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kw.\*:("Rho kinase inhibitor")

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A RHO KINASE (ROCK) INHIBITOR, FASUDIL, PREVENTS MATRIX METALLOPROTEINASE-9-RELATED HEMORRHAGIC TRANSFORMATION IN MICE TREATED WITH TISSUE PLASMINOGEN ACTIVATORISHIGURO, M; KAWASAKI, K; IWAMA, T et al.Neuroscience. 2012, Vol 220, pp 302-312, issn 0306-4522, 11 p.Article

Enhancement of Endothelial Progenitor Cell Numbers and Migration by H1152, a Rho Kinase Specific InhibitorO, Eunju; LEE, Seung Woo; LEE, Hyun-Sun et al.Bioscience, biotechnology, and biochemistry. 2012, Vol 76, Num 1, pp 172-175, issn 0916-8451, 4 p.Article

Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosisWASHIDA, Naoki; WAKINO, Shu; HAYASHI, Koichi et al.Nephrology, dialysis, transplantation (Print). 2011, Vol 26, Num 9, pp 2770-2779, issn 0931-0509, 10 p.Article

Structural insights into AGC kinase inhibitionBREITENLECHNER, Christine; GASSEL, Michael; ENGH, Richard et al.Oncology research. 2004, Vol 14, Num 6, pp 267-278, issn 0965-0407, 12 p.Article

Preventive and therapeutic effects of the selective Rho-kinase inhibitor fasudil on experimental autoimmune neuritisPINEDA, Arnold Angelo M; MINOHARA, Motozumi; KAWAMURA, Nobutoshi et al.Journal of the neurological sciences. 2011, Vol 306, Num 1-2, pp 115-120, issn 0022-510X, 6 p.Article

Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in ratsFUJII, Mutsumi; DURIS, Kamil; ALTAY, Orhan et al.Neurochemistry international. 2012, Vol 60, Num 3, pp 327-333, issn 0197-0186, 7 p.Article

Treatment of rat spinal cord injury with a Rho-kinase inhibitor and bone marrow stromal cell transplantationFURUYA, Takeo; HASHIMOTO, Masayuki; KODA, Masao et al.Brain research. 2009, Vol 1295, pp 192-202, issn 0006-8993, 11 p.Article

Involvement of RhoA and possible neuroprotective effect of fasudil, a Rho kinase inhibitor, in NMDA-induced neurotoxicity in the rat retinaKITAOKA, Yuka; KITAOKA, Yasushi; KUMAI, Toshio et al.Brain research. 2004, Vol 1018, Num 1, pp 111-118, issn 0006-8993, 8 p.Article

Super-selective intracoronary injection of Rho-kinase inhibitor relieves refractory coronary vasospasms: A case reportTANIGUCHI, Yousuke; FUNAYAMA, Hiroshi; MATSUDA, Jun et al.International journal of cardiology. 2014, Vol 176, Num 1, pp 270-271, issn 0167-5273, 2 p.Article

Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivoLINGOR, Paul; TEUSCH, Nicole; SCHWARZ, Katrin et al.Journal of neurochemistry. 2007, Vol 103, Num 1, pp 181-189, issn 0022-3042, 9 p.Article

Partial protective effect of Y-27632, a Rho kinase inhibitor, against hepatic ischemia-reperfusion injury in ratsKAWAGUCHI, Atsuhiro; OHMORI, Masami; FUJIMURA, Akio et al.European journal of pharmacology. 2004, Vol 493, Num 1-3, pp 167-171, issn 0014-2999, 5 p.Article

A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult catsSAGAWA, Hiroe; TERASAKI, Hiroko; NAKAMURA, Makoto et al.Experimental neurology (Print). 2007, Vol 205, Num 1, pp 230-240, issn 0014-4886, 11 p.Article

