Crypt stem cells as the cells-of-origin of intestinal cancer
- Auteur
- BARKER, Nick1 2 ; RIDGWAY, Rachel A3 ; VAN ES, Johan H1 2 ; VAN DE WETERING, Marc1 2 ; BEGTHEL, Harry1 2 ; VAN DEN BORN, Maaike1 2 ; DANENBERG, Esther1 2 ; CLARKE, Alan R4 ; SANSOM, Owen J3 ; CLEVERS, Hans1 2
[1] Hubrecht Institute for Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584CT Utrecht, Netherlands
[2] University Medical Centre Utrecht, Netherlands
[3] Beatson Institute for Cancer Research, Glasgow G611BD, United Kingdom
[4] cardiff School of Biosciences, Cardiff CF10 3US, United Kingdom - Source
Nature (London). 2009, Vol 457, Num 7229, pp 608-611, 4 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Domaine scientifique
- Multidisciplinary
- Editeur
- Nature Publishing Group, London
- Pays de publication
- United Kingdom
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Animal Cancer de l'intestin Cancérologie Carcinogenèse Cellule souche Glande Lieberkuhn Gène suppresseur tumeur Origine cellule Souris Transformation maligne Gène APC Cancer Génétique Mammalia Pathologie de l'appareil digestif Pathologie de l'intestin Rodentia Tumeur maligne Vertebrata
- Mot clé (en)
- Animal Intestinal cancer Cancerology Carcinogenesis Stem cell Lieberkuhn gland Tumor suppressor gene Cell origin Mouse Malignant transformation APC Gene Cancer Genetics Mammalia Digestive diseases Intestinal disease Rodentia Malignant tumor Vertebrata
- Mot clé (es)
- Animal Cáncer del intestino Cancerología Carcinogénesis Célula primitiva Glándula Lieberkuhn Gen supresor tumor Origen celular Ratón Transformación maligna Gen APC Cáncer Genética Mammalia Aparato digestivo patología Intestino patología Rodentia Tumor maligno Vertebrata
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B04 Tumeurs / 002B04D Tumeurs animales. Tumeurs expérimentales / 002B04D07 Tumeurs expérimentales de l'appareil digestif et de l'abdomen
- Discipline
- Tumours
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 21030270
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature07602 
https://dx.doi.org/10.1038/nature07602
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