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Central serotonin transporter levels are associated with stress hormone response and anxietyREIMOLD, Matthias; KNOBEL, Astrid; GOLDMAN, David et al.Psychopharmacologia. 2011, Vol 213, Num 2-3, pp 563-572, issn 0033-3158, 10 p.Article

Synthesis and pharmacological evaluation of novel fused thiophene derivatives as 5-HT2A receptor antagonists: Molecular modeling studyEI-KERDAWY, Mohamed M; EL-BENDARY, Eman R; ABDEL-AZIZ, Alaa A.-M et al.European journal of medicinal chemistry. 2010, Vol 45, Num 5, pp 1805-1820, issn 0223-5234, 16 p.Article

Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2c and 5-HT6 receptor ligandsKROGSGAARD-LARSEN, N; JENSEN, A. A; KEHLER, J et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 18, pp 5431-5433, issn 0960-894X, 3 p.Article

Novel structural insights for drug design of selective 5-HT2C inverse agonists from a ligand-biased receptor modelRENAULT, Nicolas; GOHIER, Arnaud; CHAVATTE, Philippe et al.European journal of medicinal chemistry. 2010, Vol 45, Num 11, pp 5086-5099, issn 0223-5234, 14 p.Article

QSAR studies of bioactivities of 1-(azacyclyl)-3-arylsulfonyl-1H-pyrrolo[2,3-b] pyridines as 5-HT6 receptor ligands using physicochemical descriptors and MLR and ANN-modelingGOODARZI, Mohammad; FREITAS, Matheus P; GHASEMI, Nahid et al.European journal of medicinal chemistry. 2010, Vol 45, Num 9, pp 3911-3915, issn 0223-5234, 5 p.Article

Application of desirability-based multi(bi)-objective optimization in the design of selective arylpiperazine derivates for the 5-HT1A serotonin receptorMACHADO, A; TEJERA, E; CRUZ-MONTEAGUDO, M et al.European journal of medicinal chemistry. 2009, Vol 44, Num 12, pp 5045-5054, issn 0223-5234, 10 p.Article

Synthesis and Characterization of Environment-Sensitive Fluorescent Ligands for Human 5-HT1A Receptors with 1-Arylpiperazine StructureLACIVITA, Enza; LEOPOLDO, Marcello; CARMELA MASOTTI, Anna et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 23, pp 7892-7896, issn 0022-2623, 5 p.Article

A chemometric study of the 5-HT1A receptor affinities presented by arylpiperazine compoundsWEBER, Karen C; DA SILVA, Albérico B. F.European journal of medicinal chemistry. 2008, Vol 43, Num 2, pp 364-372, issn 0223-5234, 9 p.Article

Design and Synthesis of 2-and 3-Substituted-3-phenylpropyl Analogs of 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine : Role of Amino, Fluoro, Hydroxyl, Methoxyl, Methyl, Methylene, and Oxo Substituents on Affinity for the Dopamine and Serotonin TransportersHSIN, Ling-Wei; CHANG, Li-Te; ROTHMAN, Richard B et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 9, pp 2795-2806, issn 0022-2623, 12 p.Article

Designing rapid onset selective serotonin re-uptake inhibitors. 2: Structure-activity relationships of substituted (aryl)benzylaminesMIDDLETON, Donald S; ANDREWS, Mark; STOBIE, Alan et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 14, pp 4018-4021, issn 0960-894X, 4 p.Article

Computational Approaches for the Study of Serotonin and Its Membrane Transporter SERT : Implications for Drug Design in Neurological SciencesPRATUANGDEJKULL, J; SCHNEIDER, B; LAUNAY, J.-M et al.Current medicinal chemistry. 2008, Vol 15, Num 30, pp 3214-3227, issn 0929-8673, 14 p.Article

Designing rapid onset selective serotonin re-uptake inhibitors. Part 3. Site-directed metabolism as a strategy to avoid active circulating metabolites : Structure-activity relationships of (thioalkyl)phenoxy benzylaminesMIDDLETON, Donald S; ANDREWS, Mark; MORGAN, Paul et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 19, pp 5303-5306, issn 0960-894X, 4 p.Article

Development of 3-Phenyltropane Analogues with High Affinity for the Dopamine and Serotonin Transporters and Low Affinity for the Norepinephrine TransporterCHUNYANG JIN; NAVARRO, Hernan A; CARROLL, F. Ivy et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 24, pp 8048-8056, issn 0022-2623, 9 p.Article

Docking study, synthesis, and in vitro evaluation of fluoro-MADAM derivatives as SERT ligands for PET imagingMAVEL, Sylvie; VERCOUILLIE, Johnny; GARREAU, Lucette et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 19, pp 9050-9055, issn 0968-0896, 6 p.Article

Novel 5-HT1A/1B/1D receptors antagonists with potent 5-HT reuptake inhibitory activitySERAFINOWSKA, Halina T; BLANEY, Frank E; LOVELL, Peter J et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 20, pp 5581-5585, issn 0960-894X, 5 p.Article

A novel, non-substrate-based series of glycine type 1 transporter inhibitors derived from high-throughput screeningLOWE, J; DROZDA, S; SCHMIDT, A et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 6, pp 1675-1678, issn 0960-894X, 4 p.Article

Further studies on the binding of N1-substituted tryptamines at h5-HT6 receptorsNYANDEGE, Abner; KOLANOS, Renata; ROTH, Bryan L et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 6, pp 1691-1694, issn 0960-894X, 4 p.Article

Multistructure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-GT2A receptorDEZI, Cristina; BREA, José; ALVARADO, Mario et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 14, pp 3242-3255, issn 0022-2623, 14 p.Article

New fluoro-diphenylchalcogen derivatives to explore the serotonin transporter by PETVERCOUILLIE, Johnny; DEUTHER-CONRAD, Winnie; SCHEUNEMANN, Matthias et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 17, pp 4991-4995, issn 0960-894X, 5 p.Article

C-(4,5,6-trimethoxyindan-1-yl)methanamine : A mescaline analogue designed using a homology model of the 5-HT2A receptorMCLEAN, Thomas H; CHAMBERS, James J; PARRISH, Jason C et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 14, pp 4269-4274, issn 0022-2623, 6 p.Article

Homology modeling of the serotonin 5-HT1A receptor using automated docking of bioactive compounds with defined geometryNOWAK, Mateusz; KOLACZKOWSKI, Marcin; PAWŁOWSKI, Maciej et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 1, pp 205-214, issn 0022-2623, 10 p.Article

Interaction of arylpiperazine ligands with the hydrophobic part of the 5-HT1A receptor binding siteZLATOVIE, Mario V; SUKALOVIE, Vladimir V; SCHNEIDER, Christoph et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 9, pp 2994-3001, issn 0968-0896, 8 p.Article

Synthesis and biological evaluation of a novel structural type of serotonin 5-HT3 receptor antagonistsRAMACHANDRAN VENKATESHA PERUMAL; MAHESH, Radhakrishnan.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 10, pp 2769-2772, issn 0960-894X, 4 p.Article

Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2 -a]pyrazines as potent and selective 5-HT2C receptor agonistsRICHTER, Hans G. F; ADAMS, D. R; KNIGHT, A. R et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 5, pp 1207-1211, issn 0960-894X, 5 p.Article

Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptorsSIKAZWE, Donald; BONDAREV, Mikhail L; DUKAT, Malgorzata et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 17, pp 5217-5225, issn 0022-2623, 9 p.Article

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