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Results 1 to 25 of 11045

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A network-based approach to quantifying the impact of biologically active substancesHOEING, Julia; DEEHAN, Renée; PRATT, Dexter et al.Drug discovery today. 2012, Vol 17, Num 9-10, pp 413-418, issn 1359-6446, 6 p.Article

A minimalist fragment approach for the design of natural-product-like synthetic scaffoldsGENIS, Dmitry; KIRPICHENOK, Mikhail; KOMBAROV, Roman et al.Drug discovery today. 2012, Vol 17, Num 21-22, pp 1170-1174, issn 1359-6446, 5 p.Article

Amino acid―anticodon binding specificity: rationale for a new class of therapeutic agentMELZER, Marvin S.Drug discovery today. 2012, Vol 17, Num 7-8, pp 291-295, issn 1359-6446, 5 p.Article

An overview of natural polymers for oral insulin deliverySONIA, T. A; SHARMA, Chandra P.Drug discovery today. 2012, Vol 17, Num 13-14, pp 784-792, issn 1359-6446, 9 p.Article

Applications of saturation transfer difference NMR in biological systemsBHUNIA, Anirban; BHATTACHARJYA, Surajit; CHATTERJEE, Subhrangsu et al.Drug discovery today. 2012, Vol 17, Num 9-10, pp 505-513, issn 1359-6446, 9 p.Article

Auto-associative amphiphilic polysaccharides as drug delivery systemsHASSANI, Leila N; HENDRA, Frédéric; BOUCHEMAL, Kawthar et al.Drug discovery today. 2012, Vol 17, Num 11-12, pp 608-614, issn 1359-6446, 7 p.Article

Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survivalMORGAN, Paul; VAN DER GRAAF, Piet H; ARROWSMITH, John et al.Drug discovery today. 2012, Vol 17, Num 9-10, pp 419-424, issn 1359-6446, 6 p.Article

Case study: adapting in vitro blood―brain barrier models for use in early-stage drug discoveryVANDENHAUTE, Elodie; SEVIN, Emmanuel; HALLIER-VANUXEEM, Dorothée et al.Drug discovery today. 2012, Vol 17, Num 7-8, pp 285-290, issn 1359-6446, 6 p.Article

Computational models for predicting substrates or inhibitors of P-glycoproteinLEI CHEN; YOUYONG LI; HUIDONG YU et al.Drug discovery today. 2012, Vol 17, Num 7-8, pp 343-351, issn 1359-6446, 9 p.Article

Does transbilayer diffusion have a role in membrane transport of drugs?BALAZ, Stefan.Drug discovery today. 2012, Vol 17, Num 19-20, pp 1079-1087, issn 1359-6446, 9 p.Article

Effective pharmaceutical regulation needs alignment with doctorsEBBERS, Hans C; PIETERS, Toine; LEUFKENS, Hubert G et al.Drug discovery today. 2012, Vol 17, Num 3-4, pp 100-103, issn 1359-6446, 4 p.Article

Expanding the medicinally relevant chemical space with compound librariesLOPEZ-VALLEJO, Fabian; GIULIANOTTI, Marc A; HOUGHTEN, Richard A et al.Drug discovery today. 2012, Vol 17, Num 13-14, pp 718-726, issn 1359-6446, 9 p.Article

Farnesoid X receptor targeting to treat nonalcoholic steatohepatitisADORINI, Luciano; PRUZANSKI, Mark; SHAPIRO, David et al.Drug discovery today. 2012, Vol 17, Num 17-18, pp 988-997, issn 1359-6446, 10 p.Article

Foundation review: urrent therapies in ischemic stroke. Part A. Recent developments in acute stroke treatment and in stroke preventionBROUSSALIS, Erasmia; KILLER, Monika; MCCOY, Mark et al.Drug discovery today. 2012, Vol 17, Num 7-8, pp 296-309, issn 1359-6446, 14 p.Article

Function and regulation of large conductance Ca2+-activated K+ channel in vascular smooth muscle cellsHU, Xiang-Qun; LUBO ZHANG.Drug discovery today. 2012, Vol 17, Num 17-18, pp 974-987, issn 1359-6446, 14 p.Article

HSP90 inhibition: two-pronged exploitation of cancer dependenciesTRAVERS, Jon; SHARP, Swee; WORKMAN, Paul et al.Drug discovery today. 2012, Vol 17, Num 5-6, pp 242-252, issn 1359-6446, 11 p.Article

How to conduct and interpret ITC experiments accurately for cyclodextrin-guest interactionsBOUCHEMAL, Kawthar; MAZZAFERRO, Silvia.Drug discovery today. 2012, Vol 17, Num 11-12, pp 623-629, issn 1359-6446, 7 p.Article

Liposomal drug formulations in cancer therapy: 15 years along the roadSLINGERLAND, Marije; GUCHELAAR, Henk-Jan; GELDERBLOM, Hans et al.Drug discovery today. 2012, Vol 17, Num 3-4, pp 160-166, issn 1359-6446, 7 p.Article

Liver uptake of radiolabeled targeting proteins and peptides: considerations for targeting peptide conjugate designSEYED JALAL HOSSEINIMEHR; TOLMACHEV, Vladimir; ORLOVA, Anna et al.Drug discovery today. 2012, Vol 17, Num 21-22, pp 1224-1232, issn 1359-6446, 9 p.Article

Nanotechnology-based combinational drug delivery: an emerging approach for cancer therapyPARHI, Priyambada; MOHANTY, Chandana; SANJEEB KUMAR SAHOO et al.Drug discovery today. 2012, Vol 17, Num 17-18, pp 1044-1052, issn 1359-6446, 9 p.Article

Natural and synthetic α-methylenelactones and α-methylenelactams with anticancer potentialJANECKA, Anna; WYREBSKA, Anna; GACH, Katarzyna et al.Drug discovery today. 2012, Vol 17, Num 11-12, pp 561-572, issn 1359-6446, 12 p.Article

Nonprofit drugs as the salvation of the world's healthcare systems: the case of Antabuse (disulfıram)CVEK, Boris.Drug discovery today. 2012, Vol 17, Num 9-10, pp 409-412, issn 1359-6446, 4 p.Article

Physiological, pathological and potential therapeutic roles of adipokinesFAKAO-PIRES, Inês; CASTRO-CHAVES, Paulo; MIRANDA-SILVA, Daniela et al.Drug discovery today. 2012, Vol 17, Num 15-16, pp 880-889, issn 1359-6446, 10 p.Article

Retrospective clinical analysis for drug rescue: for new indications or stratified patient groupsCAVALLA, David; SINGAL, Chaim.Drug discovery today. 2012, Vol 17, Num 3-4, pp 104-109, issn 1359-6446, 6 p.Article

The potential of incretin-based therapies in type 1 diabetesSUEN, Chen S; BURN, Paul.Drug discovery today. 2012, Vol 17, Num 1-2, pp 89-95, issn 1359-6446, 7 p.Article

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