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Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistanceAZZARIA, M; SCHURR, E; GROS, P et al.Molecular and cellular biology (Print). 1989, Vol 9, Num 12, pp 5289-5297, issn 0270-7306, 9 p.Article

The chemistry of methotrexate and its analoguesRAHMAN, L. K. A; SIRI RAM CHANDRA.Medicinal research reviews (Print). 1988, Vol 8, Num 1, pp 95-155, issn 0198-6325Article

Structure-function analysis of thin filament proteins expressed in Escherichia coliHITCHCOCK-DEGREGORI, S. E.Cell motility and the cytoskeleton. 1989, Vol 14, Num 1, pp 12-20, issn 0886-1544, 9 p.Article

Chemical Substitutions That Introduce Activity Cliffs Across Different Compound Classes and Biological TargetsWASSERMANN, Anne Mai; BAJORATH, Jürgen.Journal of chemical information and modeling. 2010, Vol 50, Num 7, pp 1248-1256, issn 1549-9596, 9 p.Article

On a fragment approach to structure-activity correlationsRANDIC, M; JURS, P. C.Quantitative structure-activity relationships. 1989, Vol 8, Num 1, pp 39-48, issn 0931-8771, 10 p.Article

Colchicine and its analogues: recent findingsBROSSI, A; YEH, H. J. C; CHRZANOWSKA, M et al.Medicinal research reviews (Print). 1988, Vol 8, Num 1, pp 77-94, issn 0198-6325Article

Insights into Structure-Activity Relationships in the C-Terminal Region of Divercin V41, a Class IIa Bacteriocin with High-Level Antilisterial ActivityRIHAKOVA, Jitka; PETIT, Vanessa W; DEMNEROVA, Katerina et al.Applied and environmental microbiology (Print). 2009, Vol 75, Num 7, pp 1811-1819, issn 0099-2240, 9 p.Article

Structure-activity relationships of lactacystin, the first non-protein neurotrophic factorNAGAMITSU, T; SUNAZUKA, T; STUMP, H et al.Journal of antibiotics (Tokyo. 1968). 1995, Vol 48, Num 7, pp 747-748, issn 0021-8820Article

Beziehungen zwischen chemischer Struktur und antimykobakterieller Wirkung insbesondere gegen atypische Stämme. III: Oxalamidine, eine neue Gruppe von potentiellen Antituberkulotika = Relations structure chimique et activité antifongique/antibactérienne. III: Oxalamidine, un nouveau groupe d'antituberculeux potentiels = Relations between chemical structure and antifungal/antibacterial activity. III. Oxalamidine, a new class of potential antituberculous agentsWAISSER, K; ODLEROVA, Z; BECKERT, R et al.Pharmazie. 1989, Vol 44, Num 3, pp 234-235, issn 0031-7144Article

Correlation between the OH bond dissociation energies of ellipticine hydroxylated derivatives and their cytotoxic propertiesROUSSEAU-RICHARD, C; AUCLAIR, C; RICHARD, C et al.FEBS letters. 1989, Vol 252, Num 1-2, pp 58-62, issn 0014-5793, 5 p.Article

Studies on enteric anthelmintics: impact of single point structural change on the activity profileKHAN, A. M; GUPTA, S; KATIYAR, J. C et al.Zeitschrift für Naturforschung. B, A journal of chemical sciences. 1988, Vol 43, Num 2, pp 233-237, issn 0932-0776Article

Rationalizing Three-Dimensional Activity Landscapes and the Influence of Molecular Representations on Landscape Topology and the Formation of Activity CliffsPELTASON, Lisa; IYER, Preeti; BAJORATH, Jürgen et al.Journal of chemical information and modeling. 2010, Vol 50, Num 6, pp 1021-1033, issn 1549-9596, 13 p.Article

Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesisFLATMAN, Ruth H; EUSTAQUIO, Alessandra; LI, Shu-Ming et al.Antimicrobial agents and chemotherapy. 2006, Vol 50, Num 4, pp 1136-1142, issn 0066-4804, 7 p.Article

A strategy for ranking environmentally occurring chemicals. VI: QSARs for the mutagenic effects of halogenated aliphaticsERIKSSON, L; HELLBERG, S; JOHANSSON, E et al.Acta chemica scandinavica (Copenhagen. 1989). 1991, Vol 45, Num 9, pp 935-944, issn 0904-213XArticle

Selective and efficient syntheses of phototoxic 2,2':5',2''-terthiophene derivatives bearing a functional substituent in the 3'- or the 5-positionROSSI, R; CARPITA, A; CIOFALO, M et al.Tetrahedron (Oxford. Print). 1991, Vol 47, Num 39, pp 8443-8460, issn 0040-4020Article

La thrombomoduline : un nouveau protéoglycanne relation structure-fonction = Thrombomodulin: a new proteoglycanBOURIN, M. C.Annales de biologie clinique (Paris). 1991, Vol 49, Num 4, pp 199-207, issn 0003-3898Article

Anti-fluorescein antibodies as structure-function models to examine fundamental immunochemical and spectroscopic principlesVOSS, E. W.Comments on molecular and cellular biophysics. 1990, Vol 6, Num 4, pp 197-221, issn 0143-8123, 25 p.Article

Influence of neurophysin residues 1-8 on the optical activity of neurophysin-peptide complexes. Direct evidence that the 1-8 sequence alters the environment of bound peptideBRESLOW, E; CO, R. T; HANNA, P et al.International journal of peptide & protein research. 1989, Vol 34, Num 1, pp 21-27, issn 0367-8377Article

Somatostatin rand analogs lack splanchnic vasoconstrictive effects in anesthetized pigsCAMBRIA, R. P; NEVILLE, R; BALLANTYNE, G. H et al.The Journal of surgical research. 1987, Vol 43, Num 5, pp 452-459, issn 0022-4804Article

Aspects of the antituberculous activity of 27753-RP, a new semisynthetic derivative of griselimycineTOYOHARA, M.Annales de l'Institut Pasteur. Microbiologie. 1987, Vol 138, Num 6, pp 737-744, issn 0769-2609Article

Investigation of Structure-Activity Relationships of Oxyntomodulin (Oxm) Using Oxm AnalogsDRUCE, Maralyn R; MINNION, James S; FIELD, Benjamin C. T et al.Endocrinology (Philadelphia). 2009, Vol 150, Num 4, pp 1712-1721, issn 0013-7227, 10 p.Article

Navigating structure-activity IandscapesBAJORATH, Jürgen; PELTASON, Lisa; WAWER, Mathias et al.Drug discovery today. 2009, Vol 14, Num 13-14, pp 698-705, issn 1359-6446, 8 p.Article

Actin structure-function relationships in vitro using oligodeoxynucleotide-directed site-specific mutagenesisRUBENSTEIN, P. A; SOLOMON, L. R; SOLOMON, T et al.Cell motility and the cytoskeleton. 1989, Vol 14, Num 1, pp 35-39, issn 0886-1544, 5 p.Article

Synthesis and antihypertensive activity of some S-substituted 4H-1,2,4-triazolesEMILSSON, H; SELANDER, H; GAARDNER, J et al.Acta pharmaceutica suecica. 1987, Vol 24, Num 3, pp 123-134, issn 0001-6675Article

Perspectives on the past, present and future of computer prediction in toxicologyESDAILE, D. J.Toxicology letters. 1998, Vol 102-03, pp 609-610, issn 0378-4274Conference Paper

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