The role of nucleotide excision repair and loss of p53 in mutagenesis and carcinogenesisVAN STEEG, Harry.Toxicology letters. 2001, Vol 120, Num 1-3, pp 209-219, issn 0378-4274Conference Paper

Aging and genome maintenance: Lessons from the mouse? : AgingHASTY, Paul; CAMPISI, Judith; HOELJMAKERS, Jan et al.Science (Washington, D.C.). 2003, Vol 299, Num 5611, pp 1355-1359, issn 0036-8075, 5 p.Article

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approachHERNANDEZ, Lya G; VAN STEEG, Harry; LUIJTEN, Mirjam et al.Mutation research. Reviews in mutation research. 2009, Vol 682, Num 2-3, pp 94-109, issn 1383-5742, 16 p.Article

TransgenicsHEDDLE, John A; GLICKMAN, Barry W; NOHMI, Takehiko et al.Environmental and molecular mutagenesis (Print). 1999, Vol 34, Num 2-3, issn 0893-6692, 160 p.Serial Issue

Molecular misreading: the frequency of dinucleotide deletions in neuronal mRNAs for β-amyloid precursor protein and ubiquitin BGEREZ, Lisya; DE HAAN, Annett; HOL, Elly M et al.Neurobiology of aging. 2005, Vol 26, Num 2, pp 145-155, issn 0197-4580, 11 p.Article

Age-related mutation accumulation at a lacZ reporter locus in normal and tumor tissues of Trp53-deficient miceGIESE, Heidi; SNYDER, Wendy K; VAN OOSTROM, Conny et al.Mutation research. Genetic toxicology and environmental mutagenesis. 2002, Vol 514, Num 1-2, pp 153-163, issn 1383-5718Article

Use of the local lymph node assay in assessment of immune functionVAN DEN BERG, Femke A; BAKEN, Kirsten A; VERMEULEN, Jolanda P et al.Toxicology (Amsterdam). 2005, Vol 211, Num 1-2, pp 107-114, issn 0300-483X, 8 p.Article

Suppression of UV carcinogenesis by difluoromethylornithine in nucleotide excision repair-deficient Xpa knockout miceREBEL, Heggert; VAN STEEG, Harry; BEEMS, Rudolf B et al.Cancer research (Baltimore). 2002, Vol 62, Num 5, pp 1338-1342, issn 0008-5472Article

Treatment of lacZ plasmid-based transgenic mice with benzo[a]pyrene : Measurement of DNA adduct levels, mutant frequencies, and mutant spectraBOERRIGTER, M. E. T. I.Environmental and molecular mutagenesis (Print). 1999, Vol 34, Num 2-3, pp 140-147, issn 0893-6692Article

Kinetics of induction of DNA damage and lacZ gene mutations in stomach mucosa of mice treated with β-propiolactone and N-methyl-N'-nitro-n-nitrosoguanidine, using single-cell gel electrophoresis and MutaMouse modelsBRAULT, D; RENAULT, D; TOMBOLAN, F et al.Environmental and molecular mutagenesis (Print). 1999, Vol 34, Num 2-3, pp 182-189, issn 0893-6692Article

DNA repair-deficient Xpalp53 knockout mice are sensitive to the non-genotoxic carcinogen cyclosporine A : escape of initiated cells from immunosurveillance?VAN KESTEREN, Petra C. E; BEEMS, Rudolf B; LUIJTEN, Mirjam et al.Carcinogenesis (New York. Print). 2009, Vol 30, Num 3, pp 538-543, issn 0143-3334, 6 p.Article

Characterization of new transgenic Big Blue® mouse and rat primary fibroblast cell strains for use in molecular toxicology studiesEREXSON, G. L; WATSON, D. E; TINDALL, K. R et al.Environmental and molecular mutagenesis (Print). 1999, Vol 34, Num 2-3, pp 90-96, issn 0893-6692Article

