Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated keap1
- Auteur
- GUOWEN LIU1 ; EGGLER, Aimee L1 ; DIETZ, Birgit M1 ; MESECAR, Andrew D1 ; BOLTON, Judy L1 ; PEZZUTO, John M2 ; VAN BREEMEN, Richard B1
[1] Department of Medicinal Chemistry and Pharmacognosy, University of Illinois College of Pharmacy, 833 South Wood Street, Chicago, Illinois 60612-7231, United States
[2] Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy, Nursing and Health Sciences, Purdue University, 1330 Heine Pharmacy Building, West Lafayette, Indiana 47907, United States - Source
Analytical chemistry (Washington, DC). 2005, Vol 77, Num 19, pp 6407-6414, 8 p ; ref : 35 ref
- CODEN
- ANCHAM
- ISSN
- 0003-2700
- Domaine scientifique
- Analytical chemistry
- Editeur
- American Chemical Society, Washington, DC
- Pays de publication
- United States
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Alkylation Analyse chimique Antioxydant Chromatographie phase liquide Composé addition Composé naturel Cystéine Désorption laser Enzyme Glutathion Homme Médicament Méthode temps vol Plomb composé Produit naturel Protéine Préparation échantillon Quinone Spectrométrie masse tandem Spectrométrie masse Végétal
- Mot clé (en)
- Alkylation Chemical analysis Antioxidant Liquid chromatography Adduct Natural compound Cysteine Laser desorption Enzyme Glutathione Human Drug Time of flight method Lead compound Natural product Protein Sample preparation Quinone Mass spectrometry MS/MS Mass spectrometry Vegetals
- Mot clé (es)
- Alquilación Análisis químico Antioxidante Cromatografía fase líquida Compuesto adición Compuesto natural Cisteína Desorción láser Enzima Glutatión Hombre Medicamento Método tiempo vuelo Plomo compuesto Producto natural Proteína Preparación muestreo Quinona Espectrometría masa en tándem Espectrometría masa Vegetal
- Classification
- Pascal
- 001 Sciences exactes et technologie / 001C Chimie / 001C04 Chimie analytique / 001C04B Méthodes chromatographiques et méthodes physiques associées à la chromatographie / 001C04B02 Autres méthodes chromatographiques
- Pascal
- 001 Sciences exactes et technologie / 001C Chimie / 001C04 Chimie analytique / 001C04C Méthodes spectrométriques et optiques
- Discipline
- Analytical chemistry
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 17175645
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/ac050892r 
https://dx.doi.org/10.1021/ac050892r
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