Hematopoietic Cell Transplantation for Tolerance Induction : Animal Models to Clinical TrialsSYKES, Megan.Transplantation. 2009, Vol 87, Num 3, pp 309-316, issn 0041-1337, 8 p.Article

Mechanisms of Transplantation Tolerance in Animals and HumansSYKES, Megan.Transplantation. 2009, Vol 87, Num 9S, issn 0041-1337, S67-S69, SUPConference Paper

Mixed chimerism and transplantation toleranceWEKERLE, Thomas; SYKES, Megan.Annual review of medicine. 2001, Vol 52, pp 353-370, issn 0066-4219Article

Mixed hematopoietic chimerism for the simultaneous induction of T and B cell toleranceSYKES, Megan; SHIMIZU, Ichiro; KAWAHARA, Toshiyasu et al.Transplantation. 2005, Vol 79, Num 3, pp S28-S29, issn 0041-1337, SUPConference Paper

Local irradiation enhances congenic donor pluripotent hematopoietic stem cell engraftment similarly in irradiated and nonirradiated sitesITO, Hiroshi; TAKEUCHI, Yasuo; SHAFFER, Juanita et al.Blood. 2004, Vol 103, Num 5, pp 1949-1954, issn 0006-4971, 6 p.Article

Donor lymphocyte infusion-mediated graft-versus-leukemia effects in mixed chimeras established with a nonmyeloablative conditioning regimen: Extinction of graft-versus-leukemia effects after conversion to full donor chimerismMAPARA, Markus Y; KIM, Yong-Mi; MARX, Julie et al.Transplantation. 2003, Vol 76, Num 2, pp 297-305, issn 0041-1337, 9 p.Article

4.Non-myeloblative induction of mixed hematopoietic chimerism: Application to transplantation tolerance and hematologic malignancies in experimental and clinical studiesSYKES, Megan; SPITZER, Thomas R.Cancer treatment and research. 2002, Vol 110, pp 79-99, issn 0927-3042, 21 p.Article

Donor-derived interferon γ separates graft-versus-leukemia effects and graft-versus-host disease induced by donor CD8 T cellsYANG, Yong-Guang; QI, Jin; WANG, Min-Guang et al.Blood. 2002, Vol 99, Num 11, pp 4207-4215, issn 0006-4971Article

Mixed chimerism induces donor-specific T-cell tolerance across a highly disparate xenogeneic barrierABE, Masahiro; JIN QI; SYKES, Megan et al.Blood. 2002, Vol 99, Num 10, pp 3823-3829, issn 0006-4971Article

CTLA-4 on alloreactive CD4 T cells interacts with recipient CD80/86 to promote toleranceKURTZ, Josef; RAVAL, Forum; VALLOT, Casey et al.Blood. 2009, Vol 113, Num 15, pp 3475-3484, issn 0006-4971, 10 p.Article

Mechanisms of early peripheral CD4 T-cell tolerance induction by anti-CD 154 monoclonal antibody and allogeneic bone marrow transplantation: evidence for anergy and deletion but not regulatory cellsKURTZ, Josef; SHAFFER, Juanita; LIE, Ariadne et al.Blood. 2004, Vol 103, Num 11, pp 4336-4343, issn 0006-4971, 8 p.Article

Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunityNIKOLIC, Boris; TAKEUCHI, Yasno; LEYKIN, Igor et al.Diabetes (New York, NY). 2004, Vol 53, Num 2, pp 376-383, issn 0012-1797, 8 p.Article

Despite efficient intrathymic negative selection of host-reactive T cells, autoimmune disease may develop in porcine thymus-grafted athymic mice: Evidence for failure of regulatory mechanisms suppressing autoimmunityYONG ZHAO; RODRIGUEZ-BARBOSA, Jose-Ignacio; SHIMIZU, Akira et al.Transplantation. 2003, Vol 75, Num 11, pp 1832-1840, issn 0041-1337, 9 p.Article