Is Muta™mouse insensitive to clastogens?LYNCH, Anthony M; MAHABIR, Anuska G; BRADFORD, Andrea et al.Mutation research. Genetic toxicology and environmental mutagenesis. 2008, Vol 652, Num 2, pp 145-150, issn 1383-5718, 6 p.Article

Efficient detection of deletions induced by a single treatment of mitomycin C in transgenic mouse gpt delta using the Spi^- selectionOKADA, N; MASUMURA, K.-I; NOHMI, T et al.Environmental and molecular mutagenesis (Print). 1999, Vol 34, Num 2-3, pp 106-111, issn 0893-6692Article

Mutational spectrum of dimethylnitrosamine in the liver of 3- and 6-week-old lacI transgenic miceDE BOER, J. G; MIRSALIS, J. C; GLICKMAN, B. W et al.Environmental and molecular mutagenesis (Print). 1999, Vol 34, Num 2-3, pp 80-83, issn 0893-6692Article

New methods for assessing male germ line mutations in humans and genetic risks in their offspringVERHOFSTAD, Nicole; LINSCHOOTEN, Joost O; VAN BENTHEM, Jan et al.Mutagenesis. 2008, Vol 23, Num 4, pp 241-247, issn 0267-8357, 7 p.Article

Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damageWIJNHOVEN, Susan W. P; SPEKSNIJDER, Ewoud N; VAN STEEG, Harry et al.Cancer research (Baltimore). 2007, Vol 67, Num 10, pp 4648-4656, issn 0008-5472, 9 p.Article

2-AAF-induced tumor development in nucleotide excision repair-deficient mice is associated with a defect in global genome repair but not with transcription coupled repairHOOGERVORST, Esther M; VAN OOSTROM, Conny Th. M; BEEMS, Rudolf B et al.DNA repair. 2005, Vol 4, Num 1, pp 3-9, issn 1568-7864, 7 p.Article

p53 Heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa miceHOOGERVORST, Esther M; VAN OOSTROM, Conny Th. M; BEEMS, Rudolf B et al.Cancer research (Baltimore). 2004, Vol 64, Num 15, pp 5118-5126, issn 0008-5472, 9 p.Article

The relationship between benzo[a]pyrene-induced mutagenesis and carcinogenesis in repair-deficient cockayne syndrome group B miceWIJNHOVEN, Susan W. P; KOOL, Hanneke J. M; VAN OOSTROM, Conny T. M et al.Cancer research (Baltimore). 2000, Vol 60, Num 20, pp 5681-5687, issn 0008-5472Article

Partial hepatectomy strongly increased the mutagenicity of N-ethyl-N-nitrosourea in MutaMouse liverHARA, T; SUI, H; KAWAKAMI, K et al.Environmental and molecular mutagenesis (Print). 1999, Vol 34, Num 2-3, pp 121-123, issn 0893-6692Article

Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse modelsJONKER, Martijs J; BRUNING, Oskar; LUIJTEN, Mirjam et al.Carcinogenesis (New York. Print). 2009, Vol 30, Num 10, pp 1805-1812, issn 0143-3334, 8 p.Article

Combined oral benzo[a]pyrene and inhalatory ozone exposure have no effect on lung tumor development in DNA repair-deficient Xpa miceHOOGERVORST, Esther M; DE VRIES, Annemieke; VAN SCHOOTEN, Frederik-Jan et al.Carcinogenesis (New York. Print). 2003, Vol 24, Num 3, pp 613-619, issn 0143-3334, 7 p.Article

Xpa and Xpa/p53^+/- knockout mice: Overview of available dataVAN KREIJL, Coen F; MCANULTY, Peter A; BEEMS, Rudolf B et al.Toxicologic pathology. 2001, Vol 29, pp 117-127, issn 0192-6233, SUP-DEFECTUEUXArticle

The cll locus in the MutaMouse systemSWIGER, R. R; COSENTINO, L; SHIMA, N et al.Environmental and molecular mutagenesis (Print). 1999, Vol 34, Num 2-3, pp 201-207, issn 0893-6692Article