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Results 1 to 25 of 32

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NMR studies of drug-DNA interactionsSEARLE, M. S.Progress in nuclear magnetic resonance spectroscopy. 1993, Vol 25, Num 5, pp 403-480, issn 0079-6565Article

Hoogsteen versus Watson-Crick A-T basepairing in DNA complexes of a new group of quinomycin-like antibioticsSEARLE, M. S; WICKHAM, G.FEBS letters. 1990, Vol 272, Num 1-2, pp 171-174, issn 0014-5793Article

Interaction of the anthracycline antibiotic nogalamycin with the hexamer duplex d(5'-GACGTC)2 : an NMR and molecular modelling studySEARLE, M. S; BICKNELL, W.European journal of biochemistry (Print). 1992, Vol 205, Num 1, pp 45-58, issn 0014-2956Article

Recognition of the cell-wall binding site of the vancomycin-group antibiotics by unnatural structural motifs : 1H NMR studies of the effects of ligand binding on antibiotic dimerisationGROVES, P; SEARLE, M. S; CHICARELLI-ROBINSON, I et al.Journal of the Chemical Society. Perkin transactions. I. 1994, Num 6, pp 659-665, issn 0300-922XArticle

Interaction of Hoechst 33258 with the minor groove of the A + T-rich DNA duplex d(GGTAATTACC)2 studied in solution by NMR spectroscopyEMBREY, K. J; SEARLE, M. S; CRAIK, D. J et al.European journal of biochemistry (Print). 1993, Vol 211, Num 3, pp 437-447, issn 0014-2956Article

Towards a semi-quantitative description of a biomolecular association involving weak interactions in aqueous solutionWILLIAMS, D. H; SEARLE, M. S; WESTWELL, M. S et al.Philosophical transactions-Royal Society of London. Physical sciences and engineering. 1993, Vol 345, Num 1674, pp 11-21, issn 0962-8428Article

Recreation Non-Participation and Barriers to Participation : Concepts and Models in Etudes canadiennes. Canadian StudiesJACKSON, E. L; SEARLE, M. S.Loisir et société. 1985, Vol 8, Num 2, pp 693-707, issn 0705-3436Article

Toward an estimation of binding constants in aqueous solution : studies of associations of vancomycin group antibioticsWILLIAMS, D. H; SEARLE, M. S; MACKAY, J. P et al.Proceedings of the National Academy of Sciences of the United States of America. 1993, Vol 90, Num 4, pp 1172-1178, issn 0027-8424Conference Paper

31P NMR investigation of the backbone conformation and dynamics of the hexamer duplex d(5'-GCATGC)2 in its complex with the antibiotic nogalamycinSEARLE, M. S; LANE, A. N.FEBS letters. 1992, Vol 297, Num 3, pp 292-296, issn 0014-5793Article

Consequences for molecular recognition and ligand-receptor complementarity of entropy changes in phase transitionsSEARLE, M. S; WILLIAMS, D. H.Bioorganic & medicinal chemistry letters. 1992, Vol 2, Num 9, pp 993-996Article

Dynamics of trimethoprim bound to dihydrofolate reductaseSEARLE, M. S; FORSTER, M. J; BIRDSALL, B et al.Proceedings of the National Academy of Sciences of the United States of America. 1988, Vol 85, Num 11, pp 3787-3791, issn 0027-8424Article

A new formula for population-based estimation of whole body muscle mass in malesDOUPE, M. B; MARTIN, A. D; SEARLE, M. S et al.Canadian journal of applied physiology. 1997, Vol 22, Num 6, pp 598-608, issn 1066-7814Article

Interaction of the antitumor antibiotic luzopeptin with the hexanucleotide duplex d('-GCATGC)2: one-dimensional and tow-dimensional n.m.r. studiesSEARLE, M. S; HALL, J. G; DENNY, W. A et al.Biochemical journal (London. 1906). 1989, Vol 259, Num 2, pp 433-441, issn 0006-2936Article

