The effects of a TRPV1 antagonist, SB-705498, in the treatment of seasonal allergic rhinitisBAREILLE, Philippe; MURDOCH, Robert D; DENYER, Jane et al.International journal of clinical pharmacology and therapeutics. 2013, Vol 51, Num 7, pp 576-584, issn 0946-1965, 9 p.Article

TRPV1 antagonistic analgesic effect: A randomized study of AZD1386 in pain after third molar extractionQUIDING, Hans; JONZON, Bror; SVENSSON, Ola et al.Pain (Amsterdam). 2013, Vol 154, Num 6, pp 808-812, issn 0304-3959, 5 p.Article

Potent and orally efficacious benzothiazole amides as TRPV1 antagonistsBESIDSKI, Yevgeni; BROWN, William; JONES, Paul et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 19, pp 6205-6211, issn 0960-894X, 7 p.Article

Synthesis and biological evaluation of 5-substituted and 4,5-disubstituted-2-arylamino oxazole TRPV1 antagonistsPERNER, Richard J; KOENIG, John R; TURNER, Teresa M et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 13, pp 4821-4829, issn 0968-0896, 9 p.Article

2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure―activity relationships in the B and C-regionsWEI SUN; KELIANG LIU; PEARCE, Larry V et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 3, pp 1310-1318, issn 0968-0896, 9 p.Article

Receptor activity and conformational analysis of 5'-halogenated resiniferatoxin analogs as TRPV1 ligandsKWANG SU LIM; DONG WOOK KANG; YONG SOO KIM et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 1, pp 299-302, issn 0960-894X, 4 p.Article

Halogenation of 4-hydroxy/amino-3-methoxyphenyl acetamide TRPV1 agonists showed enhanced antagonism to capsaicinDONG WOOK KANG; YONG SOO KIM; KWANG SU LIM et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 22, pp 8092-8105, issn 0968-0896, 14 p.Article

Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolitesHODGETTS, Kevin J; BLUM, Charles A; BOYCE, Susan et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 15, pp 4359-4363, issn 0960-894X, 5 p.Article

Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonistsLEE, Jeewoo; KANG, Sang-Uk; MIN, Kyung-Hoon et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 18, pp 4136-4142, issn 0960-894X, 7 p.Article

Identification of potent, soluble, and orally active TRPV1 antagonistsRATCLIFFE, Paul; MACLEAN, John; MCARTHUR, Duncan et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 8, pp 2559-2563, issn 0960-894X, 5 p.Article

An investigation of the safety and pharmacokinetics of the novel TRPV1 antagonist XEN-D0501 in healthy subjectsROUND, Patrick; PRIESTLEY, Anthony; ROBINSON, Jan et al.British journal of clinical pharmacology. 2011, Vol 72, Num 6, pp 921-931, issn 0306-5251, 11 p.Article

LASSBio-881: an N-acylhydrazone transient receptor potential vanilloid subfamily type 1 antagonist orally effective against the hypernociception induced by capsaicin or partial sciatic ligationTRIBUTINO, J. L. M; SANTOS, M. L. H; MIRANDA, A. L. P et al.British journal of pharmacology. 2010, Vol 159, Num 8, pp 1716-1723, issn 0007-1188, 8 p.Article

Structure―activity relationships and molecular modeling of the N-(3-pivaloyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl] thiourea template for TRPV1 antagonismBHONDWE, Rahul S; DONG WOOK KANG; BLUMBERG, Peter M et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 11, pp 3656-3660, issn 0960-894X, 5 p.Article

Structure-activity studies of a novel series of isoxazole-3-carboxamide derivatives as TRPV1 antagonistsPALIN, Ronald; ABERNETHY, Lynn; EVERETT, Katy et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 3, pp 892-898, issn 0960-894X, 7 p.Article

Discovery of potent, soluble and orally active TRPV1 antagonists. Structure-activity relationships of a series of isoxazolesRATCLIFFE, Paul; ABERNETHY, Lynn; FEILDEN, Helen et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 15, pp 4652-4657, issn 0960-894X, 6 p.Article

N-tetrahydroquinolinyl, N-quinolinyl and N-isoquinolinyl biaryl carboxamides as antagonists of TRPV1WESTAWAY, Susan M; CHUNG, Ying-Kit; WINBORN, Kim Y et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 17, pp 4533-4536, issn 0960-894X, 4 p.Article

Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl ]- thiourea analogues as TRPV1 antagonistsLEE, Jeewoo; JIN, Mi-Kyoung; KIM, Sung-Eun et al.Bioorganic & medicinal chemistry letters (Print). 2005, Vol 15, Num 18, pp 4143-4150, issn 0960-894X, 8 p.Article

Structure-activity relationship (SAR) investigations of substituted imidazole analogs as TRPV1 antagonistsGORE, Vijay K; MA, Vu V; TAMIR, Rami et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 21, pp 5825-5830, issn 0960-894X, 6 p.Article

Effect of paclitaxel on transient receptor potential vanilloid 1 in rat dorsal root ganglionHARA, Tomomi; CHIBA, Terumasa; ABE, Kenji et al.Pain (Amsterdam). 2013, Vol 154, Num 6, pp 882-889, issn 0304-3959, 8 p.Article

TRPV1 inhibition does not prevent cold dry air-elicited symptoms in non-allergic rhinitisMURDOCH, Robert D; BAREILLE, Philippe; DENYER, Jane et al.International journal of clinical pharmacology and therapeutics. 2014, Vol 52, Num 4, pp 267-276, issn 0946-1965, 10 p.Article

Chroman and tetrahydroquinoline ureas as potent TRPV1 antagonistsSCHMIDT, Robert G; BAYBURT, Erol K; MARSH, Kennan C et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 5, pp 1338-1341, issn 0960-894X, 4 p.Article

Conformationally constrained analogues of N'-(4-tert-butylbenzyl)-N-(4-methylsulfonylaminobenzyl)thiourea as TRPV1 antagonistsLIM, Ju-Ok; JIN, Mi-Kyoung; RYU, Hyungchul et al.European journal of medicinal chemistry. 2009, Vol 44, Num 1, pp 322-331, issn 0223-5234, 10 p.Article

α-Substituted N-(4 -tert-butylbenzyl ) -N'-[4 -(methylsulfonylamino )-benzyl]thiourea analogues as potent and stereospecific TRPV1 antagonistsCHUNG, Jae-Uk; SU YEON KIM; CHOI, Sun et al.Bioorganic & medicinal chemistry. 2007, Vol 15, Num 18, pp 6043-6053, issn 0968-0896, 11 p.Article

Structure-activity studies of a novel series of 5,6-fused heteroaromatic ureas as TRPV1 antagonistsDRIZIN, Irene; GOMTSYAN, Arthur; BROWN, Brian S et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 14, pp 4740-4749, issn 0968-0896, 10 p.Article