NMR studies of drug-DNA interactionsSEARLE, M. S.Progress in nuclear magnetic resonance spectroscopy. 1993, Vol 25, Num 5, pp 403-480, issn 0079-6565Article

Hoogsteen versus Watson-Crick A-T basepairing in DNA complexes of a new group of quinomycin-like antibioticsSEARLE, M. S; WICKHAM, G.FEBS letters. 1990, Vol 272, Num 1-2, pp 171-174, issn 0014-5793Article

Interaction of the anthracycline antibiotic nogalamycin with the hexamer duplex d(5'-GACGTC)₂ : an NMR and molecular modelling studySEARLE, M. S; BICKNELL, W.European journal of biochemistry (Print). 1992, Vol 205, Num 1, pp 45-58, issn 0014-2956Article

Recognition of the cell-wall binding site of the vancomycin-group antibiotics by unnatural structural motifs : ¹H NMR studies of the effects of ligand binding on antibiotic dimerisationGROVES, P; SEARLE, M. S; CHICARELLI-ROBINSON, I et al.Journal of the Chemical Society. Perkin transactions. I. 1994, Num 6, pp 659-665, issn 0300-922XArticle

Interaction of Hoechst 33258 with the minor groove of the A + T-rich DNA duplex d(GGTAATTACC)₂ studied in solution by NMR spectroscopyEMBREY, K. J; SEARLE, M. S; CRAIK, D. J et al.European journal of biochemistry (Print). 1993, Vol 211, Num 3, pp 437-447, issn 0014-2956Article

Toward an estimation of binding constants in aqueous solution : studies of associations of vancomycin group antibioticsWILLIAMS, D. H; SEARLE, M. S; MACKAY, J. P et al.Proceedings of the National Academy of Sciences of the United States of America. 1993, Vol 90, Num 4, pp 1172-1178, issn 0027-8424Conference Paper

³¹P NMR investigation of the backbone conformation and dynamics of the hexamer duplex d(5'-GCATGC)₂ in its complex with the antibiotic nogalamycinSEARLE, M. S; LANE, A. N.FEBS letters. 1992, Vol 297, Num 3, pp 292-296, issn 0014-5793Article

Consequences for molecular recognition and ligand-receptor complementarity of entropy changes in phase transitionsSEARLE, M. S; WILLIAMS, D. H.Bioorganic & medicinal chemistry letters. 1992, Vol 2, Num 9, pp 993-996Article

Dynamics of trimethoprim bound to dihydrofolate reductaseSEARLE, M. S; FORSTER, M. J; BIRDSALL, B et al.Proceedings of the National Academy of Sciences of the United States of America. 1988, Vol 85, Num 11, pp 3787-3791, issn 0027-8424Article

A new formula for population-based estimation of whole body muscle mass in malesDOUPE, M. B; MARTIN, A. D; SEARLE, M. S et al.Canadian journal of applied physiology. 1997, Vol 22, Num 6, pp 598-608, issn 1066-7814Article

Interaction of the antitumor antibiotic luzopeptin with the hexanucleotide duplex d('-GCATGC)₂: one-dimensional and tow-dimensional n.m.r. studiesSEARLE, M. S; HALL, J. G; DENNY, W. A et al.Biochemical journal (London. 1906). 1989, Vol 259, Num 2, pp 433-441, issn 0006-2936Article

¹⁵N and ¹H NMR evidence for multiple conformations of the complex of dihydrofolate reductase with its substrate, folateBIRDSALL, B; DE GRAW, J; FEENEY, J et al.FEBS letters. 1987, Vol 217, Num 1, pp 106-110, issn 0014-5793Article

Structural comparisons of complexes of methotrexate analogues with Lactobacillus casei dihydrofolate reductase by two-dimensional ¹H NMR at 500 MHzHAMMOND, S. J; BIRDSALL, B; FEENEY, J et al.Biochemistry (Easton). 1987, Vol 26, Num 26, pp 8585-8590, issn 0006-2960Article

Identification of the ¹H resonances of valine and leucine residues in dihydrofolate reductase by using a combination of selective deuteration and two-dimensional correlation spectroscopySEARLE, M. S; HAMMOND, S. J; BIRDSALL, B et al.FEBS letters. 1986, Vol 194, Num 1, pp 165-170, issn 0014-5793Article

On the stability of nucleic acid structures in solution : enthalpy-entropy compensations, internal rotations and reversibilitySEARLE, M. S; WILLIAMS, D. H.Nucleic acids research. 1993, Vol 21, Num 9, pp 2051-2056, issn 0305-1048Article

Partitioning of free energy contributions in the estimation of binding constants : residual motions and consequences for amide-amide hydrogen bond strengthsSEARLE, M. S; WILLIAMS, D. H; GERHARD, U et al.Journal of the American Chemical Society. 1992, Vol 114, Num 27, pp 10697-10704, issn 0002-7863Article

The cost of conformational order : entropy changes in molecular associationsSEARLE, M. S; WILLIAMS, D. H.Journal of the American Chemical Society. 1992, Vol 114, Num 27, pp 10690-10697, issn 0002-7863Article

Sequence-specific interaction of hoescht 33258 with the minor groove of an adenine-tract DNA duplex studied in solution by ¹H NMR spectroscopySEARLE, M. S; EMBREY, K. J.Nucleic acids research. 1990, Vol 18, Num 13, pp 3753-3762, issn 0305-1048, 10 p.Article

Expression of electrostatic binding cooperativity in the recognition of cell-wall peptide analogues by vancomycin group antibioticsGROVES, P; SEARLE, M. S; WESTWELL, M. S et al.Journal of the Chemical Society. Chemical communications. 1994, Num 13, pp 1519-1520, issn 0022-4936Article

NMR studies of the interaction of the antibiotic nogalamycin with the hexadeoxyribonucleotide duplex d(5'-GCATGC)₂SEARLE, M. S; HALL, J. G; DENNY, W. A et al.Biochemistry (Easton). 1988, Vol 27, Num 12, pp 4340-4349, issn 0006-2960Article

Dihydrofolate reductase: ¹H-Resonance assignments and coenzyme-induced conformational changesHAMMOND, S. J; BIRDSALL, B; SEARLE, M. S et al.Journal of molecular biology. 1986, Vol 188, Num 1, pp 81-97, issn 0022-2836Article

Trimethoprim binding to Lactobacillus casei dihydrofolate reductase: a ¹³C NMR study using selectively ¹³C-enriched trimethoprimCHEUNG, H. T. A; SEARLE, M. S; FEENEY, J et al.Biochemistry (Easton). 1986, Vol 25, Num 8, pp 1925-1931, issn 0006-2960Article