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Quantitative relationships between structure and pharmacokinetic parameters using molecular connectivity Chi indices. I: Substituted 2-sulfapyridinesREED, K; MEREISH, K; JENSEN, B et al.Journal of pharmaceutical sciences. 1984, Vol 73, Num 2, pp 237-240, issn 0022-3549Article

Stereoselective metabolism of conformational analogues of warfarin by β-naphthoflavone-inducible cytochrome P-450HEIMARK, L. D; TRAGER, W. F.Journal of medicinal chemistry (Print). 1985, Vol 28, Num 4, pp 503-506, issn 0022-2623Article

Bioactivation of prodrugs: structure-pharmacokinetic correlations of benzodiazepine estersMAKSAY, G; OTVOS, L; FISCHER, L. J et al.Drug metabolism reviews (Softcover ed.). 1983, Vol 14, Num 6, pp 1165-1192, issn 0360-2532Article

1-Aryl-piperazine as active metabolites of drugs with an aryl-piperazine side-chainCACCIA, S; FONG, M. H; GARATTINI, S et al.Biochemical pharmacology. 1985, Vol 34, Num 3, pp 393-394, issn 0006-2952Article

Relationship between molecular structure and cytochrome P450-metabolic intermediate complex formation, studied with orphenadrine analoguesBAST, A; SAVENIJE-CHAPEL, E; NOORDHOEK, J et al.Journal of pharmaceutical sciences. 1984, Vol 73, Num 7, pp 953-956, issn 0022-3549Article

Structure-pharmacokinetics relationship of quaternary ammonium compounds: elimination and distribution characteristicsNEEF, C; OOSTING, R; MEIJER, D. K. F et al.Naunyn-Schmiedeberg's archives of pharmacology. 1984, Vol 328, Num 2, pp 103-110, issn 0028-1298Article

Structure-metabolism relationships of ring-A halogenated analogues of 17α-ethynyloestradiolBONHAM, N. M; MAGGS, J. L; BULMAN-PAGE, P. C et al.Journal of steroid biochemistry and molecular biology. 1994, Vol 49, Num 2-3, pp 203-211, issn 0960-0760Article

Structure-affinity relationships between several new benzodiazepine derivatives and 3H-diazepam receptor sitesSHIBUYA, T; FIELD, R; WATANABE, Y et al.Japanese journal of pharmacology. 1984, Vol 34, Num 4, pp 435-440, issn 0021-5198Article

Substituent effects on the bioactivation of 2-(N-hydroxyacetamido)fluorenes by N-arylhydroxamic acid N,O-acyltransferaseELFARRA, A. A; HANNA, P. E.Journal of medicinal chemistry (Print). 1985, Vol 28, Num 10, pp 1453-1460, issn 0022-2623Article

Enzymic degradation of alginatesGACESA, P.International journal of biochemistry. 1992, Vol 24, Num 4, pp 545-552, issn 0020-711XArticle

N-alkyl barbiturates: a series of compounds for the study of metabolic structure-activity relationshipsTRESTON, A. M; HOOPER, W. D.Arzneimittel-Forschung. 1985, Vol 35, Num 11, pp 1627-1629, issn 0004-4172Article

Five mikanolide derivatives from Mikania cynanchifolia and their biogenetic relationshipsBOHLMANN, F; TSANKOVA, E; KING, R. M et al.Phytochemistry. 1984, Vol 23, Num 5, pp 1099-1101, issn 0031-9422Article

Quantitative relationships between structure and pharmacokinetics of beta-adrenoceptor blocking agents in manHINDERLING, P. H; SCHMIDLIN, O; SEYDEL, J. K et al.Journal of pharmacokinetics and biopharmaceutics. 1984, Vol 12, Num 3, pp 263-287, issn 0090-466XArticle

Quantitative relationships between structure and pharmacokinetics of beta-adrenoceptor blocing agents in manHINDERLING, P. H; SCHMIDLIN, O; SEYDEL, J. K et al.Journal of pharmacokinetics and biopharmaceutics. 1984, Vol 12, Num 6, pp 659-666, issn 0090-466XArticle

The effect of molecular weight on the bioavailability of heparinEMANUELE, R. M; FAREED, J.Thrombosis research. 1987, Vol 48, Num 5, pp 591-596, issn 0049-3848Article

Structure metabolism relationships (SMR) for the prediction of health hazards by the Environmental Protection Agency. I: Background for the practice of predictive toxicologyDI CARLO, F. J; BICKART, P; AUER, C. M et al.Drug metabolism reviews (Softcover ed.). 1986, Vol 17, Num 1-2, pp 171-184, issn 0360-2532Article

Structure-pharmacokinetics relationship of quaternary ammonium compounds: correlation of physicochemical and pharmacokinetic parametersNEEF, C; MEIJER, D. K. F.Naunyn-Schmiedeberg's archives of pharmacology. 1984, Vol 328, Num 2, pp 111-118, issn 0028-1298Article

Structure-pharmacodynamic-pharmacokinetic relationships of steroidal neuromuscular blocking agentsWIERDA, J. M. K. H; PROOST, J. H.European journal of anaesthesiology. Supplement. 1995, Num 11, pp 45-54, issn 0952-1941Article

Mechanism of the formation in vivo of α-phenyl-γ-lactones in the glutethimide seriesTARAKJI-KHALFH, Y; CAVE, C; MENAGER, S et al.European journal of medicinal chemistry. 1993, Vol 28, Num 7-8, pp 593-600, issn 0223-5234Article

Diastereomer-dependent substrate reduction properties of a dinitrogenase containing 1-fluorohomocitrate in the iron-molybdenum cofactorMADDEN, M. S; KINDON, N. D; LUDDEN, P. W et al.Proceedings of the National Academy of Sciences of the United States of America. 1990, Vol 87, Num 17, pp 6517-6521, issn 0027-8424, 5 p.Article

Conformational analysis of 9-substituted adenines in relation to their microsomal N1-oxidationSIU PING LAM; BARLOW, D. J; GORROD, J. W et al.Journal of pharmacy and pharmacology. 1989, Vol 41, Num 6, pp 373-378, issn 0022-3573Article

Stable acyl-derivatives of tissue-type plasminogen activatorSTÜRZEBECHER, J; RICHTER, M; MARKWARDT, F et al.Thrombosis research. 1987, Vol 47, Num 6, pp 699-703, issn 0049-3848Article

Adrenal medulla imaging agents: a structure-distribution relationship study of radiolabeled aralkylguanidinesWIELAND, D. M; MANGNER, T. J; INBASEKARAN, M. N et al.Journal of medicinal chemistry (Print). 1984, Vol 27, Num 2, pp 149-155, issn 0022-2623Article

Human insulin B24 (Phe→Ser): secretion and metabolic clearance of the abnormal insulin in man and in a dog modelSHOELSON, S. E; POLONSKY, K. S; ZEIDLER, A et al.The Journal of clinical investigation. 1984, Vol 73, Num 5, pp 1351-1358, issn 0021-9738Article

Shift of the high-performance liquid chromatographic retention times of metabolites in relation to the original drug on an RP8 column with acidic mobile phaseHERRE, S; PRAGST, F.Journal of chromatography. B, Biomedical sciences and applications. 1997, Vol 692, Num 1, pp 111-126, issn 1387-2273Article

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