PKU is a reversible neurodegenerative process within the nigrostriatum that begins as early as 4 weeks of age in Pahenu2 mice
- Auteur
- EMBURY, Jennifer E1 ; CHARRON, Catherine E2 ; MARTYNYUK, Anatoly3 ; ZORI, Andreas G1 ; BIN LIU4 ; ALI, Syed F5 ; ROWLAND, Neil E6 ; LAIPIS, Philip J1
[1] Department of Biochemistry and Molecular Biology, PO Box 100245, College of Medicine, University of Florida, Gainesville, FL 32610, United States
[2] National Heart and Lung Institute, Imperial College School of Medicine, London, United Kingdom
[3] Department of Anesthesiology, College of Medicine, University of Florida, Gainesville, FL 32610, United States
[4] Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL 32610, United States
[5] Neurochemistry Laboratory, National Center for Toxicology Research/FDA, Jefferson, AR 72079, United States
[6] Department of Psychology, College of Liberal of Arts and Sciences, University of Florida, Gainesville, FL 32610, United States - Source
Brain research. 2007, Vol 1127, pp 136-150, 15 p ; ref : 1 p.1/4
- CODEN
- BRREAP
- ISSN
- 0006-8993
- Domaine scientifique
- Neurology; Physiology, morphology
- Editeur
- Elsevier, Amsterdam
/
Elsevier, London
/
Elsevier, New York, NY
- Pays de publication
- Netherlands
- Type de document
- Article
- Langue
- English
- Mot clé auteur
- Adeno-associated virus Gene therapy Monoamines Oxidative stress Phenylketonuria
- Mot clé (fr)
- Age Animal Corps strié Dégénérescence Locus niger Monoamine Phénylcétonurie Précoce Souris Stress oxydatif Thérapie génique Aminoacidopathie Encéphale Enzymopathie Maladie héréditaire Mammalia Métabolisme pathologie Noyau gris central Rodentia Système nerveux central Système nerveux pathologie Vertebrata
- Mot clé (en)
- Age Animal Corpus striatum Degeneration Locus niger Monoamine Phenylketonuria Early Mouse Oxidative stress Gene therapy Aminoacid disorder Encephalon Enzymopathy Genetic disease Mammalia Metabolic diseases Basal ganglion Rodentia Central nervous system Nervous system diseases Vertebrata
- Mot clé (es)
- Edad Animal Cuerpo estriado Degeneración Locus níger Monoamina Fenilcetonuria Precoz Ratón Estrés oxidativo Terapia génica Aminoacido alteración Encéfalo Enzimopatía Enfermedad hereditaria Mammalia Metabolismo patología Núcleo basal Rodentia Sistema nervioso central Sistema nervioso patología Vertebrata
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B22 Maladies metaboliques / 002B22D Maladies métaboliques héréditaires et congénitales / 002B22D01 Aminoacidopathies
- Discipline
- Metabolic diseases
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 18440178
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.brainres.2006.09.101 
https://dx.doi.org/10.1016/j.brainres.2006.09.101
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