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Results 1 to 25 of 39902

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Cellular and human pharmacokinetics of brivudin, a new antiherpetic drugCREA, A. E. G; LAFRATE, E. M; EVANGELISTA, S et al.Recent research developments in drug metabolism and disposition Vol. 2 - 2004. Recent developments in drug metabolism and disposition. 2004, pp 27-37, isbn 81-7895-135-5, 11 p.Book Chapter

Human placental drug metabolism and transport: The placental perfusion model as a powerful tool for both metabolism and transportCOLLIER, Abby C; KEELAN, Jeffrey A; MITCHELL, Murray D et al.Recent research developments in drug metabolism and disposition Vol. 2 - 2004. Recent developments in drug metabolism and disposition. 2004, pp 39-54, isbn 81-7895-135-5, 16 p.Book Chapter

Effect of an epidermal growth factor receptor (EGFr) tyrosine kinase inhibitor (OSI-774) on thymidine uptake in athymic nude mice bearing human HN5 tumor xenographsPOTCHOIBA, Michael J; SMOLAREK, Teresa A; BAKER, Deborah A et al.Recent research developments in drug metabolism and disposition Vol. 2 - 2004. Recent developments in drug metabolism and disposition. 2004, pp 1-14, isbn 81-7895-135-5, 14 p.Book Chapter

A Semiphysiological Population Model for Prediction of the Pharmacokinetics of Drugs under Liver and Renal Disease ConditionsSTROUGO, Ashley; YASSEN, Ashraf; KRAUWINKEL, Walter et al.Drug metabolism and disposition. 2011, Vol 39, Num 7, pp 1278-1287, issn 0090-9556, 10 p.Article

A Single Dose Mass Balance Study of the Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Humans Using Accelerator Mass SpectrometryGRAHAM, Richard A; LUM, Bert L; MINLI XIE et al.Drug metabolism and disposition. 2011, Vol 39, Num 8, pp 1460-1467, issn 0090-9556, 8 p.Article

Absorption and Disposition of Scutellarin in Rats: A Pharmacokinetic Explanation for the High Exposure of Its Isomeric MetaboliteCHUNYING GAO; XIAOYAN CHEN; DAFANG ZHONG et al.Drug metabolism and disposition. 2011, Vol 39, Num 11, pp 2034-2044, issn 0090-9556, 11 p.Article

Absorption and Disposition of the Sphingosine 1-Phosphate Receptor Modulator Fingolimod (FTY720) in Healthy Volunteers: A Case of Xenobiotic Biotransformation Following Endogenous Metabolic PathwaysZOLLINGER, Markus; GSCHWIND, Hans-Peter; YI JIN et al.Drug metabolism and disposition. 2011, Vol 39, Num 2, pp 199-207, issn 0090-9556, 9 p.Article

Bioavailability of the Glucuronide and Sulfate Conjugates of Genistein and Daidzein in Breast Cancer Resistance Protein 1 Knockout MiceALVAREZ, Ana I; VALLEJO, Fernando; BARRERA, Borja et al.Drug metabolism and disposition. 2011, Vol 39, Num 11, pp 2008-2012, issn 0090-9556, 5 p.Article

Brain Tissue Binding of Drugs: Evaluation and Validation of Solid Supported Porcine Brain Membrane Vesicles (TRANSIL) as a Novel High-Throughput MethodLONGHI, Raffaele; CORBIOLI, Silvia; FONTANA, Stefano et al.Drug metabolism and disposition. 2011, Vol 39, Num 2, pp 312-321, issn 0090-9556, 10 p.Article

Characterization and Crystallization of Mouse Aldehyde Oxidase 3: From Mouse Liver to Escherichia coli Heterologous Protein ExpressionMAHRO, Martin; COELHO, Catarina; LEIMKÜHLER, Silke et al.Drug metabolism and disposition. 2011, Vol 39, Num 10, pp 1939-1945, issn 0090-9556, 7 p.Article

Characterization of Recombinant Human Carboxylesterases: Fluorescein Diacetate as a Probe Substrate for Human Carboxylesterase 2JIE WANG; WILLIAMS, Eric T; BOURGEA, Joanne et al.Drug metabolism and disposition. 2011, Vol 39, Num 8, pp 1329-1333, issn 0090-9556, 5 p.Article

Comparison of In Vitro Metabolism of Ticlopidine by Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4TALAKAD, Jyothi C; SHAH, Manish B; WALKER, Gregory S et al.Drug metabolism and disposition. 2011, Vol 39, Num 3, pp 539-550, issn 0090-9556, 12 p.Article

Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-GlucuronosyltransferasesCHIMALAKONDA, Krishna C; BRATTON, Stacie M; LE, Vi-Huyen et al.Drug metabolism and disposition. 2011, Vol 39, Num 10, pp 1967-1976, issn 0090-9556, 10 p.Article

Cytochrome P450 2S1 is Reduced by NADPH-Cytochrome P450 ReductaseYI XIAO; SHINKYO, Raku; GUENGERICH, F. Peter et al.Drug metabolism and disposition. 2011, Vol 39, Num 6, pp 944-946, issn 0090-9556, 3 p.Article

Diabetes Mellitus Reduces Activity of Human UDP-Glucuronosyltransferase 2B7 in Liver and Kidney Leading to Decreased Formation of Mycophenolic Acid Acyl-Glucuronide MetaboliteDOSTALEK, Miroslav; COURT, Michael H; HAZARIKA, Suwagmani et al.Drug metabolism and disposition. 2011, Vol 39, Num 3, pp 448-455, issn 0090-9556, 8 p.Article

Discovery of a Novel Allelic Variant of CYP2C8, CYP2C8*11, in Asian Populations and Its Clinical Effect on the Rosiglitazone Disposition In VivoYEO, Chang-Woo; LEE, Su-Jun; SANG SEOP LEE et al.Drug metabolism and disposition. 2011, Vol 39, Num 4, pp 711-716, issn 0090-9556, 6 p.Article

Dose-Dependent Disposition of Methotrexate in Abcc2 and Abcc3 Gene Knockout Murine ModelsZHAN WANG; QINGYU ZHOU; KRUH, Gary D et al.Drug metabolism and disposition. 2011, Vol 39, Num 11, pp 2155-2161, issn 0090-9556, 7 p.Article

Effect of Dimethyl Sulfoxide on In Vitro Cytochrome P4501A2 Mediated Phenacetin O-Deethylation in Human Liver MicrosomesNIROGI, Ramakrishna; KANDIKERE, Vishwottam; BHYRAPUNENI, Gopinadh et al.Drug metabolism and disposition. 2011, Vol 39, Num 11, pp 2162-2164, issn 0090-9556, 3 p.Article

Effects of Acetylenic Epoxygenase Inhibitors on Recombinant Cytochrome P450sVANALSTINE, Melissa A; HOUGH, Lindsay B.Drug metabolism and disposition. 2011, Vol 39, Num 7, pp 1221-1226, issn 0090-9556, 6 p.Article

Efflux Transport Is an Important Determinant of Ethinylestradiol Glucuronide and Ethinylestradiol Sulfate PharmacokineticsZAMEK-GLISZCZYNSKI, Maciej J; DAY, Jeffrey S; HILLGREN, Kathleen M et al.Drug metabolism and disposition. 2011, Vol 39, Num 10, pp 1794-1800, issn 0090-9556, 7 p.Article

Ethanol Induction of CYP2A5: Permissive Role for CYP2E1YONGKE LU; JIAN ZHUGE; DEFENG WU et al.Drug metabolism and disposition. 2011, Vol 39, Num 2, pp 330-336, issn 0090-9556, 7 p.Article

Farnesoid X Receptor Activation by Chenodeoxycholic Acid Induces Detoxifying Enzymes through AMP-Activated Protein Kinase and Extracellular Signal-Regulated Kinase 1/2-Mediated Phosphorylation of CCAAT/Enhancer Binding Protein βNOH, Kyoung; YOUNG MI KIM; YOUNG WOO KIM et al.Drug metabolism and disposition. 2011, Vol 39, Num 8, pp 1451-1459, issn 0090-9556, 9 p.Article

Gestational and Pregnane X Receptor-Mediated Regulation of Placental ATP-Binding Cassette Drug Transporters in MiceGAHIR, Sarabjit S; PIQUETTE-MILLER, Micheline.Drug metabolism and disposition. 2011, Vol 39, Num 3, pp 465-471, issn 0090-9556, 7 p.Article

Hepatocyte Nuclear Factor 4α Regulates Expression of the Mouse Female-Specific Cyp3a41 Gene in the LiverBHADHPRASIT, Wattanaporn; SAKUMA, Tsutomu; KAWASAKI, Yuki et al.Drug metabolism and disposition. 2011, Vol 39, Num 3, pp 490-497, issn 0090-9556, 8 p.Article

Human Pharmacokinetic Prediction of UDP-Glucuronosyltransferase Substrates with an Animal Scale-Up ApproachDEGUCHI, Tsuneo; WATANABE, Nobuaki; IWASAKI, Masaru et al.Drug metabolism and disposition. 2011, Vol 39, Num 5, pp 820-829, issn 0090-9556, 10 p.Article

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