Molecular basis of P450 inhibition and activation : Implications for drug development and drug therapy
- Auteur
- SZKLARZ, G. D1 ; HALPERT, J. R2
[1] Department of Basic Pharmaceutical Sciences, West Virginia University, United States
[2] Department of Pharmacology and Toxicology, University of Texas Medical Branch at Galveston, United States - Source
Drug metabolism and disposition. 1998, Vol 26, Num 12, pp 1179-1184 ; ref : 25 ref
- CODEN
- DMDSAI
- ISSN
- 0090-9556
- Domaine scientifique
- Pharmacology drugs
- Editeur
- American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD
- Pays de publication
- United States
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Activation Activité enzymatique Cytochrome P450 Homologie In vitro Inhibition Isozyme Modélisation Mutagenèse dirigée Médicament Métabolisme Relation structure fonction Structure 3 dimensions Cytochrome CYP2B1 Cytochrome CYP3A4
- Mot clé (en)
- Activation Enzymatic activity Cytochrome P450 Homology In vitro Inhibition Isozyme Modeling Site directed mutagenesis Drug Metabolism Structure function relationship Three dimensional structure
- Mot clé (es)
- Activación Actividad enzimática Citocromo P450 Homología In vitro Inhibición Isozima Modelización Mutagénesis dirigida Medicamento Metabolismo Relación estructura función Estructura 3 dimensiones
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002A Sciences biologiques fondamentales et appliquees. Psychologie / 002A02 Biochimie analytique, structurale et metabolique / 002A02E Enzymes et inhibiteurs d'enzymes / 002A02E08 Divers
- Discipline
- Analytical, structural and metabolic biochemistry
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 1639949
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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