Semi-mechanistic pharmacodynamic modelling of gene expression and silencing processesBERRAONDO, Pedro; GONZALEZ-ASEGUINOLAZA, Gloria; TROCONIZ, Iñaki F et al.European journal of pharmaceutical sciences. 2009, Vol 37, Num 3-4, pp 418-426, issn 0928-0987, 9 p.Article

Population Pharmacokinetic/Pharmacodynamic Model for the Sedative Effects of Flibanserin in Healthy VolunteersTROCONIZ, Iñaki F; BOLAND, Katja; STAAB, Alexander et al.Pharmaceutical research. 2012, Vol 29, Num 6, pp 1518-1529, issn 0724-8741, 12 p.Article

Population pharmacokinetic/pharmacodynamic modelling of the analgesic effects of tramadol in pediatricsGARRIDO, Maria J; HABRE, Walid; ROMBOUT, Ferdinand et al.Pharmaceutical research. 2006, Vol 23, Num 9, pp 2014-2023, issn 0724-8741, 10 p.Article

Modelling the anti-migraine effects of BIBN 4096 BS : A new calcitonin gene-related peptide receptor antagonistTROCONIZ, Inaki F; WOLTERS, Jan-Markus; TILLMANN, Christiane et al.Clinical pharmacokinetics. 2006, Vol 45, Num 7, pp 715-728, issn 0312-5963, 14 p.Article

Tadalafil population pharmacokinetics in patients with erectile dysfunctionTROCONIZ, Inaki F; TILLMANN, Christiane; STAAB, Alexander et al.European journal of clinical pharmacology. 2007, Vol 63, Num 6, pp 583-590, issn 0031-6970, 8 p.Article

Population pharmacokinetic modelling of BIBN 4096 BS, the first compound of the new class of calcitonin gene-related peptide receptor antagonistsTROCONIZ, Inaki F; WOLTERS, Jan-Markus; SCHAEFER, Hans Guenter et al.European journal of pharmaceutical sciences. 2004, Vol 22, Num 4, pp 287-295, issn 0928-0987, 9 p.Article

Comparison of different semi-mechanistic models for chemotherapy-related neutropenia: application to BI 2536 a Plk-1 inhibitorSOTO, Elena; STAAB, Alexander; DOEGE, Christiane et al.Cancer chemotherapy and pharmacology. 2011, Vol 68, Num 6, pp 1517-1527, issn 0344-5704, 11 p.Article

Application of different methods to formulate PEG-liposomes of oxaliplatin: Evaluation in vitro and in vivoZALBA, Sara; NAVARRO, Iñigo; TROCONIZ, Iñaki F et al.European journal of pharmaceutics and biopharmaceutics. 2012, Vol 81, Num 2, pp 273-280, issn 0939-6411, 8 p.Article

Obesity Does Not Influence the Onset and Offset of Sevoflurane Effect as Measured by the Hysteresis Between Sevoflurane Concentration and Bispectral IndexCORTINEZ, Luis I; GAMBUS, Pedro; TROCONIZ, Iñaki F et al.Anesthesia and analgesia. 2011, Vol 113, Num 1, pp 70-76, issn 0003-2999, 7 p.Article

Gene Therapy: A Pharmacokinetic/Pharmacodynamic Modelling OverviewPARRA-GUILLEN, Zinnia P; GONZALEZ-ASEGUINOLAZA, Gloria; BERRAONDO, Pedro et al.Pharmaceutical research. 2010, Vol 27, Num 8, pp 1487-1497, issn 0724-8741, 11 p.Article

The Influence of Age on the Dynamic Relationship Between End-Tidal Sevoflurane Concentrations and Bispectral IndexCORTINEZ, Luis I; TROCONIZ, Inaki F; FUENTES, Ricardo et al.Anesthesia and analgesia. 2008, Vol 107, Num 5, pp 1566-1572, issn 0003-2999, 7 p.Article

