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Results 1 to 25 of 86

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St. John's wort and its constituent hyperforin concordantly regulate expression of genes encoding enzymes involved in basic cellular pathwaysKRUSEKOPF, Solveigh; ROOTS, Ivar.Pharmacogenetics and genomics (Print). 2005, Vol 15, Num 11, pp 817-829, issn 1744-6872, 13 p.Article

Vitamin D receptor poly(A) microsatellite and colorectal cancer risk in CaucasiansFLIIGGE, Jana; LASCHINSKI, Gabriele; ROOTS, Ivar et al.International journal of colorectal disease (Print). 2009, Vol 24, Num 2, pp 171-175, issn 0179-1958, 5 p.Article

CYP1A1 genotype-selective inhibition of benzo[a]pyrene activation by quercetinSCHWARZ, Dieter; KISSELEV, Pyotr; ROOTS, Ivar et al.European journal of cancer (1990). 2005, Vol 41, Num 1, pp 151-158, issn 0959-8049, 8 p.Article

Association of nat1 and NAT2 polymorphisms to urinary bladder cancer: significantly reduced risk in subjects with nat1*10CASCORBI, Ingolf; ROOTS, Ivar; BROCKMÖLLER, Jürgen et al.Cancer research (Baltimore). 2001, Vol 61, Num 13, pp 5051-5056, issn 0008-5472Article

Pharmacogenetics of the human drug-transporter gene MDR1 : impact of polymorphisms on pharmacotherapyBRINKMANN, Ulrich; ROOTS, Ivar; EICHELBAUM, Michel et al.Drug discovery today. 2001, Vol 6, Num 16, pp 835-839, issn 1359-6446Article

Benzydamine N-oxidation as an index reaction reflecting FMO activity in human liver microsomes and impact of fm03 polymorphisms on enzyme activitySTÖRMER, Elke; ROOTS, Ivar; BROCKMÖLLER, Jürgen et al.British journal of clinical pharmacology. 2000, Vol 50, Num 6, pp 553-561, issn 0306-5251Article

A single nucleotide polymorphism in the human H-ras proto-oncogene determines the risk of urinary bladder cancerJOHNE, Andreas; ROOTS, Ivar; BROCKMÖLLER, Jürgen et al.Cancer epidemiology, biomarkers & prevention. 2003, Vol 12, Num 1, pp 68-70, issn 1055-9965, 3 p.Article

Differential drug-induced mRNA expression of human CYP3A4 compared to CYP3A5, CYP3A7 and CYP3A43KRUSEKOPF, Solveigh; ROOTS, Ivar; KLEEBERG, Ullrich et al.European journal of pharmacology. 2003, Vol 466, Num 1-2, pp 7-12, issn 0014-2999, 6 p.Article

In-vitro transport characteristics discriminate wild-type ABCB1 (MDR1) from ALA893SER and ALA893THR polymorphismsSCHAEFER, Melanie; ROOTS, Ivar; GERLOFF, Thomas et al.Pharmacogenetics and genomics (Print). 2006, Vol 16, Num 12, pp 855-861, issn 1744-6872, 7 p.Article

St. John's wort extracts and some of their constituents potently inhibit ultimate carcinogen formation from benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1SCHWARZ, Dieter; KISSELEV, Pyotr; ROOTS, Ivar et al.Cancer research (Baltimore). 2003, Vol 63, Num 22, pp 8062-8068, issn 0008-5472, 7 p.Article

Quantitative determination of the human MRP1 and MRP2 mRNA expression in FACS-sorted peripheral blood CD4+, CD8+, CD19+, and CD56+ cellsOSELIN, Kersti; MROZIKIEWICZ, Przemyslaw M; PÄHKLA, Rein et al.European journal of haematology. 2003, Vol 71, Num 2, pp 119-123, issn 0902-4441, 5 p.Article

Trimipramine pharmacokinetics after intravenous and oral administration in carriers of CYP2D6 genotypes predicting poor, extensive and ultrahigh activityKIRCHHEINER, Julia; SASSE, Johanna; MEINEKE, Ingolf et al.Pharmacogenetics (London). 2003, Vol 13, Num 12, pp 721-728, issn 0960-314X, 8 p.Article

