Frequency and resistance of CD95 (Fas/Apo-1) gene-transfected tumor cells to CD95-mediated apoptosis by the elimination and methylation of integrated DNA

Auteur

SHIMIZU, Motomu¹ ; YOSHIMOTO, Takayuki² ; SATO, Mayumi¹ ; MATSUZAWA, Akio³ ; TAKEDA, Yasutaka⁴
[1] Medical R&D Center, Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Organization for Medical Research, Tokyo, 113-8613, Japan
[2] Intractable Immune System Disease Research Center, Tokyo Medical University, Tokyo, 160-8402, Japan
[3] Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, 108-8639, Japan
[4] Breast Surgical Oncology Center, Double-Barred Cross Hospital, Japan Anti-tuberculosis Association, Matuyama 3-1-24, Kiyose-shi, Tokyo, 204-8522, Japan

Source

International journal of cancer. = Journal international du cancer. 2006, Vol 119, Num 3, pp 585-592, 8 p ; ref : 38 ref

CODEN

IJCNAW

ISSN

0020-7136

Domaine scientifique

Medical oncology

Editeur

Wiley-Liss, New York, NY

Pays de publication

United States

Type de document

Article

Langue

English

Mot clé auteur

CD95/Fas/Apo-1 apoptosis cDNA deletion cDNA methylation epigenetics mutation frequency

Mot clé (fr)

Animal Antigène Fas Apoptose Cancérologie Carcinome hépatocellulaire DNA complémentaire Délétion Epigénétique Gène Lignée cellulaire établie Mort cellulaire Mutation Méthylation Résistance Souris Transfection Transfert génétique Antigène CD95 Hépatome F6b Appareil digestif pathologie Foie pathologie Génie génétique Génétique Mammalia Rodentia Tumeur maligne Vertebrata

Mot clé (en)

Animal Fas Antigen Apoptosis Cancerology Hepatocellular carcinoma Complementary DNA Deletion Epigenetics Gene Established cell line Cell death Mutation Methylation Resistance Mouse Transfection Genetic transfer Digestive diseases Hepatic disease Genetic engineering Genetics Mammalia Rodentia Malignant tumor Vertebrata

Mot clé (es)

Animal Antígeno Fas Apoptosis Cancerología Carcinoma hepatocelular DNA complementario Deleción Epigenética Gen Línea celular establecida Muerte celular Mutación Metilación Resistencia Ratón Transfección Transferencia genética Aparato digestivo patología Hígado patología Ingeniería genética Genética Mammalia Rodentia Tumor maligno Vertebrata

Classification

Pascal

002 Sciences biologiques et medicales / 002B Sciences medicales / 002B04 Tumeurs / 002B04D Tumeurs animales. Tumeurs expérimentales / 002B04D07 Tumeurs expérimentales de l'appareil digestif et de l'abdomen

Discipline

Tumours

Provenance

Inist-CNRS

Base de données

PASCAL

Identifiant INIST

17899743

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