EFFECTS OF PRETREATMENT WITH PHENOBARBITONE AND PHENYTOIN ON THE PHARMACOKINETICS AND TOXICITY OF MISONIDAZOLE IN MICEWORKMAN P.1979; BRIT. J. CANCER; GBR; DA. 1979; VOL. 40; NO 3; PP. 335-353; BIBL. 2 P.Article

INHIBITION OF HUMAN PROSTATIC TUMOUR ACID PHOSPHATASE BY N,N-P-DI-2-CHLOROETHYLAMINOPHENOL, N,N-P-DI-2-CHLOROETHYLAMINOPHENYL PHOSPHATE AND OTHER DIFUNCTIONAL NITROGEN MUSTARDS.WORKMAN P.1978; CHEMICO-BIOL. INTERACTIONS; NETHERL.; DA. 1978; VOL. 20; NO 1; PP. 103-112; BIBL. 1 P. 1/2Article

DRUG INTERACTIONS WITH MISONIDAZOLE: EFFECTS OF DEXAMETHASONE AND ITS DERIVATIVES ON THE PHARMACOKINETICS AND TOXICITY OF MISONIDAZOLE IN MICEWORKMAN P.1980; BIOCHEM. PHARMACOL.; ISSN 0006-2952; GBR; DA. 1980; VOL. 29; NO 20; PP. 2769-2776; BIBL. 32 REF.Article

DOSE-DEPENDENCE AND RELATED STUDIES ON THE PHARMACOKINETICS OF MISONIDAZOLE AND DESMETHYLMISONIDAZOLE IN MICEWORKMAN P.1980; CANCER CHEMOTHER. PHARMACOL.; ISSN 0344-5704; DEU; DA. 1980; VOL. 5; NO 1; PP. 27-37; BIBL. 22 REF.Article

ANALYSIS OF THE BASIC 5-NITROIMIDAZOLE NIMORAZOLE IN BLOOD BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY AND ITS APPLICATION TO PHARMACOKINETIC STUDIES IN INDIVIDUAL MICEWORKMAN P.1979; J. CHROMATOGR.; NLD; DA. 1979; VOL. 163; NO 4; PP. 396-402; BIBL. 11 REF.Article

EFFECTS OF THE XANTHINE OXIDASE INHIBITOR ALLOPURINOL ON THE RENAL CLEARANCE OF NITROIMIDAZOLESWORKMAN P; WHITE RAS.1982; BIOCHEMICAL PHARMACOLOGY; ISSN 0006-2952; GBR; DA. 1982; VOL. 31; NO 19; PP. 3041-3046; BIBL. 31 REF.Article

PHARMACOKINETIC AND TUMOUR-PENETRATION PROPERTIES OF THE HYPOXIC CELL RADIOSENSITIZER DESMETHYLMISONIDAZOLE (RO 05-9963) IN DOGSWHITE RAS; WORKMAN P.1980; BRIT. J. CANCER; GBR; DA. 1980; VOL. 41; NO 2; PP. 268-276; BIBL. 17 REF.Article

Emerging from a crisis in anticancer drug discovery? Screening versus design : confessions of an optimistic fence-sitterWORKMAN, P.Annals of oncology. 1992, Vol 3, Num 9, pp 699-705, issn 0923-7534Article

A NEW HIGH-GLUCURONIDASE MOUSE TUMOR CURABLE BY ANILINE MUSTARD THERAPY.DOUBLE JA; WORKMAN P.1977; CANCER TREATM. REP.; U.S.A.; DA. 1977; VOL. 61; NO 5; PP. 909-911; BIBL. 11 REF.Article

Signal transduction inhibitors as novel anticancer drugs: where are we?WORKMAN, P.Annals of oncology. 1992, Vol 3, Num 7, pp 531-537, issn 0923-7534Article

TCNU: a ray of hope for designer nitrosoureas?WORKMAN, P.European journal of cancer & clinical oncology. 1987, Vol 23, Num 12, pp 1823-1828, issn 0277-5379Article

DRUG LATENTIATION IN CANCER CHEMOTHERAPYWORKMAN P; DOUBLE JA.1978; BIOMEDICINE; FRA; DA. 1978; VOL. 28; NO 5; PP. 255-262; ABS. FRE; BIBL. 118 REF.Article

EFFECT OF MISONIDAZOLE OR METRONIDAZOLE PRETREATMENT ON THE RESPONSE OF THE RIF-1 MOUSE SARCOMA TO MELPHALAN, CYCLOPHOSPHAMIDE, CHLORAMBUCIL AND CCNUTWENTYMAN P; WORKMAN P.1982; BR. J. CANCER; ISSN 0007-0920; GBR; DA. 1982; VOL. 45; NO 3; PP. 447-455; BIBL. 16 REF.Article