Effects of the direct thrombin inhibitor dabigatran on ex vivo coagulation time in orthopaedic surgery patients : a population model analysisLIESENFELD, Karl-Heinz; SCHÄFER, Hans G; TROCONIZ, Inaki F et al.British journal of clinical pharmacology. 2006, Vol 62, Num 5, pp 527-537, issn 0306-5251, 11 p.Article

Dealing with time-dependent pharmacokinetics during the early clinical development of a new leukotriene B₄ synthesis inhibitorTROCONIZ, Inaki F; ZSOLT, Ilonka; GARRIDO, Maria J et al.Pharmaceutical research. 2006, Vol 23, Num 7, pp 1533-1542, issn 0724-8741, 10 p.Article

Intrahepatic injection of recombinant adeno-associated virus serotype 2 overcomes gender-related differences in liver transductionBERRAONDO, Pedro; CRETTAZ, Julien; OCHOA, Laura et al.Human gene therapy. 2006, Vol 17, Num 6, pp 601-610, issn 1043-0342, 10 p.Article

Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-β kinase antagonist, in miceBUENO, Lorea; DE ALWIS, Dinesh P; PITOU, Celine et al.European journal of cancer (1990). 2008, Vol 44, Num 1, pp 142-150, issn 0959-8049, 9 p.Article

Phase I dose-finding study and a pharmacokinetic/pharmacodynamic analysis of the neutropenic response of intravenous diflomotecan in patients with advanced malignant tumoursTROCONIZ, Inaki F; GARRIDO, Maria J; SEGURA, Cristina et al.Cancer chemotherapy and pharmacology. 2006, Vol 57, Num 6, pp 727-735, issn 0344-5704, 9 p.Article

Pharmacokinetic-pharmacodynamic modeling of the influence of chronic phenytoin therapy on the rocuronium bromide response in patients undergoing brain surgeryFERNANDEZ-CANDIL, Juan; GAMBUS, Pedro L; TROCONIZ, Inaki F et al.European journal of clinical pharmacology. 2008, Vol 64, Num 8, pp 795-806, issn 0031-6970, 12 p.Article

A Semi-physiological-Based Pharmacokinetic/Pharmacodynamic Model to Describe the Effects of Topotecan on B-Lymphocyte Lineage CellsVELEZ DE MENDIZABAL, Nieves; MARTINEZ-FORERO, Iván; GARRIDO, María J et al.Pharmaceutical research. 2010, Vol 27, Num 3, pp 431-441, issn 0724-8741, 11 p.Article

Semi-mechanistic population pharmacokinetic/pharmacodynamic model for neutropenia following therapy with the Plk-1 inhibitor BI 2536 and its application in clinical developmentSOTO, Elena; STAAB, Alexander; TILLMANN, Christiane et al.Cancer chemotherapy and pharmacology. 2010, Vol 66, Num 4, pp 785-795, issn 0344-5704, 11 p.Article

Biopharmaceutic and pharmacodynamic modeling of the in vitro antiproliferative effect of new controlled delivery systems of cisplatinMORENO, Daniel; ZALBA, Sara; COLOM, Helena et al.European journal of pharmaceutical sciences. 2009, Vol 37, Num 3-4, pp 341-350, issn 0928-0987, 10 p.Article

Population Pharmacokinetics of Meropenem in Critically ill Patients Undergoing Continuous Renal Replacement TherapyISLA, Arantxazu; RODRIGUEZ-GASON, Alicia; TROCONIZ, Inaki F et al.Clinical pharmacokinetics. 2008, Vol 47, Num 3, pp 173-180, issn 0312-5963, 8 p.Article

Population pharmacokinetics of prophylactic cefoxitin in patients undergoing colorectal surgeryISLA, Arantxazu; TROCONIZ, Iñaki F; DE TEJADA, Ignacio López et al.European journal of clinical pharmacology. 2012, Vol 68, Num 5, pp 735-745, issn 0031-6970, 11 p.Article

Modelling the genesis and treatment of cancer: The potential role of physiologically based pharmacodynamicsSTEIMER, Jean-Louis; DAHL, Svein G; FRIBERG, Lena E et al.European journal of cancer (1990). 2010, Vol 46, Num 1, pp 21-32, issn 0959-8049, 12 p.Article