Rho Kinase Inhibitor Fasudil Protects against β-Amyloid-Induced Hippocampal Neurodegeneration in RatsYUN SONG; XU CHEN; WANG, Li-Yan et al.CNS neuroscience & therapeutics (Print). 2013, Vol 19, Num 8, pp 603-610, issn 1755-5930, 8 p.Article

Metastin Inhibits Migration and Invasion of Renal Cell Carcinoma with Overexpression of Metastin Receptor. CommentariesSHOJI, Sunao; XIAN YAN TANG; TERACHI, Toshiro et al.European urology. 2009, Vol 55, Num 2, pp 441-451, issn 0302-2838, 11 p.Article

Tumour necrosis factor-alpha increases extravasation of virus particles into tumour tissue by activating the Rho A/Rho kinase pathwaySEKI, Takahiro; CARROLL, Fionnadh; ILLINGWORTH, Sam et al.Journal of controlled release. 2011, Vol 156, Num 3, pp 381-389, issn 0168-3659, 9 p.Article

Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinaseKAST, R; SCHIROK, H; LOBELL, M et al.British journal of pharmacology. 2007, Vol 152, Num 7, pp 1070-1080, issn 0007-1188, 11 p.Article

A Practical Synthesis of (S)-tert-Butyl 3-Methyl-1,4-diazepane-1-carboxylate, the Key Intermediate of Rho―Kinase Inhibitor K-115GOMI, Noriaki; KOUKETSU, Akiyasu; OHGIYA, Tadaaki et al.Synthesis (Stuttgart). 2012, Num 20, pp 3171-3178, issn 0039-7881, 8 p.Article

Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor geneYASUDA, Tadashi; TADA, Yuji; TANABE, Nobuhiro et al.American journal of physiology. Lung cellular and molecular physiology. 2011, Vol 45, Num 5, issn 1040-0605, L667-L674Article

Inhalational Therapy for Pulmonary Arterial Hypertension: Current Status and Future ProspectsGUPTA, Vivek; AHSAN, Fakhrul.Critical reviews in therapeutic drug carrier systems. 2010, Vol 27, Num 4, pp 313-370, issn 0743-4863, 58 p.Article

Rho kinase inhibitor improves motor dysfunction and hypoalgesia in a rat model of lumbar spinal canal stenosisITO, Toshinori; OHTORI, Seiji; HATA, Katsuhiko et al.Spine (Philadelphia, PA. 1976). 2007, Vol 32, Num 19, pp 2070-2075, issn 0362-2436, 6 p.Article

Synthesis of potential Rho-kinase inhibitors based on the chemistry of an original heterocycle : 4,4-Dimethyl-3,4-dihydro-1H -quinolin-2-oneLETELLIER, Marie-Anne; GUILLARD, Jérome; CAIGNARD, Daniel-Henri et al.European journal of medicinal chemistry. 2008, Vol 43, Num 8, pp 1730-1736, issn 0223-5234, 7 p.Article

Fasudil protects hippocampal neurons against hypoxia― reoxygenation injury by suppressing microglial inflammatory responses in miceJING DING; LI, Qin-Ying; XIN WANG et al.Journal of neurochemistry. 2010, Vol 114, Num 6, pp 1619-1629, issn 0022-3042, 11 p.Article

Rho-kinase inhibitors decrease TGF-p-stimulated VEGF synthesis through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblastsKUNO, Masashi; TAKAI, Shinji; MATSUSHIMA-NISHIWAKI, Rie et al.Biochemical pharmacology. 2009, Vol 77, Num 2, pp 196-203, issn 0006-2952, 8 p.Article

Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 2, optimization for blood pressure reduction in spontaneously hypertensive ratsGINN, John D; BOSANAC, Todd; SCHLYER, Sabine et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 17, pp 5153-5156, issn 0960-894X, 4 p.Article

Novel drug targets for the pharmacotherapy of benign prostatic hyperplasia (BPH)VENTURA, S; OLIVER, V. L; WHITE, C. W et al.British journal of pharmacology. 2011, Vol 163, Num 5, pp 891-907, issn 0007-1188, 17 p.Article

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