AN ASSAY FOR PLASMA MEMBRANE PHOSPHATE ACTIVITY IN POPULATIONS OF INDIVIDUAL CELLSWATSON JV; WORKMAN P; CHAMBERS SH et al.1979; BIOCHEM. PHARMACOL.; GBR; DA. 1979; VOL. 28; NO 6; PP. 821-827; BIBL. 25 REF.Article

DIFFERENT ESTERASE ACTIVITIES OF EXPONENTIAL AND PLATEAU PHASES OF EMT6 CELLS MONITORED BY FLOW CYTOFLUORIMETRY.WATSON JV; WORKMAN P; CHAMBERS SH et al.1978; BRIT. J. CANCER; GBR; DA. 1978; VOL. 37; NO 3; PP. 397-402; BIBL. 16 REF.Article

RESPONSE OF A HIGH-GLUCURONIDASE HUMAN TUMOUR XENOGRAFT TO ANILINE MUSTARDWARENIUS HM; WORKMAN P; BLECHAN NM et al.1982; BR. J. CANCER; ISSN 0007-0920; GBR; DA. 1982; VOL. 45; NO 1; PP. 27-34; BIBL. 18 REF.Article

PHENYTOIN SHORTENS THE HALF-LIFE OF THE HYPOXIC CELL RADIOSENSITIZER MISONIDAZOLE IN MAN: IMPLICATIONS FOR POSSIBLE REDUCED TOXICITYWORKMAN P; BLEEHEN NM; WILTSHIRE CR et al.1980; BRIT. J. CANCER; GBR; DA. 1980; VOL. 41; NO 2; PP. 302-304; BIBL. 13 REF.Article

ENZYME ACTIVATED ANTI-TUMOUR AGENTS. II. THE ROLE OF ALKALINE PHOSPHATASE IN THE RELEASE OF P-HYDROXYANILINE MUSTARD FROM ITS PHOSPHATE CONJUGATE IN CELLS IN CULTURED = LES AGENTS ANTITUMORAUX ACTIVES PAR DES ENZYMES. II. LE ROLE DE LA PHOSPHATASE ALCALINE DANS LA LIBERATION DE LA MOUTARDE DE LA P-HYDROXYANILINE DE SON CONJUGUE PHOSPHATE DANS LES CELLULES EN CULTUREWORKMAN P; BALL CR; DOUBLE JA et al.1976; BIOCHEM. PHARMACOL.; G.B.; DA. 1976; VOL. 25; NO 10; PP. 1139-1144; BIBL. 46 REF.Article

Cell-signaling targets for antitumour drug developmentBRUNTON, V. G; WORKMAN, P.Cancer chemotherapy and pharmacology. 1993, Vol 32, Num 1, pp 1-19, issn 0344-5704Article

Pharmacokinetic contribution to the improved therapeutic selectivity of a novel bromoethylamino prodrug (RB 6145) of the mixed-function hypoxic cell sensitizer/cytotoxin α-(1-aziridinomethyl)-2-nitro-1H-imidazole-1-ethanol (RSU 1069)BINGER, M; WORKMAN, P.Cancer chemotherapy and pharmacology. 1991, Vol 29, Num 1, pp 37-47, issn 0344-5704Article

EFFECTS OF LOCAL HYPERTHERMIA ON THE PHARMACOKINETICS OF MISONIDAZOLE IN THE ANAESTHETIZED MOUSEHONESS DJ; WORKMAN P; MORGAN JE et al.1980; BRIT. J. CANCER; GBR; DA. 1980; VOL. 41; NO 4; PP. 529-540; BIBL. 31 REF.Article

Challenges of PK/PD measurements in modern drug developmentWORKMAN, P.European journal of cancer (1990). 2002, Vol 38, Num 16, pp 2189-2193, issn 0959-8049Article

Signalling targets for the development of cancer drugsPOWIS, G; WORKMAN, P.Anti-cancer drug design. 1994, Vol 9, Num 4, pp 263-277, issn 0266-9536Article

Unusually marked hypoxic sensitization to indoloquinone EO9 and mitomycin C in a human colon-tumour cell line that lacks DT-diaphorase activityPLUMB, J. A; WORKMAN, P.International journal of cancer. 1994, Vol 56, Num 1, pp 134-139, issn 0020-7136Article

Normalisation of anti-cancer drug dosage using body weight and surface area : is it worthwhile ? A review of theoretical and practical considerationsREILLY, J. J; WORKMAN, P.Cancer chemotherapy and pharmacology. 1993, Vol 32, Num 6, pp 411-418, issn 0344-5704Article