A GENETIC SYSTEM FOR ANALYSIS OF STAPHYLOCOCCAL NUCLEASESHORTLE D.1983; GENE; ISSN 0378-1119; NLD; DA. 1983; VOL. 22; NO 2-3; PP. 181-189; BIBL. 30 REF.Article

LOCAL MUTAGENESIS: A METHOD FOR GENERATING VIRAL MUTANTS WITH BASE SUBSTITUTION IN PRESELECTED REGIONS OF THE VIRAL GENOMESHORTLE D; NATHANS D.1978; PROC. NATION. ACAD. SCI. U.S.A.; USA; DA. 1978; VOL. 75; NO 5; PP. 2170-2174; BIBL. 28 REF.Article

REGULATORY MUTANTS OF SIMIAN VIRUS 40: CONSTRUCTED MUTANTS WITH BASE SUBSTITUTIONS AT THE ORIGIN OF DNA REPLICATIONSHORTLE D; NATHANS D.1979; J. MOLEC. BIOL.; GBR; DA. 1979; VOL. 131; NO 4; PP. 801-807; BIBL. 31 REF.Article

Mutational studies of protein structures and their stabilitiesSHORTLE, D.Quarterly Reviews of Biophysics. 1992, Vol 25, Num 2, pp 205-250, issn 0033-5835Article

Probing the determinants of protein folding and stability with amino acid substitutionsSHORTLE, D.The Journal of biological chemistry (Print). 1989, Vol 264, Num 10, pp 5315-5318, issn 0021-9258Article

LETHAL DISRUPTION OF THE YEAST ACTIN GENE BY INTEGRATIVE DNA TRANSFORMATIONSHORTLE D; HABER JE; BOTSTEIN D et al.1982; SCIENCE; ISSN 0036-8075; USA; DA. 1982; VOL. 217; NO 4557; PP. 371-373; BIBL. 16 REF.Article

DIRECTED MUTAGENESIS = MUTAGENESE DIRIGEESHORTLE D; DI MAIO D; NATHANS D et al.1981; ANNU. REV. GENET.; ISSN 0066-4197; USA; DA. 1981; VOL. 15; PP. 265-294; BIBL. 5 P.Article

TRAPPING OF A NOVEL COENZYME A CONTAINING INTERMEDIATE OF 3-HYDROXY-3-METHYLGLUTARYL-COA SYNTHASE.MIZIORKO HM; SHORTLE D; LANE D et al.1976; BIOCHEM. BIOPHYS. RES. COMMUNIC.; U.S.A.; DA. 1976; VOL. 69; NO 1; PP. 92-98; BIBL. 6 REF.Article

Strategies and applications of in vitro mutagenesisBOTSTEIN, D; SHORTLE, D.Science (Washington, D.C.). 1985, Vol 229, Num 4719, pp 1193-1201, issn 0036-8075Article

Accommodation of single amino acid insertions by the native state of staphylococcal nucleaseSONDEK, J; SHORTLE, D.Proteins. 1990, Vol 7, Num 4, pp 299-305, issn 0887-3585, 7 p.Article

Structural and energetic differences between insertions and substitutions in staphylococcal nucleaseSONDEK, J; SHORTLE, D.Proteins. 1992, Vol 13, Num 2, pp 132-140, issn 0887-3585Article

CONSTRUCTED MUTANTS OF SIMIAN VIRUS 40SHORTLE D; PIPAS J; LAZAROWITZ S et al.1979; GENET. ENG; USA; DA. 1979; VOL. 1; PP. 73-92; BIBL. 38 REF.Article

Null alleles of SAC7 suppress temperature-sensitive actin mutations in Saccharomyces cerevisiaeDUNN, T. M; SHORTLE, D.Molecular and cellular biology (Print). 1990, Vol 10, Num 5, pp 2308-2314, issn 0270-7306, 7 p.Article

Construction and genetic characterization of temperature-sensitive mutant alleles of the yeast actin geneSHORTLE, D; NOVICK, P; BOTSTEIN, D et al.Proceedings of the National Academy of Sciences of the United States of America. Biological sciences. 1984, Vol 81, Num 15, pp 4889-4893, issn 0273-1134Article

Effects of denaturants at low concentrations on the reversible denaturation of staphylococcal nucleaseSHORTLE, D; MEEKER, A. K; GERRING, S. L et al.Archives of biochemistry and biophysics (Print). 1989, Vol 272, Num 1, pp 103-113, issn 0003-9861Article

Isolation and sequencing of the gene encoding △⁵-3-ketosteroid isomerase of Pseudomonas testosteroni: overexpression of the proteinKULIOPULOS, A; SHORTLE, D; TALALAY, P et al.Proceedings of the National Academy of Sciences of the United States of America. 1987, Vol 84, Num 24, pp 8893-8897, issn 0027-8424Article

Kinetic and magnetic resonance studies of effects of genetic substitution of a Ca²⁺-liganding amino acid in staphylococcal nucleaseSERPERSU, E. H; SHORTLE, D; MILDVAN, A. S et al.Biochemistry (Easton). 1986, Vol 25, Num 1, pp 68-77, issn 0006-2960Article

Mutagenesis of cloned genesBOTSTEIN, D; SHORTLE, D; ROSE, M et al.International symposium on genetics of industrial microorganisms. 4. 1983, pp 169-172Conference Paper

Evidence for strained interactions between side-chains and the polypeptide backboneSTITES, W. E; MEEKER, A. K; SHORTLE, D et al.Journal of molecular biology. 1994, Vol 235, Num 1, pp 27-32, issn 0022-2836Article

Structure and dynamics of a denatured 131-residue fragment of staphylococcal nuclease : a heteronuclear NMR studyALEXANDRESCU, A. T; CHITRANANDA ABEYGUNAWARDANA; SHORTLE, D et al.Biochemistry (Easton). 1994, Vol 33, Num 5, pp 1063-1072, issn 0006-2960Article

Contributions of the polar, uncharged amino acids to the stability of staphylococcal nuclease : evidence for mutational effects on the free energy of the denatured stateGREEN, S. M; MEEKER, A. K; SHORTLE, D et al.Biochemistry (Easton). 1992, Vol 31, Num 25, pp 5717-5728, issn 0006-2960Article

Stability mutants of staphylococcal nuclease: large compensating enthalpy-entropy changes for the reversible denaturation reactionSHORTLE, D; MEEKER, A. K; FREIRE, R et al.Biochemistry (Easton). 1988, Vol 27, Num 13, pp 4761-4768, issn 0006-2960Article

Truncated staphylococcal nuclease is compact but disorderedFLANAGAN, J. M; KATAOKA, M; SHORTLE, D et al.Proceedings of the National Academy of Sciences of the United States of America. 1992, Vol 89, Num 2, pp 748-752, issn 0027-8424Article

The α aneurism : a structural motif revealed in an insertion mutant of staphylococcal nucleaseKEEFE, L. J; SONDEK, J; SHORTLE, D et al.Proceedings of the National Academy of Sciences of the United States of America. 1993, Vol 90, Num 8, pp 3275-3279, issn 0027-8424Article

Crystallization and preliminary X-ray analysis of quadruple mutant of staphylococcal nucleaseLOLL, P. J; MEEKER, A. K; SHORTLE, D et al.The Journal of biological chemistry (Print). 1988, Vol 263, Num 34, pp 18190-18192, issn 0021-9258Article