Urachal carcinoma associated with increased carbohydrate antigen 19-9 and carcinoembryonic antigenKIKUNO, Nobuyuki; URAKAMI, Shinji; SHIGENO, Kazushi et al.The Journal of urology. 2001, Vol 166, Num 2, issn 0022-5347, p. 604Article

Human bladder tumors with 2-hit mutations of the tumor suppressor gene TSC1 and decreased expression of p27ADACHI, Hiroyuki; IGAWA, Mikio; SHIINA, Hiroaki et al.The Journal of urology. 2003, Vol 170, Num 2, pp 601-604, issn 0022-5347, 4 p., 1Article

Impact of a novel, extended approach of perineal radical prostatectomy on surgical margins in localized prostate cancerINOUE, Shogo; SHIINA, Hiroaki; SUMURA, Masahiro et al.BJU international (Papier). 2010, Vol 106, Num 1, pp 44-48, issn 1464-4096, 5 p.Article

Retrospective analysis of the distance betweer the neurovascular bundle and prostate cancer foci in radical prostatectomy specimens: its clinical implication in nerve-sparing surgeryINOUE, Shogo; SHIINA, Hiroaki; HIRAOKA, Takeo et al.BJU international (Papier). 2009, Vol 104, Num 8, pp 1085-1090, issn 1464-4096, 6 p.Article

Expression of the survivin gene in prostate cancer: Correlation with clinicopathological characteristics, proliferative activity and apoptosisKISHI, Hirofumi; IGAWA, Mikio; KIKUNO, Nobuyuki et al.The Journal of urology. 2004, Vol 171, Num 5, pp 1855-1860, issn 0022-5347, 6 p.Article

Decreased survival of prostate cancer cells in vitro by combined treatment of heat and an antioxidant inhibitor diethyldithiocarbamate (DDC)MORIYAMA-GONDA, Nobuko; IGAWA, Mikio; SHIINA, Hiroaki et al.Experimental and toxicologic pathology (Print). 2003, Vol 55, Num 4, pp 251-256, issn 0940-2993, 6 p.Article

Polymorphisms of catechol-O -methyltransferase in men with renal cell cancerTANAKA, Yuichiro; HIRATA, Hiroshi; DHIR, Rajiv et al.Cancer epidemiology, biomarkers & prevention. 2007, Vol 16, Num 1, pp 92-97, issn 1055-9965, 6 p.Article

Increased Heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancerOGISHIMA, Tatsuya; SHIINA, Hiroaki; TERASHIMA, Masaharu et al.Clinical cancer research. 2005, Vol 11, Num 3, pp 1028-1036, issn 1078-0432, 9 p.Article

Methylation of the γ-Catenin gene is associated with poor prognosis of renal cell carcinomaBREAULT, Julia E; SHIINA, Hiroaki; CARROLL, Peter R et al.Clinical cancer research. 2005, Vol 11, Num 2, pp 557-564, issn 1078-0432, 8 p., 1Article

Promoter CpG hypomethylation and transcription factor EGR1 hyperactivate heparanase expression in bladder cancerOGISHIMA, Tatsuya; SHIINA, Hiroaki; FUJIME, Makoto et al.Oncogene (Basingstoke). 2005, Vol 24, Num 45, pp 6765-6772, issn 0950-9232, 8 p.Article

Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cellsKIKUNO, Nobuyuki; SHIINA, Hiroaki; URAKAMI, Shinji et al.International journal of cancer. 2008, Vol 123, Num 3, pp 552-560, issn 0020-7136, 9 p.Article

Smoking influences aberrant CpG hypermethylation of multiple genes in human prostate CarcinomaENOKIDA, Hideki; SHIINA, Hiroaki; IGAWA, Mikio et al.Cancer. 2006, Vol 106, Num 1, pp 79-86, issn 0008-543X, 8 p.Article

WT1 and WT1-AS genes are inactivated by promoter methylation in ovarian clear cell adenocarcinomaKANEUCHI, Masanori; SASAKI, Masahiro; TANAKA, Yuichiro et al.Cancer. 2005, Vol 104, Num 9, pp 1924-1930, issn 0008-543X, 7 p.Article