Rapid quantification of CYP3A4 expression in human leukocytes by real-time reverse transcription-PCRNOWAKOWSKI-GASHAW, Isabella; MROZIKIEWICZ, Przemyslaw M; ROOTS, Ivar et al.Clinical chemistry (Baltimore, Md.). 2002, Vol 48, Num 2, pp 366-370, issn 0009-9147Article

Comparison of SLCO1B1 sequence variability among German, Turkish, and African populationsMWINYI, Jessica; KÖPKE, Karla; SCHAEFER, Melanie et al.European journal of clinical pharmacology. 2008, Vol 64, Num 3, pp 257-266, issn 0031-6970, 10 p.Article

Simultaneous determination of celecoxib, hydroxycelecoxib, and carboxycelecoxib in human plasma using gradient reversed-phase liquid chromatography with ultraviolet absorbance detectionSTÖRMER, Elke; BAUER, Steffen; KIRCHHEINER, Julia et al.Journal of chromatography. B, Biomedical sciences and applications. 2003, Vol 783, Num 1, pp 207-212, issn 1387-2273, 6 p.Article

Quantification of pravastatin in human plasma and urine after solid phase extraction using high performance liquid chromatography with ultraviolet detectionBAUER, Steffen; MWINYI, Jessica; STOECKLE, Angela et al.Journal of chromatography. B. 2005, Vol 818, Num 2, pp 257-262, issn 1570-0232, 6 p.Article

Contributions of CYP2D6, CYP2C9 and CYP2C19 to the biotransformation of E- and Z-doxepin in healthy volunteersKIRCHHEINERA, Julia; MEINEKE, Ingolf; MÜLLER, Gunnar et al.Pharmacogenetics (London). 2002, Vol 12, Num 7, pp 571-580, issn 0960-314X, 10 p.Article

Association of CYP1A1 polymorphisms with differential metabolic activation of 17β-estradiol and estroneKISSELEV, Pyotr; SCHUNCK, Wolf-Hagen; ROOTS, Ivar et al.Cancer research (Baltimore). 2005, Vol 65, Num 7, pp 2972-2978, issn 0008-5472, 7 p.Article

Determination of hyperforin, hypericin, and pseudohypericin in human plasma using high-performance liquid chromatography analysis with fluorescence and ultraviolet detectionBAUER, Steffen; STÖRMER, Elke; GRAUBAUM, Hans-Joachim et al.Journal of chromatography. B, Biomedical sciences and applications. 2001, Vol 765, Num 1, pp 29-35, issn 1387-2273Article

Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatmentTZVETKOV, Mladen Vassilev; BROCKMÖLLER, Jürgen; ROOTS, Ivar et al.Pharmacogenetics and genomics (Print). 2008, Vol 18, Num 6, pp 495-506, issn 1744-6872, 12 p.Article

Effect of genetic polymorphisms in cytochrome P450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs : Clinical relevanceKIRCHHEINER, Julia; ROOTS, Ivar; GOLDAMMER, Mark et al.Clinical pharmacokinetics. 2005, Vol 44, Num 12, pp 1209-1225, issn 0312-5963, 17 p.Article

Vitamin D receptor haplotypes protect against development of colorectal cancerFLIIGGE, Jana; KRUSEKOPF, Solveigh; GOLDAMMER, Mark et al.European journal of clinical pharmacology. 2007, Vol 63, Num 11, pp 997-1005, issn 0031-6970, 9 p.Article

Rapid genotyping of melanocortin-1 receptor with use of fluorescence-labeled oligonucleotidesDIEFENBACH, Konstanze; MROZIKIEWICZ, Przemyslaw M; BRIEN, Britta et al.Clinical chemistry (Baltimore, Md.). 2003, Vol 49, Num 3, pp 507-509, issn 0009-9147, 3 p.Article

MDR1 haplotypes do not affect the steady-state pharmacokinetics of cyclosporine in renal transplant patientsMAI, Ingrid; STÖRMER, Elke; GOLDAMMER, Mark et al.Journal of clinical pharmacology. 2003, Vol 43, Num 10, pp 1101-1107, issn 0091-2700, 7 p.Article

Pharmacoldnetics of levetiracetam in patients with moderate to severe liver cirrhosis (Child-Pugh classes A, B, and C) : Characterization by dynamic liver function testsBROCKMÖLLER, Jurgen; THOMSEN, Torben; WITTSTOCK, Marcus et al.Clinical pharmacology and therapeutics. 2005, Vol 77, Num 6, pp 529-541, issn 0009-9236, 13 p.Article

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