Azole antimicrobial pharmacophore-based tetrazoles : Synthesis and biological evaluation as potential antimicrobial and anticonvulsant agents
- Auteur
- ROSTOM, Sherif A. F1 ; ASHOUR, Hayam M. A2 ; ABD EL RAZIK, Heba A2 ; ABD EL FATTAH, Abd El Fattah H3 ; EL-DIN, Nagwa N4
[1] Department of Chemistry, Faculty of Science, King Abdulaziz University, PO Box 80203, Jeddah 21589, Saudi Arabia
[2] Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt
[3] Department of Microbiology, High Institute of Public Health, Alexandria University, Alexandria, Egypt
[4] Department of Pharmacology, Faculty of Medicine, Alexandria University, Alexandria 21521, Egypt - Source
Bioorganic & medicinal chemistry. 2009, Vol 17, Num 6, pp 2410-2422, 13 p
- ISSN
- 0968-0896
- Domaine scientifique
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Editeur
- Elsevier, Amsterdam
- Pays de publication
- Netherlands
- Type de document
- Article
- Langue
- English
- Mot clé auteur
- 1,3,4-Oxadiazoles 1,3,4-Triazoles 1H-Tetrazoles Antibacterial activity Anticonvulsant activity Antifungal activity Azoles Pyrazoles
- Mot clé (fr)
- Alcool Animal Antibactérien Anticonvulsivant Antifongique Antimicrobien Aspergillus fumigatus Bacillus subtilis Candida albicans Chlore Composé organique Dérivé d'azole Dérivé du pyrazole Dérivé du triazole Dérivé du tétrazole In vitro Modélisation Relation structure activité Souris Staphylococcus aureus Synthèse chimique 1,3,4-Oxadiazole dérivé 1,3,4-Oxadiazole-2-thiol(5-[1-(4-chlorophényl)-2-(5-phényltétrazol-2-yl)éthoxyméthyl]) Ethanol(2-[5-benzyltétrazol-2-yl]-1-[4-chlorophényl]) Thiosemicarbazides Bacillaceae Bacillales Bactérie Fungi Imperfecti Fungi Mammalia Micrococcaceae Micrococcales Rodentia Vertebrata
- Mot clé (en)
- Alcohol Animal Antibacterial agent Anticonvulsant Antifungal agent Antimicrobial agent Aspergillus fumigatus Bacillus subtilis Candida albicans Chlorine Organic compounds Azole derivatives Pyrazole derivatives Triazole derivatives Tetrazole derivatives In vitro Modeling Structure activity relation Mouse Staphylococcus aureus Chemical synthesis Thiosemicarbazides Bacillaceae Bacillales Bacteria Fungi Imperfecti Fungi Mammalia Micrococcaceae Micrococcales Rodentia Vertebrata
- Mot clé (es)
- Alcohol Animal Antibacteriano Anticonvulsivante Antifúngico Antimicrobiano Aspergillus fumigatus Bacillus subtilis Candida albicans Cloro Compuesto orgánico Azol derivado Pirazol derivado Triazol derivado Tetrazol derivado In vitro Modelización Relación estructura actividad Ratón Staphylococcus aureus Síntesis química Bacillaceae Bacillales Bacteria Fungi Imperfecti Fungi Mammalia Micrococcaceae Micrococcales Rodentia Vertebrata
- Classification
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B02 Pharmacologie. Traitements medicamenteux / 002B02B Neuropharmacologie / 002B02B06 Anticonvulsivants. Antiépileptiques. Antiparkinsoniens
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B02 Pharmacologie. Traitements medicamenteux / 002B02S Antibiotiques. Antiinfectieux. Antiparasitaires / 002B02S01 Généralités
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B02 Pharmacologie. Traitements medicamenteux / 002B02S Antibiotiques. Antiinfectieux. Antiparasitaires / 002B02S02 Antibactériens
- Pascal
- 002 Sciences biologiques et medicales / 002B Sciences medicales / 002B02 Pharmacologie. Traitements medicamenteux / 002B02S Antibiotiques. Antiinfectieux. Antiparasitaires / 002B02S04 Antifongiques
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 21338170
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2009.02.004 
https://dx.doi.org/10.1016/j.bmc.2009.02.004
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