Apoptotic cell death : A possible key event in mediating the in vitro anti-proliferative effect of a novel copper(II) complex, [Cu(4-Mecdoa) (phen)2] (phen=phenanthroline, 4 -mecdoa=4 -methylcoumarin -6, 7-dioxactetate), in human malignant cancer cells
- Auteur
- THATI, Bhumika1 2 ; NOBLE, Andy1 2 ; CREAVEN, Bernadette S1 2 ; WALSH, Maureen1 2 ; KAVANAGH, Kevin1 3 ; EGAN, Denise A1 2
[1] Centre for Pharmaceutical Research and Development, Institute of Technology, Tallaght, Dublin, Ireland
[2] Department of Science, Institute of Technology, Tallaght, Dublin, Ireland
[3] Biology Department, National University of Ireland, Maynooth, Co. Kildare, Ireland - Source
European journal of pharmacology. 2007, Vol 569, Num 1-2, pp 16-28, 13 p ; ref : 1 p.1/2
- CODEN
- EJPHAZ
- ISSN
- 0014-2999
- Domaine scientifique
- Pharmacology drugs
- Editeur
- Elsevier, Amsterdam
- Pays de publication
- Netherlands
- Type de document
- Article
- Langue
- English
- Mot clé auteur
- Apoptosis Caspase activity Cell cycle progression Copper- coumarin-phenanthroline complex PARP cleavage
- Mot clé (fr)
- Apoptose Caspase Cellule tumorale Coumarine dérivé Cuivre II Complexe Cuivre complexe Cycle cellulaire Cysteine endopeptidases Homme In vitro Mort cellulaire Tumeur maligne Phénanthroline dérivé Enzyme Hydrolases Peptidases
- Mot clé (en)
- Apoptosis Caspase Tumor cell Coumarine derivatives Copper II Complexes Copper complex Cell cycle Cysteine endopeptidases Human In vitro Cell death Malignant tumor Enzyme Hydrolases Peptidases
- Mot clé (es)
- Apoptosis Caspase Célula tumoral Cobre II Complejo Cobre complejo Ciclo celular Cysteine endopeptidases Hombre In vitro Muerte celular Tumor maligno Enzima Hydrolases Peptidases
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B02 Pharmacologie. Traitements medicamenteux
- Discipline
- General pharmacology
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 18967864
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejphar.2007.04.064 
https://dx.doi.org/10.1016/j.ejphar.2007.04.064
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