Androgen, estrogen, and progesterone receptor gene regulation during diabetic erectile dysfunction and insulin treatmentSHIRAI, Masato; YAMANAKA, Masaki; SHIINA, Hiroaki et al.Urology (Ridgewood, NJ). 2004, Vol 64, Num 6, pp 1244-1249, issn 0090-4295, 6 p.Article

Diabetes induced erectile dysfunction and apoptosis in penile crura are recovered by insulin treatment in ratsYAMANAKA, Masaki; SHIRAI, Masato; SHIINA, Hiroaki et al.The Journal of urology. 2003, Vol 170, Num 1, pp 291-297, issn 0022-5347, 7 p.Article

Overexpression of rat heat shock protein 70 is associated with reduction of early mitochondrial cytochrome c release and subsequent DNA fragmentation after permanent focal ischemiaTSUCHIYA, Daisuke; HONG, Shwuhuey; MATSUMORI, Yasuhiko et al.Journal of cerebral blood flow and metabolism. 2003, Vol 23, Num 6, pp 718-727, issn 0271-678X, 10 p.Article

Tumor Suppressor Function of PGP9.5 Is Associated with Epigenetic Regulation in Prostate Cancer—Novel Predictor of Biochemical Recurrence after Radical SurgeryMITSUI, Yozo; SHIINA, Hiroaki; HIRAKI, Miho et al.Cancer epidemiology, biomarkers & prevention. 2012, Vol 21, Num 3, pp 487-496, issn 1055-9965, 10 p.Article

Nerve growth factor combined with vascular endothelial growth factor enhances regeneration of bladder acellular matrix graft in spinal cord injury-induced neurogenic rat bladderKIKUNO, Nobuyuki; KAWAMOTO, Ken; TANAGHO, Emil et al.BJU international (Papier). 2009, Vol 103, Num 10, pp 1424-1428, issn 1464-4096, 5 p.Article

Combination analysis of hypermethylated wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detectionURAKAMI, Shinji; SHIINA, Hiroaki; DAHIYA, Rajvir et al.Clinical cancer research. 2006, Vol 12, Num 7, pp 2109-2116, issn 1078-0432, 8 p., 1Article

Epigenetic inactivation of the dioxin-responsive Cytochrome P4501A1 gene in human prostate cancerOKINO, Steven T; POOKOT, Deepa; LI, Long-Cheng et al.Cancer research (Baltimore). 2006, Vol 66, Num 15, pp 7420-7428, issn 0008-5472, 9 p.Article

Epigenetic inactivation of wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/β-catenin signaling pathwayURAKAMI, Shinji; SHIINA, Hiroaki; KIKUNO, Nobuyuki et al.Clinical cancer research. 2006, Vol 12, Num 2, pp 383-391, issn 1078-0432, 9 p.Article

Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNAURAKAMI, Shinji; SHIINA, Hiroaki; IGAWA, Mikio et al.Clinical cancer research. 2006, Vol 12, Num 23, pp 6989-6997, issn 1078-0432, 9 p.Article

CpG methylation at promoter site - : 140 inactivates TGFβ2 receptor gene in prostate cancerHONG ZHAO; SHIINA, Hiroaki; GREENE, Kirsten L et al.Cancer. 2005, Vol 104, Num 1, pp 44-52, issn 0008-543X, 9 p.Article

CpG hypermethylation of MDR1 gene contributes to the pathogenesis and progression of human prostate cancerENOKIDA, Hideki; SHIINA, Hiroaki; VERMA, Mukesh et al.Cancer research (Baltimore). 2004, Vol 64, Num 17, pp 5956-5962, issn 0008-5472, 7 p.Article

The role of Thymidine phosphorylase (TP) mRNA expression in angiogenesis of prostate cancerKIKUNO, Nobuyuki; YOSHINO, Tateki; URAKAMI, Shinji et al.Anticancer research. 2003, Vol 23, Num 2B, pp 1305-1312, issn 0250-7005, 8 p.Article