15N and 1H NMR evidence for multiple conformations of the complex of dihydrofolate reductase with its substrate, folateBIRDSALL, B; DE GRAW, J; FEENEY, J et al.FEBS letters. 1987, Vol 217, Num 1, pp 106-110, issn 0014-5793Article

Structural comparisons of complexes of methotrexate analogues with Lactobacillus casei dihydrofolate reductase by two-dimensional 1H NMR at 500 MHzHAMMOND, S. J; BIRDSALL, B; FEENEY, J et al.Biochemistry (Easton). 1987, Vol 26, Num 26, pp 8585-8590, issn 0006-2960Article

Identification of the 1H resonances of valine and leucine residues in dihydrofolate reductase by using a combination of selective deuteration and two-dimensional correlation spectroscopySEARLE, M. S; HAMMOND, S. J; BIRDSALL, B et al.FEBS letters. 1986, Vol 194, Num 1, pp 165-170, issn 0014-5793Article

Child abuse and neglect by parents with disabilities : a tale of two families : Current societal concernsGREENE, B. F; NORMAN, K. R; SEARLE, M. S et al.Journal of applied behavior analysis. 1995, Vol 28, Num 4, pp 417-434, issn 0021-8855Article

Rational design and binding of modified cell-wall peptides to vancomycin-group antibiotics : factorising free energy contributions to bindingHOLROYD, S. E; GROVES, P; SEARLE, M. S et al.Tetrahedron (Oxford. Print). 1993, Vol 49, Num 41, issn 0040-4020, v, 9171-9182 [13 p.]Article

Anthracycline antibiotic arugomycin binds in both grooves of the DNA helix simultaneously : an NMR and molecular modelling studySEARLE, M. S; BICKNELL, W; WAKELIN, L. P. G et al.Nucleic acids research. 1991, Vol 19, Num 11, pp 2897-2906, issn 0305-1048, 10 p.Article

Probing the interaction of Hoechst 33258 with an A-T rich oligonucleotide duplex using 1H NMR spectroscopyEMBREY, K. J; SEARLE, M. S; CRAIK, D. J et al.Journal of the Chemical Society. Chemical communications. 1991, Num 24, pp 1770-1771, issn 0022-4936Article

Conformation and dynamics of the deoxyribose rings of a 'nogalamycin2-d(5'GCATGC)2 complex studied in solution by 1H-n.m.r. spectroscopySEARLE, M. S; WAKELIN, L. P.Biochemical journal (London. 1906). 1990, Vol 269, Num 2, pp 341-346, issn 0006-2936, 6 p.Article

Sequence specific conformation of a DNA decamer containing and ademine tract studied in solution by 1 H-NMR spectroscopySEARLE, M. S; WAKELIN, L. P. G.Biochimica et biophysica acta. 1990, Vol 1049, Num 1, pp 69-77, issn 0006-3002, 9 p.Article

Didemnin B: conformation and dynamics of an antitumour and antiviral depsipeptide studied in solution by 1H and 13C n.m.r. spectroscopySEARLE, M. S; HALL, J. G; KYRATZIS, I et al.International journal of peptide & protein research. 1989, Vol 34, Num 6, pp 445-454, issn 0367-8377Article

1H- and 13C-n.m.r. studies of the antitumor antibiotic luzopeptin: resonancer assignments, conformation and flexibility in solutionSEARLE, M. S; HALL, J. G; WAKLEIN, L. P. G et al.Biochemical journal (London. 1906). 1988, Vol 256, Num 1, pp 271-278, issn 0006-2936Article

On the stability of nucleic acid structures in solution : enthalpy-entropy compensations, internal rotations and reversibilitySEARLE, M. S; WILLIAMS, D. H.Nucleic acids research. 1993, Vol 21, Num 9, pp 2051-2056, issn 0305-1048Article

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