B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-αGAL-producing B-1 cellsSHIMIZU, Ichiro; KAWAHARA, Toshiyasu; HASPOT, Fabienne et al.Blood. 2007, Vol 109, Num 4, pp 1773-1781, issn 0006-4971, 9 p.Article

Cell therapy with preimmunized effector cells mismatched for minor histocompatible antigens in the treatment of a murine mammary carcinoma. CommentarySYKES, Megan; MORECKI, Shoshana; YACOVLEV, Elena et al.Journal of immunotherapy (1997). 2001, Vol 24, Num 2, pp 101-103, issn 1524-9557, 11 p.Article

Decay-accelerating factor prevents acute humoral rejection induced by low levels of anti-αGal natural antibodiesSHIMIZU, Ichiro; SMITH, Neal R; GUILING ZHAO et al.Transplantation. 2006, Vol 81, Num 1, pp 95-100, issn 0041-1337, 6 p.Article

Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-γRUBIO, Marie-Therese; KIM, Yong-Mi; SACHS, Teviah et al.Blood. 2003, Vol 102, Num 6, pp 2300-2307, issn 0006-4971, 8 p.Article

Minimal conditioning required in a murine model of T cell depletion, thymic irradiation and high-dose bone marrow transplantation for the induction of mixed chimerism and toleranceWEKERLE, Thomas; NIKOLIC, Boris; PEARSON, Denise A et al.Transplant international. 2002, Vol 15, Num 5, pp 248-253, issn 0934-0874Article

Comparison of Human T Cell Repertoire Generated in Xenogeneic Porcine and Human Thymus GraftsSHIMIZU, Ichiro; FUDABA, Yasuhiro; SHIMIZU, Akira et al.Transplantation. 2008, Vol 86, Num 4, pp 601-610, issn 0041-1337, 10 p.Article

T cell and B cell tolerance to galα1,3gal-expressing heart xenografts is achieved in α1,3-galactosyltransferase-deficient mice by nonmyeloablative induction of mixed chimerism¹OHDAN, Hideki; YANG, Yong-Guang; SWENSON, Kirsten G et al.Transplantation. 2001, Vol 71, Num 11, pp 1532-1542, issn 0041-1337, 11 p.Article

Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathwayHASPOT, Fabienne; FEHR, Thomas; GIBBONS, Carrie et al.Blood. 2008, Vol 112, Num 5, pp 2149-2155, issn 0006-4971, 7 p.Article

Joint Conference of the Cell Transplant Society (CTS), International Pancreas and Islet Transplant Association (IPITA), and International Xenotransplantation Association (IXA), Sections of the Transplantation Society (TTS)HERING, Bernhard J; SYKES, Megan; SUTHERLAND, David E. R et al.Transplantation proceedings. 2008, Vol 40, Num 2, issn 0041-1345, 320 p.Conference Proceedings

Both Innate and Adaptive Major Histocompatibility Complex Class I-Dependent Immunity Impair Long-Term Islet Xenograft SurvivalRAMIREZ-VICTORIO, F; BEILKE, J. N; GILL, R. G et al.Transplantation proceedings. 2008, Vol 40, Num 2, pp 557-558, issn 0041-1345, 2 p.Conference Paper

CDNA Cloning, Protein Structure Modeling of Rhesus Monkey (Macaca mulatta) ProthrombinQIN, S. F; TAN, W. D; CHEN, Y. N et al.Transplantation proceedings. 2008, Vol 40, Num 2, pp 603-606, issn 0041-1345, 4 p.Conference Paper

Heterogeneity of Human Pancreata in Perspective of the Isolation of the Islets of LangerhansTONS, H. A. M; TERPSTRA, O. T; BOUWMAN, E et al.Transplantation proceedings. 2008, Vol 40, Num 2, pp 367-369, issn 0041-1345, 3 p.Conference Paper