Aminopyridine-based c-jun n-terminal kinase inhibitors with cellular activity and minimal cross-kinase activitySZCZEPANKIEWICZ, Bruce G; KOSOGOF, Christi; HAASCH, Deanna L et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 12, pp 3563-3580, issn 0022-2623, 18 p.Article

Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitorsZHONGHUA PEI; XIAOFENG LI; MIKA, Amanda K et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 12, pp 3520-3535, issn 0022-2623, 16 p.Article

Nonsteroidal selective glucocorticoid modulators: The effect of C-10 substitution on receptor selectivity and functional potency of 5-allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolinesKYM, Philip R; KORT, Michael E; FALLS, H. Douglass et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 6, pp 1016-1030, issn 0022-2623, 15 p.Article

Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]-4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279) : A very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetesMADAR, David J; KOPECKA, Hana; BHAGAVATULA, Lakshmi et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 21, pp 6416-6420, issn 0022-2623, 5 p.Article

Discovery of a potent, selective Protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategySZCZEPANKIEWICZ, Bruce G; GANG LIU; HENG LIANG et al.Journal of the American Chemical Society. 2003, Vol 125, Num 14, pp 4087-4096, issn 0002-7863, 10 p.Article

Identification of a monoacid-based, cell permeable, selective inhibitor of protein tyrosine phosphatase 1BZHILI XIN; GANG LIU; STASHKO, Michael A et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 22, pp 3947-3950, issn 0960-894X, 4 p.Article

Discovery of ((4R,5S)-5-amino-4-(2,4,5-trifluorophenyl)cyclohex-1-enyl)-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetesZHONGHUA PEI; XIAOFENG LI; JUDD, Andrew S et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 22, pp 6439-6442, issn 0022-2623, 4 p.Article

Selective protein tyrosine phosphatase 1B inhibitors: Targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligandsGANG LIU; ZHILI XIN; STASHKO, Michael A et al.Journal of medicinal chemistry (Print). 2003, Vol 46, Num 16, pp 3437-3440, issn 0022-2623, 4 p.Article

Nonsteroidal selective glucocorticoid modulators: the effect of C-5 alkyl substitution on the transcriptional activation/repression profile of 2,5-dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolinesELMORE, Steven W; COGHLAN, Michael J; JACOBSON, Peer B et al.Journal of medicinal chemistry (Print). 2001, Vol 44, Num 25, pp 4481-4491, issn 0022-2623Article