-Native Aggregates of Alpha-Chymotrypsinogen AKROETSCH, Andrew M; SAHIN, Erinc; WANG, Hsiang-Yun et al.Journal of pharmaceutical sciences. 2012, Vol 101, Num 10, pp 3651-3660, issn 0022-3549, 10 p.Article

Irreversible aggregation of recombinant bovine granulocyte-colony stimulating Factor (bG-CSF) and implications for predicting protein shelf lifeROBERTS, Christopher J; DARRINGTON, Richard T; WHITLEY, Maureen B et al.Journal of pharmaceutical sciences. 2003, Vol 92, Num 5, pp 1095-1111, issn 0022-3549, 17 p.Article

Nonnative Aggregation of an IgG1 Antibody in Acidic Conditions, Part 2: Nucleation and Growth Kinetics with Competing Growth MechanismsBRUMMITT, Rebecca K; NESTA, Douglas P; LIUQUAN CHANG et al.Journal of pharmaceutical sciences. 2011, Vol 100, Num 6, pp 2104-2119, issn 0022-3549, 16 p.Article

Principles, Approaches, and Challenges for Predicting Protein Aggregation Rates and Shelf LifeWEISS, William F; YOUNG, Teresa M; ROBERTS, Christopher J et al.Journal of pharmaceutical sciences. 2009, Vol 98, Num 4, pp 1246-1277, issn 0022-3549, 32 p.Article

Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemiaPEK YEE LUM; HE, Yudong D; ADAMSON, Gary E et al.Genomics (San Diego, Calif.). 2007, Vol 90, Num 4, pp 464-473, issn 0888-7543, 10 p.Article

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