'Inverted' analogs of the antibiotic gramicidin S with an improved biological profileKAPOERCHAN, Varsha V; KNIJNENBURG, Annemiek D; DER MAREL, Gijs A. Van et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 20, pp 6059-6062, issn 0968-0896, 4 p.Article

2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure―activity relationships in the B and C-regionsWEI SUN; KELIANG LIU; PEARCE, Larry V et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 3, pp 1310-1318, issn 0968-0896, 9 p.Article

A review on coumarins as acetylcholinesterase inhibitors for Alzheimer's diseaseANAND, Preet; SINGH, Baldev; SINGH, Nirmal et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 3, pp 1175-1180, issn 0968-0896, 6 p.Article

ANN multiplexing model of drugs effect on macrophages; theoretical and flow cytometry study on the cytotoxicity of the anti-microbial drug G1 in spleenTENORIO-BORROTO, Esvieta; PENUELAS RIVAS, Claudia G; VASQUEZ CHAGOYAN, Juan C et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 20, pp 6181-6194, issn 0968-0896, 14 p.Article

Advancements in Z-DNA: Development of Inducers and Stabilizers for B to Z TransitionYANG, L; WANG, S; TIAN, T et al.Current medicinal chemistry. 2012, Vol 19, Num 4, pp 557-568, issn 0929-8673, 12 p.Article

Alstiphyllanines I―O, ajmaline type alkaloids from Alstonia macrophylla showing vasorelaxant activityARAI, Hiroko; ZAIMA, Kazumasa; MITSUTA, Erika et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 11, pp 3454-3459, issn 0968-0896, 6 p.Article

Aminothienopyridazine inhibitors of tau aggregation: Evaluation of structure―activity relationship leads to selection of candidates with desirable in vivo propertiesBALLATORE, Carlo; CROWE, Alex; SMITH, Amos B et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 14, pp 4451-4461, issn 0968-0896, 11 p.Article

Analysis of the structural and mechanistic factors in antioxidants that preserve mitochondrial function and confer cytoprotectionARCE, Pablo M; GOLDSCHMIDT, Ruth; KHDOUR, Omar M et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 17, pp 5188-5201, issn 0968-0896, 14 p.Article

Antitubercular nitrofuran isoxazolines with improved pharmacokinetic propertiesRAKESH; BRUHN, David; MCNEIL, Michael R et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 20, pp 6063-6072, issn 0968-0896, 10 p.Article

Approaches Targeting K_v10.1 Open a Novel Window for Cancer Diagnosis and Therapy : Ion Channels and CancersPARDO, L. A; GOMEZ-VARELA, D; MAJOR, F et al.Current medicinal chemistry. 2012, Vol 19, Num 5, pp 675-682, issn 0929-8673, 8 p.Article

Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatasesLOK HANG MAK; KNOTTY, Jessica; SCOTT, Katherine A et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 14, pp 4371-4376, issn 0968-0896, 6 p.Article

Attenuating the size and molecular carrier capabilities of polyacrylate nanoparticles by a hydrophobic fluorine effectLABRUERE, Raphael; TUROS, Edward.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 16, pp 5042-5045, issn 0968-0896, 4 p.Article

Bidirectional fluorescence properties of pyrene-based peroxisome proliferator-activated receptor (PPAR) α/δ dual agonistBAN, Shintaro; OYAMA, Takuji; KASUGA, Jun-Ichi et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 11, pp 3460-3464, issn 0968-0896, 5 p.Article

BioProfile―Extract knowledge from corporate databases to assess cross-reactivities of compounds : Chemoinformatics in Drug DiscoveryBECK, Bernd.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 18, pp 5428-5435, issn 0968-0896, 8 p.Article

Bisubstrate analog inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New lead exhibits a distinct binding modeGENBIN SHI; SHAW, Gary; YUE LI et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 14, pp 4303-4309, issn 0968-0896, 7 p.Article

Bivalent molecular probes for dopamine D₂-like receptorsHUBER, Daniela; LÖBER, Stefan; HÜBNER, Harald et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 1, pp 455-466, issn 0968-0896, 12 p.Article

C-C bond formation at C-2 of a quinoline ring: Synthesis of 2-(1H-indol-3-yl) quinoline-3-carbonitrile derivatives as a new class of PDE4 inhibitorsSHIVA KUMAR, K; KIRAN KUMAR, S; PAL, Manojit et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 7, pp 2199-2207, issn 0968-0896, 9 p.Article

COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substratesFAGAN, Vincent; BONHAM, Sarah; CARTY, Michael P et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 10, pp 3223-3232, issn 0968-0896, 10 p.Article

Cellular uptake of covalent conjugates of oligonucleotide with membrane-modifying peptide, peptaibolWADA, Shun-Ichi; HITORA, Yasunari; YOKOE, Saori et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 10, pp 3219-3222, issn 0968-0896, 4 p.Article

ChemoImmunoModulation: Immune Regulation by the Antineoplastic Chemotherapeutic Agents : Modulation of the Immune System by Ionizing Irradiation and Chemotherapeutic Agents - Contribution of Immune Activation and Blocking of Immune Suppression to Cancer Therapy SuccessSHURIN, M. R; NAIDITCH, H; GUTKIN, D. W et al.Current medicinal chemistry. 2012, Vol 19, Num 12, pp 1792-1803, issn 0929-8673, 12 p.Article

Chemoinformatics: A view of the field and current trends in method development : Chemoinformatics in Drug DiscoveryVOGT, Martin; BAJORATH, Jürgen.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 18, pp 5317-5323, issn 0968-0896, 7 p.Article

Click-based synthesis of triazolobithiazole ΔF508-CFTR correctors for cystic fibrosisDONALD, Michael B; RODRIGUEZ, Kevin X; SHAY, Hannah et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 17, pp 5247-5253, issn 0968-0896, 7 p.Article

Curcumin is an inhibitor of calcium/calmodulin dependent protein kinase IIMAYADEVI, M; SHERIN, D. R; KEERTHI, V. S et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 20, pp 6040-6047, issn 0968-0896, 8 p.Article

C―N bond formation under Cu-catalysis: Synthesis and in vitro evaluation of N-aryl substituted thieno[2,3-d]pyrimidin-4(3H)-ones against chorismate mutaseADEPU, Raju; KUMAR, K. Shiva; SANDRA, Sandhya et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 17, pp 5127-5138, issn 0968-0896, 12 p.Article

Database of bioactive ring systems with calculated properties and its use in bioisosteric design and scaffold hopping : Chemoinformatics in Drug DiscoveryERTL, Peter.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 18, pp 5436-5442, issn 0968-0896, 7 p.Article