A multisubstrate adduct inhibitor of AICAR transformylase
- Auteur
- WALL, M1 ; JAE HOON SHIM1 ; BENKOVIC, S. J1
[1] Department of Chemistry, 414 Wartik Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802, United States - Source
Journal of medicinal chemistry (Print). 1999, Vol 42, Num 18, pp 3421-3424 ; ref : 24 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Domaine scientifique
- Pharmacology drugs
- Editeur
- American Chemical Society, Washington, DC
- Pays de publication
- United States
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Activité biologique Anticancéreux Carboxamide Carboxylate Complexe enzyme inhibiteur Composé bicyclique Diacide carboxylique Fluorescence Hétérocycle azote Imidazole dérivé In vitro Inhibiteur enzyme Nucléotide Phosphate organique Phosphoribosylaminoimidazolecarboxamide formyltransferase Synthèse chimique α-Aminoacide 8-Désazafolique acide10-[3-(4-carbamoyl-1-(5-O-phosphono-β-D-ribofuranosyl)imidazol-4-yl)acryloyl] Imidazole-4-carboxylique acide dérivé Pyrido[3,2-d]pyrimidine dérivé Pyridopyrimidine β-DADF Enzyme Transferases
- Mot clé (en)
- Biological activity Antineoplastic agent Carboxamide Carboxylate Inhibitor enzyme complex Bicyclic compound Dicarboxylic acid Fluorescence Nitrogen heterocycle Imidazole derivatives In vitro Enzyme inhibitor Nucleotide Organic phosphate Phosphoribosylaminoimidazolecarboxamide formyltransferase Chemical synthesis α-Aminoacid Enzyme Transferases
- Mot clé (es)
- Actividad biológica Anticanceroso Carboxamida Carboxilato Complejo enzima inhibidor Compuesto bicíclico Diácido carboxílico Fluorescencia Heterociclo nitrógeno Imidazol derivado In vitro Inhibidor enzima Nucleótido Fosfato orgánico Phosphoribosylaminoimidazolecarboxamide formyltransferase Síntesis química α-Aminoácido Enzima Transferases
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B02 Pharmacologie. Traitements medicamenteux / 002B02R Anticancéreux / 002B02R01 Généralités
- Discipline
- Pharmacological treatments
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 1970279
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm990323+ 
https://dx.doi.org/10.1021/jm990323+
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