In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists : Trends across multiple chemical series
- Auteur
- NERSESIAN, Diana L1 ; BLACK, Lawrence A1 ; MILLER, Thomas R1 ; VORTHERMS, Timothy A1 ; ESBENSHADE, Timothy A1 ; HANCOCK, Arthur A1 ; COWART, Marlon D1
[1] Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, IL 60064, United States - Source
Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 1, pp 355-359, 5 p ; ref : 9 ref
- ISSN
- 0960-894X
- Domaine scientifique
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Editeur
- Elsevier, Oxford
- Pays de publication
- United Kingdom
- Type de document
- Article
- Langue
- English
- Mot clé auteur
- ADHD Histamine H3 Imidazoles Serotonin
- Mot clé (fr)
- Animal Antagoniste Dérivé de la pyrrolidine Histamine Homme Hyperactivité In vitro Neurotransmetteur Rat Relation structure activité Récepteur histaminergique H3 Synthèse chimique Sélectivité Sérotonine Trouble de l'attention Trouble déficitaire de l'attention avec hyperactivité Composé bas poids moléculaire Pyrrolidine(1-[2-aryléthyl]-2-méthyl) Pyrrolidine(1-[hétéryléthyl]-2-méthyl) Mammalia Rodentia Vertebrata
- Mot clé (en)
- Animal Antagonist Pyrrolidine derivatives Histamine Human Hyperactivity In vitro Neurotransmitter Rat Structure activity relation H3 histamine receptor Chemical synthesis Selectivity Serotonin Attentional disorder Attention disorder with hyperactivity Low molecular weight compound Mammalia Rodentia Vertebrata
- Mot clé (es)
- Animal Antagonista Histamina Hombre Hiperactividad In vitro Neurotransmisor Rata Relación estructura actividad Receptor histaminérgico H3 Síntesis química Selectividad Serotonina Trastorno atención Trastorno por déficit de atención e hiperactividad Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B02 Pharmacologie. Traitements medicamenteux / 002B02B Neuropharmacologie / 002B02B02 Psychoanaleptiques: stimulant snc, antidépresseur, nootrope, normothymique..., (maladie d'alzheimer)
- Francis
- 770 Psychologie. Psychanalyse. Psychiatrie / 770-E Psychopharmacologie / 770-E02 Psychoanaleptiques: stimulant SNC antidépresseur, nootrope, normothymique…
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Provenance
- Inist-CNRS
- Base de données
- FRANCIS ; PASCAL
- Identifiant INIST
- 20037447
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmcl.2007.10.067 
https://dx.doi.org/10.1016/j.bmcl.2007.10.067
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