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CRYSTAL STRUCTURES OF ESCHERICHIA COLI AND LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE REFINED AT 1.7 A RESOLUTION. II: ENVIRONMENT OF BOUND NADPH AND IMPLICATIONS FOR CATALYSISFILMAN DJ; BOLIN JT; MATTHEWS DA et al.1982; JOURNAL OF BIOLOGICAL CHEMISTRY; ISSN 0021-9258; USA; DA. 1982; VOL. 257; NO 22; PP. 13663-13672; BIBL. 57 REF.Article

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Expression of dihydrofolate reductase, and of the adjacent EIb region, in an Ad5-dihydrofolate reductase recombinant virusBERKNER, K. L; SHARP, P. A.Nucleic acids research. 1984, Vol 12, Num 4, pp 1925-1941, issn 0305-1048Article

Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase―thymidylate synthase gene of Plasmodium falciparumCOWMAN, A. F; MORRY, M. J; BIGGS, B. A et al.Proceedings of the National Academy of Sciences of the United States of America. 1988, Vol 85, Num 23, pp 9109-9113, issn 0027-8424Article

THE INTERACTION OF AN IONIZING LIGAND WITH ENZYMES HAVING A SINGLE IONIZING GROUP. IMPLICATIONS FOR THE REACTION OF FOLATE ANALOGUES WITH DIHYDROFOLATE REDUCTASESTONE SR; MORRISON JF.1983; BIOCHIMICA ET BIOPHYSICA ACTA; ISSN 0006-3002; NLD; DA. 1983; VOL. 745; NO 3; PP. 237-246; BIBL. 4 REF.Article

Development and evaluation of an enzyme inhibition assay for methotrexateKELLY, M. G.Annals of clinical biochemistry. 1988, Vol 25, Num 5, pp 516-521, issn 0004-5632Article

CRYSTAL STRUCTURE OF AVIAN DIHYDROFOLATE REDUCTASE CONTAINING PHENYLTRIAZINE AND NADPHVOLZ KW; MATHEWS DA; ALDEN RA et al.1982; J. BIOL. CHEM.; ISSN 0021-9258; USA; DA. 1982; VOL. 257; NO 5; PP. 2528-2536; BIBL. 24 REF.Article

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A coupled radiometric assay for dihydrofolate reductase based on the oxidative decarboxylation of D-6-phospho-[1-¹⁴C]gluconateRATHOD, P. K; REYES, P.Analytical biochemistry. 1983, Vol 133, Num 2, pp 425-429, issn 0003-2697Article

Properties of aditoprim, a new antibacterial dihydrofolate reductase inhibitorTHEN, R. L; KELLER, M.Zentralblatt für Veterinärmedizin. Reihe B. Infectious diseases, immunology, food hygiene, veterinary public health. 1988, Vol 35, Num 2, pp 114-120Article

Evidence that a point mutation in dihydrofolate reductase―thymidylate synthase confers resistance to pyrimethamine in falciparum malariaPETERSON, D. S; WALLIKER, D; WELLEMS, T. E et al.Proceedings of the National Academy of Sciences of the United States of America. 1988, Vol 85, Num 23, pp 9114-9118, issn 0027-8424Article

Design of a new substituted 2,4-diamino-5-benzylpyrimidine as inhibitor of bacterial dihydrofolate reductase assisted by molecular graphicsCZAPLINSKY, K.-H; KANSY, M; SEYDEL, J. K et al.Quantitative structure-activity relationships. 1987, Vol 6, Num 2, pp 70-72, issn 0931-8771Article

ANTIFOLATE-RESISTANT CHINESE HAMSTER CELLS. MRNA DIRECTED OVERPRODUCTION OF MULTIPLE DIHYDROFOLATE REDUCTASES FROM A SERIES OF INDEPENDENTLY DERIVED SUBLINES CONTAINING AMPLIFIED DIHYDROFOLATE REDUCTASE GENESMELERA PW; HESSION CA; DAVIDE JP et al.1982; JOURNAL OF BIOLOGICAL CHEMISTRY; ISSN 0021-9258; USA; DA. 1982; VOL. 257; NO 21; PP. 12939-12949; BIBL. 1 P.Article

A flow microcalorimetric method for enzyme activity measurements: application to dihydrofolate reductaseSICA, L; GILLI, R; BRIAND, C et al.Analytical biochemistry. 1987, Vol 165, Num 2, pp 341-348, issn 0003-2697Article

Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analoguesKUYPER, L. F; ROTH, B; GOODFORD, P. J et al.Journal of medicinal chemistry (Print). 1985, Vol 28, Num 3, pp 303-311, issn 0022-2623Article

Detection of active, potentially acetate-oxidizing syntrophs in an anaerobic digester by flux measurement and formyltetrahydrofolate synthetase (FTHFS) expression profilingHORN, Tomoyuki; SASAKI, Daisuke; HARUTA, Shin et al.Microbiology (Reading). 2011, Vol 157, pp 1980-1989, issn 1350-0872, 10 p., 7Article

The ¹H-NMR assignments of the aromatic resonances in complexes of Lactobacillus casei dihydrofolate reductase and the origins of their chemical shiftsBIRDSALL, B; ARNOLD, J. R. P; JIMENEZ-BARBERO, J et al.European journal of biochemistry (Print). 1990, Vol 191, Num 3, pp 659-668, issn 0014-2956, 10 p.Article

A novel form of human polymorphism involving the hDHFR-ψ₁ pseudogene identifies three RFLPsANAGNOU, N. P; ANTONARAKIS, S. E; O'BRIEN, S. J et al.Nucleic acids research. 1987, Vol 15, Num 13, issn 0305-1048, 5501Article

TETRAHYDROFOLATE DEHYDROGENASE CYTOCHEMISTRY AND CLASSIFICATION OF ACUTE LEUKAEMIANANO R; GERVASO MV; INVERNIZZI R et al.1982; ACTA HAEMATOL.; ISSN 0001-5792; CHE; DA. 1982; VOL. 67; NO 3; PP. 160-165; BIBL. 20 REF.Article

Thymidylate synthase-dihydrofolate reductase in protozoaIVANETICH, K. M; SANTI, D. V.Experimental parasitology. 1990, Vol 70, Num 3, pp 367-371, issn 0014-4894Article

The thymidylate synthesis cycle and anticancer drugsDOUGLAS, K. T.Medicinal research reviews (Print). 1987, Vol 7, Num 4, pp 441-475, issn 0198-6325Article

Synthesis of (6S)-5-formyltetrahydropteroyl-polyglutamates and interconversion to other reduced pteroylglutamate derivativesSTOVER, P; SCHIRCH, V.Analytical biochemistry. 1992, Vol 202, Num 1, pp 82-88, issn 0003-2697Article

SELECTIVE AMPLIFICATION OF POLYMORPHIC DIHYDROFOLATE REDUCTASE GENE LOCI IN CHINESE HAMSTER LUNG CELLSLEWIS JA; DAVIDE JP; MELERA PW et al.1982; PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. BIOLOGICAL SCIENCES; ISSN 0273-1134; USA; DA. 1982; VOL. 79; NO 22; PP. 6961-6965; BIBL. 27 REF.Article